Výsledky vyhledávání - "Alejandro Nadra"

Optimization and validation of a Protein Phosphatase inhibition assay for accessible microcystin detection

Autor: Ezequiel Jorge Alba Posse, Carolina González, Pedro Carriquiriborde, Alejandro Nadra, Javier Gasulla

The presence of cyanobacterial toxins in freshwater constitutes an increasing public health concern, especially affecting developing countries where the high cost of available methods makes monitoring programs difficult. The phosphatase inhibition as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc61f293a9a166df5f6dfd1d17971bf8
https://doi.org/10.1101/2022.08.16.502937

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Transcription factor specificity limits the number of DNA-binding motifs

Autor: Ariel Alejandro Aptekmann, Ignacio Enrique Sanchez, Denys Bulavka, Alejandro Nadra

Publikováno v: PLoS ONE, Vol 17, Iss 1, p e0263307 (2022)
PLoS ONE

We study the limits imposed by transcription factor specificity on the maximum number of binding motifs that can coexist in a gene regulatory network, using the SwissRegulon Fantom5 collection of 684 human transcription factor binding sites as a mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9cc36fd94e496b0bf7115e1ad6e6d4
https://doi.org/10.1371/journal.pone.0263307

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Solution structure of the HPV-16 E2 DNA binding domain, a transcriptional regulator with a dimeric beta-barrel fold

Autor: Alejandro Nadra, Eliseo, T., Mok, Y. K., Almeida, C. L., Bycroft, M., Paci, M., Prat-Gay, G., Cicero, D. O.

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::785c9e7de66ece96dbf21d7a482ef539
http://hdl.handle.net/2108/13117

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Distinctive Cognate Sequence Discrimination, Bound DNA Conformation, and Binding Modes in the E2 C-Terminal Domains from Prototype Human and Bovine Papillomaviruses

Autor: Alejandro Nadra, Gonzalo Prat Gay, Fernando Goldbaum, Diego Ferreiro, Luis Mauricio TR Lima, Leonardo Gabriel Alonso

The C-terminal DNA binding domain of the E2 protein is involved in transcriptional regulation and DNA replication in papillomaviruses. At low ionic strength, the domain has a tendency to form aggregates, a process readily reversible by the addition o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d47dad0f5ac5e01b36b68ab66128b86
https://pubs.acs.org/doi/abs/10.1021/bi001694r

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