Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alejandro García-Núñez"'
Autor:
Gema Jiménez-Gómez, Antonio Campos-Caro, Alejandro García-Núñez, Alberto Gallardo-García, Antonio Molina-Hidalgo, Antonio León-Jiménez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5722 (2024)
Silicosis caused by engineered stone (ES-silicosis) is an emerging worldwide issue characterized by inflammation and fibrosis in the lungs. To our knowledge, only a few reports have investigated leukocyte/lymphocyte subsets in ES-silicosis patients.
Externí odkaz:
https://doaj.org/article/f790a76a45ab41c1a058139854278272
Autor:
Elena Fernández-Suárez, María González-del Pozo, Alejandro García-Núñez, Cristina Méndez-Vidal, Marta Martín-Sánchez, José Manuel Mejías-Carrasco, Manuel Ramos-Jiménez, María José Morillo-Sánchez, Enrique Rodríguez-de la Rúa, Salud Borrego, Guillermo Antiñolo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Inherited retinal dystrophies (IRDs) are a clinically and genetically heterogeneous group of disorders that often severely impair vision. Some patients manifest poor central vision as the first symptom due to cone-dysfunction, which is consistent wit
Externí odkaz:
https://doaj.org/article/57db66d951b541db8ca7fb0b46677dc5
Autor:
Alejandro García-Núñez, Gema Jiménez-Gómez, Antonio Hidalgo-Molina, Juan Antonio Córdoba-Doña, Antonio León-Jiménez, Antonio Campos-Caro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Patients with silicosis caused by occupational exposure to engineered stone (ES) present a rapid progression from simple silicosis (SS) to progressive massive fibrosis (PMF). Patient classification follows international rules based on radiol
Externí odkaz:
https://doaj.org/article/3d5d364b080f41b3b4e4f257e15ea4da
Autor:
Antonio Campos-Caro, Gema Jiménez-Gómez, Alejandro García-Núñez, Antonio Hidalgo-Molina, Antonio León-Jiménez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1541 (2023)
Engineered stone silicosis has become an occupational epidemic disease that progresses rapidly to progressive massive fibrosis with respiratory failure and death, and there is no effective treatment. Silica deposition in the lung triggers a series of
Externí odkaz:
https://doaj.org/article/357c5f4c570f4ca191108cf77372633c
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72213 (2013)
Mutations in the human homolog of the Vhlh gene [encoding the von-Hippel Lindau (VHL) protein] lead to tumor development. In mice, depletion of Vhlh in pancreatic ß-cells causes perturbed glucose homeostasis, but the role of this gene in other pancr
Externí odkaz:
https://doaj.org/article/b62c61acb0974eae90682931b8412174
Publikováno v:
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Hypoxia inducible factors (HIFs) are critical regulators of the response to oxygen deficiency by activating target genes involved in a variety of biological functions. HIFs have been implicated in the pathophysiology of numerous pathologies including
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e72213 (2013)
Hebrok, Matthias; Puri, S; García-Núñez, A; & Cano, DA. (2013). Elimination of Von Hippel-Lindau Function Perturbs Pancreas Endocrine Homeostasis in Mice. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/23f576rv
PLoS ONE, Vol 8, Iss 8, p e72213 (2013)
Hebrok, Matthias; Puri, S; García-Núñez, A; & Cano, DA. (2013). Elimination of Von Hippel-Lindau Function Perturbs Pancreas Endocrine Homeostasis in Mice. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/23f576rv
Mutations in the human homolog of the Vhlh gene [encoding the von-Hippel Lindau (VHL) protein] lead to tumor development. In mice, depletion of Vhlh in pancreatic s-cells causes perturbed glucose homeostasis, but the role of this gene in other pancre