Immunophenotyping to improve the mechanistic understanding of idiosyncratic drug-induced liver injury: clinical implications and future directions

Autor: Alejandro Cueto-Sánchez, Daniel E. Di Zeo-Sánchez, Antonio Segovia-Zafra, Gonzalo Matilla-Cabello, Ana Bodoque-García, María Isabel Lucena, Marina Villanueva-Paz

Publikováno v: Exploration of Digestive Diseases, Vol 2, Iss 2, Pp 56-76 (2023)

The late event onset of a fraction of idiosyncratic drug-induced liver injury (DILI) cases and the link observed by genome-wide association studies (GWASs) of certain human leucocyte antigen (HLA) alleles with DILI due to specific drugs support the c

Externí odkaz: https://doaj.org/article/376a91ad0efd4cadb235fdb15eb60000

A new framework for advancing in drug‐induced liver injury research. The Prospective European DILI Registry.

Autor: Björnsson, Einar S.^1,2 (AUTHOR), Stephens, Camilla^3,4 (AUTHOR), Atallah, Edmond^5,6 (AUTHOR), Robles‐Diaz, Mercedes^3,4 (AUTHOR), Alvarez‐Alvarez, Ismael^3,4 (AUTHOR), Gerbes, Alexander⁷ (AUTHOR), Weber, Sabine⁷ (AUTHOR), Stirnimann, Guido⁸ (AUTHOR), Kullak‐Ublick, Gerd⁹ (AUTHOR), Cortez‐Pinto, Helena¹⁰ (AUTHOR), Grove, Jane I.^5,6 (AUTHOR), Lucena, M. Isabel^3,4 (AUTHOR), Andrade, Raul J.^3,4 (AUTHOR) andrade@uma.es, Aithal, Guruprasad P.^5,6 (AUTHOR)

Publikováno v: Liver International. Jan2023, Vol. 43 Issue 1, p115-126. 12p. 8 Charts.