Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alejandro Jimenez-Sanchez"'
Autor:
Nikhil Bharti, Leonardo Santos, Marcos Davyt, Stine Behrmann, Marie Eichholtz, Alejandro Jimenez-Sanchez, Jeong S. Hong, Andras Rab, Eric J. Sorscher, Suki Albers, Zoya Ignatova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Nonsense mutations – the underlying cause of approximately 11% of all genetic diseases – prematurely terminate protein synthesis by mutating a sense codon to a premature stop or termination codon (PTC). An emerging therapeutic strategy t
Externí odkaz:
https://doaj.org/article/7320e409d0a640aa9c9dacd192b22128
Autor:
Roy Rabbie, Naser Ansari-Pour, Oliver Cast, Doreen Lau, Francis Scott, Sarah J. Welsh, Christine Parkinson, Leila Khoja, Luiza Moore, Mark Tullett, Kim Wong, Ingrid Ferreira, Julia M. Martínez Gómez, Mitchell Levesque, Ferdia A. Gallagher, Alejandro Jiménez-Sánchez, Laura Riva, Martin L. Miller, Kieren Allinson, Peter J. Campbell, Pippa Corrie, David C. Wedge, David J. Adams
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Metastatic melanoma is associated with a poor prognosis and understanding the genetic features of metastases may enable better treatment strategies. Here, the authors analyse multiple metastases from individual patients finding high levels of heterog
Externí odkaz:
https://doaj.org/article/88af25cb99664cab9677a9f33b3cdf38
Autor:
Alejandro Jiménez-Sánchez
Publikováno v:
Evolutionary Bioinformatics, Vol 2016, Iss 12, Pp 121-131 (2016)
Externí odkaz:
https://doaj.org/article/bd55ca4af06d4a18967d26c21ac53e84
Autor:
Alejandro Jiménez-Sánchez
Publikováno v:
Evolutionary Bioinformatics, Vol 12 (2016)
RAC proteins are small GTPases involved in important cellular processes in eukaryotes, and their deregulation may contribute to cancer. Activation of RAC proteins is regulated by DOCK and DBL protein families of guanine nucleotide exchange factors (G
Externí odkaz:
https://doaj.org/article/67ff65cb19aa40428a09e89ee2958f69