Zobrazeno 1 - 10 of 42 pro vyhledávání: '"Alejandro Carabe"'
1
Akademický článek
Microdosimetry and Dose-Averaged LET Calculations of Protons in Liquid Water: A Novel Geant4-DNA Application
Autor: Anna Baratto-Roldán, Alejandro Bertolet, Giorgio Baiocco, Alejandro Carabe, Miguel Antonio Cortés-Giraldo
Publikováno v: Frontiers in Physics, Vol 9 (2021)
The spatial distribution of energy deposition events is an essential aspect in the determination of the radiobiological effects of ionizing radiation at the cellular level. Microdosimetry provides a theoretical framework for the description of these
Externí odkaz: https://doaj.org/article/15afc2bce0cc4422935585e26570bb89
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2
Akademický článek
Modelling Dose Effects from Space Irradiations: Combination of High-LET and Low-LET Radiations with a Modified Microdosimetric Kinetic Model
Autor: Alejandro Bertolet, Alejandro Carabe
Publikováno v: Life, Vol 10, Iss 9, p 161 (2020)
The Microdosimetric Kinetic Model (MKM) to predict the effects of ionizing radiation on cell colonies is studied and reformulated for the case of high-linear energy transfer (LET) radiations with a low dose. When the number of radiation events happen
Externí odkaz: https://doaj.org/article/a199175f85804f1c93aaefa2d55fb286
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3
Akademický článek
Broad-spectrum antibiotic or G-CSF as potential countermeasures for impaired control of bacterial infection associated with an SPE exposure during spaceflight.
Autor: Minghong Li, Veronica Holmes, Houping Ni, Jenine K Sanzari, Ana L Romero-Weaver, Liyong Lin, Alejandro Carabe-Fernandez, Eric S Diffenderfer, Ann R Kennedy, Drew Weissman
Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120126 (2015)
A major risk for astronauts during prolonged space flight is infection as a result of the combined effects of microgravity, situational and confinement stress, alterations in food intake, altered circadian rhythm, and radiation that can significantly
Externí odkaz: https://doaj.org/article/1d2423452a684acdbf4bda9c1260efb0
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4
Akademický článek
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6
Correlation of LET With MRI Changes in Brain and Potential Implications for Normal Tissue Complication Probability for Patients With Meningioma Treated With Pencil Beam Scanning Proton Therapy
Autor: Alejandro Carabe, Christine E. Hill-Kayser, A. Bertolet, David J. Carlson, Michelle Alonso-Basanta, Robert A. Lustig, Ramin Abolfath
Publikováno v: International journal of radiation oncology, biology, physics. 112(1)
Purpose This study aimed to investigate the correlation between imaging changes in brain normal tissue and the spatial distribution of linear energy transfer (LET) for a cohort of patients with meningioma treated with scanned proton beams. Then, assu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993e649b513198b0c86491e442d31444
https://pubmed.ncbi.nlm.nih.gov/34425196
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8
Proton monoenergetic arc therapy (PMAT) to enhance LETd within the target
Autor: Alejandro Carabe, A. Bertolet
Publikováno v: Physics in medicine and biology. 65(16)
We show the performance and feasibility of a proton arc technique so-called proton monoenergetic arc therapy (PMAT). Monoenergetic partial arcs are selected to place spots at the middle of a target and its potential to enhance the dose-averaged linea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b6d3aeec169cb7000c850f357a7e2f
https://pubmed.ncbi.nlm.nih.gov/32428896
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9
A kernel‐based algorithm for the spectral fluence of clinical proton beams to calculate dose‐averaged LET and other dosimetric quantities of interest
Autor: Kevin Souris, M. A. Cortés-Giraldo, Alejandro Carabe, A. Bertolet
Publikováno v: Medical Physics, Vol. 47, no. 6, p. 2495-2505 (2020)
Purpose To introduce a new analytical methodology to calculate quantities of interest in particle radiotherapy inside the treatment planning system. Models are proposed to calculate dose-averaged LET (LETd) in proton radiotherapy. Material and method
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db95fa4331150dae76ae21025fadd772
https://hdl.handle.net/2078.1/236342
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10
Experimental Validation of an Analytical Microdosimetric Model Based on Geant4-DNA Simulations by Using a Silicon-based Microdosimeter
Autor: A. Bertolet, C. Fleta, Alejandro Carabe, A.D. Harken, Manuel Lozano, M. A. Cortés-Giraldo, Consuelo Guardiola, Anna Baratto-Roldan, V. Grilj
Publikováno v: Radiation Physics and Chemistry
Radiation Physics and Chemistry, Elsevier, 2020, pp.109060. ⟨10.1016/j.radphyschem.2020.109060⟩
Radiat Phys Chem Oxf Engl 1993
Purpose: To study the agreement between proton microdosimetric distributions measured with a silicon-based cylindrical microdosimeter and a previously published analytical microdosimetric model based on Geant4-DNA in-water Monte Carlo simulations for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eadd84c3cbb3c94ab0914e5fdcb6207
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