Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alejandro Gran-Scheuch"'
Autor:
Alejandro Gran-Scheuch, Javiera Ramos-Zuñiga, Edwar Fuentes, Denisse Bravo, José M. Pérez-Donoso
Publikováno v:
Microorganisms, Vol 8, Iss 11, p 1749 (2020)
Diesel oil is the main source of energy used in Antarctica. Since diesel is composed of toxic compounds such as polycyclic aromatic hydrocarbons (PAHs) and heavy metals, it represents a constant threat to the organisms inhabiting this continent. In t
Externí odkaz:
https://doaj.org/article/252b1a6b47fc49c6b1742cd0e124aa58
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Actinobacteria are an important source of commercial (bio)compounds for the biotechnological and pharmaceutical industry. They have also been successfully exploited in the search of novel biocatalysts. We set out to explore a recently identified acti
Externí odkaz:
https://doaj.org/article/7bf12a0d3e854e7cbc305edb7b8e163e
Autor:
Alejandro Gran-Scheuch, Edwar Fuentes, Denisse M. Bravo, Juan Cristobal Jiménez, José M. Pérez-Donoso
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Antarctica is an attractive target for human exploration and scientific investigation, however the negative effects of human activity on this continent are long lasting and can have serious consequences on the native ecosystem. Various areas of Antar
Externí odkaz:
https://doaj.org/article/a20eb1eddddb4c2d953a11b7858f2382
Publikováno v:
Lugtenburg, T, Gran-Scheuch, A & Drienovská, I 2023, ' Non-canonical amino acids as a tool for the thermal stabilization of enzymes ', Protein Engineering, Design and Selection, vol. 36, gzad003, pp. 1-10 . https://doi.org/10.1093/protein/gzad003
Biocatalysis has become a powerful alternative for green chemistry. Expanding the range of amino acids used in protein biosynthesis can improve industrially appealing properties such as enantioselectivity, activity and stability. This review will spe
Publikováno v:
ACS Sustainable Chemistry and Engineering. AMER CHEMICAL SOC
Flavin as a cofactor is an extremely versatile molecule that participates in a wide range of biochemical reactions. A special characteristic of the flavin cofactor, unique for a metal free cofactor, is its ability to react in its reduced form with mo
Autor:
Alejandro Gran-Scheuch, Mohammad Saifuddin, Milos Trajkovic, Alvigini Laura, Marco W. Fraaije, Andrea Mattevi, Yiming Guo
Publikováno v:
ChemBioChem. WILEY-V C H VERLAG GMBH
ChemBioChem 2021, 22
'ChemBioChem ', vol: 22, pages: 3225-3233 (2021)
ChemBioChem 2021, 22
'ChemBioChem ', vol: 22, pages: 3225-3233 (2021)
The vanillyl-alcohol oxidase (VAO) family is a rich source of biocatalysts for the oxidative bioconversion of phenolic compounds. Through genome mining and sequence comparisons, we found that several family members lack a generally conserved catalyti
Publikováno v:
ACS Catalysis. 9:11207-11241
Pollution, accidents, and misinformation have earned the pharmaceutical and chemical industry a poor public reputation, despite their undisputable importance to society. Biotechnological advances hold the promise to enable a future of drastically red
Publikováno v:
Methods in enzymology. 647
The use of enzymes in organic synthesis is highly appealing due their remarkably high chemo-, regio- and enantioselectivity. Nevertheless, for biosynthetic routes to be industrially useful, the enzymes must fulfill several requirements. Particularly,
Autor:
Alejandro Gran Scheuch
Biocatalysis is maturing to be a serious alternative to classical chemical transformations and this hopefully can contribute to a greener industry and new products at the same time. This thesis aimed to be a contribution to the field of biocatalysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fa42a1b645735b0ffa813cd08f9594
https://doi.org/10.33612/diss.154338097
https://doi.org/10.33612/diss.154338097
Autor:
Marco W. Fraaije, Jörn Piel, Roy A. Meoded, Agneya Bhushan, Reiko Ueoka, Alejandro Gran-Scheuch
Publikováno v:
Angewandte Chemie (International Ed. in English)
Bacterial trans‐acyltransferase polyketide synthases (trans‐AT PKSs) are multimodular megaenzymes that biosynthesize many bioactive natural products. They contain a remarkable range of domains and module types that introduce different substituent