Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Alejandro M. Cuadros"'
2
High affinity protein surface binding through co-engineering of nanoparticles and proteins
Autor: Moumita Ray, Giorgia Brancolini, David C. Luther, Ziwen Jiang, Roberto Cao-Milán, Alejandro M. Cuadros, Andrew Burden, Vincent Clark, Subinoy Rana, Rubul Mout, Ryan F. Landis, Stefano Corni, Vincent M. Rotello
Publikováno v: Nanoscale
Nanoscale, vol 14, iss 6
Nanoscale (Online) 14 (2022): 2411–2418. doi:10.1039/d1nr07497k
info:cnr-pdr/source/autori:Ray M.; Brancolini G.; Luther D.C.; Jiang Z.; Cao-Milan R.; Cuadros A.M.; Burden A.; Clark V.; Rana S.; Mout R.; Landis R.F.; Corni S.; Rotello V.M./titolo:High affinity protein surface binding through co-engineering of nanoparticles and proteins/doi:10.1039%2Fd1nr07497k/rivista:Nanoscale (Online)/anno:2022/pagina_da:2411/pagina_a:2418/intervallo_pagine:2411–2418/volume:14
Control over supramolecular recognition between proteins and nanoparticles (NPs) is of fundamental importance in therapeutic applications and sensor development. Most NP-protein binding approaches use 'tags' such as biotin or His-tags to provide high
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be80cf2b66ffd6f8f5122fbda8bd1df
https://doi.org/10.1039/d1nr07497k
Zobrazit plný text záznamu
4
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis
Autor: Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, Anke Vandekeere, Alejandro M. Cuadros, Juan Fernández-García, Carla Riera-Domingo, Cristina Jauset, Mélanie Planque, H. Furkan Alkan, David Nittner, Dongmei Zuo, Lindsay A. Broadfield, Sweta Parik, Antonino Alejandro Pane, Francesca Rizzollo, Gianmarco Rinaldi, Tao Zhang, Shao Thing Teoh, Arin B. Aurora, Panagiotis Karras, Ines Vermeire, Dorien Broekaert, Joke Van Elsen, Maximilian M. L. Knott, Martin F. Orth, Sofie Demeyer, Guy Eelen, Lacey E. Dobrolecki, Ayse Bassez, Thomas Van Brussel, Karl Sotlar, Michael T. Lewis, Harald Bartsch, Manfred Wuhrer, Peter van Veelen, Peter Carmeliet, Jan Cools, Sean J. Morrison, Jean-Christophe Marine, Diether Lambrechts, Massimiliano Mazzone, Gregory J. Hannon, Sophia Y. Lunt, Thomas G. P. Grünewald, Morag Park, Jacco van Rheenen, Sarah-Maria Fendt
Publikováno v: Nature
Rossi, M, Altea-Manzano, P, Demicco, M, Doglioni, G, Bornes, L, Fukano, M, Vandekeere, A, Cuadros, A M, Fernández-García, J, Riera-Domingo, C, Jauset, C, Planque, M, Alkan, H F, Nittner, D, Zuo, D, Broadfield, L A, Parik, S, Pane, A A, Rizzollo, F, Rinaldi, G, Zhang, T, Teoh, S T, Aurora, A B, Karras, P, Vermeire, I, Broekaert, D, Elsen, J V, Knott, M M L, Orth, M F, Demeyer, S, Eelen, G, Dobrolecki, L E, Bassez, A, Brussel, T V, Sotlar, K, Lewis, M T, Bartsch, H, Wuhrer, M, Veelen, P V, Carmeliet, P, Cools, J, Morrison, S J, Marine, J C, Lambrechts, D, Mazzone, M, Hannon, G J, Lunt, S Y, Grünewald, T G P, Park, M, Rheenen, J V & Fendt, S M 2022, ' PHGDH heterogeneity potentiates cancer cell dissemination and metastasis ', Nature, vol. 605, no. 7911, pp. 747-753 . https://doi.org/10.1038/s41586-022-04758-2
Nature, 605(7911), 747-+. NATURE PORTFOLIO
Cancer metastasis requires the transient activation of cellular programs enabling dissemination and seeding in distant organs1. Genetic, transcriptional and translational heterogeneity contributes to this dynamic process2,3. Metabolic heterogeneity h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e5caca229c7c7298416a476ab4cc79
https://hdl.handle.net/1887/3480405
Zobrazit plný text záznamu
6
Nutrient metabolism and cancer in thein vivocontext: a metabolic game of give and take
Autor: Lindsay A. Broadfield, Sarah-Maria Fendt, Alejandro M Cuadros, Patricia Altea-Manzano
Publikováno v: EMBO Rep
EMBO reports
Nutrients are indispensable resources that provide the macromolecular building blocks and energy requirements for sustaining cell growth and survival. Cancer cells require several key nutrients to fulfill their changing metabolic needs as they progre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e99a4a27b0c231def93e76af9c6541b
https://lirias.kuleuven.be/handle/123456789/663038
Zobrazit plný text záznamu
7
A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-Organelle Buffering
Autor: Tsz-Leung To, Alejandro M. Cuadros, John G. Doench, David E. Root, Vamsi K. Mootha, Scott B. Vafai, Yang Li, Wendy H. W. Hung, Hardik Shah, Sharon H. Kim, Stuart L. Schreiber, Amy Goodale, Ryan H. Boe, Federica Piccioni, Daniel H. F. Rubin, Zohra Kalani, Sneha Rath, John K. Eaton
Publikováno v: Cell
Summary Mitochondrial dysfunction is associated with a spectrum of human conditions, ranging from rare, inborn errors of metabolism to the aging process. To identify pathways that modify mitochondrial dysfunction, we performed genome-wide CRISPR scre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc12a7ef6c2bc87eefb3a89c129a6b0b
https://europepmc.org/articles/PMC7053407/
Zobrazit plný text záznamu
8
In vivo CRISPR screen defines Slc25a37 as an organ-specific regulator of antioxidant metabolism in metastasis
Autor: Alejandro M. Cuadros, Juan Fernández-Garcia, Mélanie Planque, Patricia Altea-Manzano, Tessa Schalley, Ines Vermeire, Dorien Broekaert, Qi Wu, Thomas Van Brussel, Sophia Leduc, Marion Maetens, Ha-Linh Nguyen, Karen Van Baelen, Naama Darzi, Giuseppe Floris, Hans Wildiers, Christine Desmedt, Diether Lambrechts, Sarah-Maria Fendt
Publikováno v: bioRxiv
BioRxiv
SUMMARYMetastasizing cancer cells must adapt their metabolism to the nutrient environment of distant organs. We performed a loss-of-function CRISPR screen against Solute Carrier Transporters (SLCs) in a breast cancer mouse model to define nutrient re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd50375e81c677cfd101a87b9aac54f
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje