Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alejandro C. Rodriguez"'
Autor:
Armando Estrada, Alejandro C. Rodriguez, Georgialina Rodriguez, Alice H. Grant, Yoshira M. Ayala-Marin, Amy J. Arrieta, Robert A. Kirken
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract T-cell activation and cellular expansion by common gamma chain cytokines such as Interleukin-2 is necessary for adaptive immunity. However, when unregulated these same pathways promote pathologies ranging from autoimmune disorders to cancer.
Externí odkaz:
https://doaj.org/article/9512cc6ef415433aa641845f6ef594ca
Autor:
Alice H. Grant, Alejandro C. Rodriguez, Omar J. Rodriguez Moncivais, Shengjie Sun, Lin Li, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6805 (2023)
Overactive Janus kinases (JAKs) are known to drive leukemia, making them well-suited targets for treatment. We sought to identify new JAK-activating mutations and instead found a JAK1-inactivating pseudokinase mutation, V666G. In contrast to other ps
Externí odkaz:
https://doaj.org/article/84091df3a8aa4e85971d479748fbbef7
Autor:
Alice H. Grant, Armando Estrada, Yoshira M. Ayala-Marin, America Y. Alvidrez-Camacho, Georgialina Rodriguez, Elisa Robles-Escajeda, Denisse A. Cadena-Medina, Alejandro C. Rodriguez, Robert A. Kirken
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The positive-sense single stranded RNA virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), resulted in a global pandemic with horrendous health and economic consequences not seen in a century. At a finer scale, immunologically, many
Externí odkaz:
https://doaj.org/article/fd93700fa4a744979cbff590d5c2c9e5