Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alejandro Anton-Fernandez"'
Autor:
Eleanor K. Pickett, Abigail G. Herrmann, Jamie McQueen, Kimberly Abt, Owen Dando, Jane Tulloch, Pooja Jain, Sophie Dunnett, Sadaf Sohrabi, Maria P. Fjeldstad, Will Calkin, Leo Murison, Rosemary J. Jackson, Makis Tzioras, Anna Stevenson, Marie d’Orange, Monique Hooley, Caitlin Davies, Marti Colom-Cadena, Alejandro Anton-Fernandez, Declan King, Iris Oren, Jamie Rose, Chris-Anne McKenzie, Elizabeth Allison, Colin Smith, Oliver Hardt, Christopher M. Henstridge, Giles E. Hardingham, Tara L. Spires-Jones
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3592-3604.e5 (2019)
Summary: A key knowledge gap blocking development of effective therapeutics for Alzheimer’s disease (AD) is the lack of understanding of how amyloid beta (Aβ) peptide and pathological forms of the tau protein cooperate in causing disease phenotype
Externí odkaz:
https://doaj.org/article/5c607706c23f4f7d92a682e925ca0372
Autor:
Alejandro Antón-Fernández, Marta Roldán-Lázaro, Laura Vallés-Saiz, Jesús Ávila, Félix Hernández
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract In recent years, there has been success in partially reprogramming peripheral organ cells using cyclic Yamanaka transcription factor (YF) expression, resulting in the reversal of age-related pathologies. In the case of the brain, the effects
Externí odkaz:
https://doaj.org/article/dd6086151fdd40d980fb4c6630699948
Autor:
Javier DeFelipe, Félix Hernández, Alejandro Anton Fernandez, Guillermo Aparicio Torres, Alberto Muñoz, Jesús Avila, Silvia Tapia Gonzalez, Jesús Merchan Rubira
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The axon initial segment (AIS) is a region of the neuron that is critical for action potential generation as well as for the regulation of neural activity. This specialized structure—characterized by the expression of different types of io
Externí odkaz:
https://doaj.org/article/9430df4a28ef443491f19755fb189cad
Autor:
Alejandro Antón-Fernández, Guillermo Aparicio-Torres, Silvia Tapia, Javier DeFelipe, Alberto Muñoz
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 11-23 (2017)
The Golgi apparatus (GA) is a highly dynamic organelle, which is mainly involved in the post-translational processing and targeting of cellular proteins and which undergoes significant morphological changes in response to different physiological and
Externí odkaz:
https://doaj.org/article/616ab4756a6743a9adc5f14877ba2f35
Autor:
Colin Smith, Caitlin Davies, Rosemary J. Jackson, Makis Tzioras, Sadaf Sohrabi, Abigail G. Herrmann, Monique Hooley, Declan King, Pooja Jain, Jamie McQueen, Iris Oren, Oliver Hardt, Tara L. Spires-Jones, Christopher M. Henstridge, Eleanor K. Pickett, Anna J. Stevenson, Sophie Dunnett, Maria P. Fjeldstad, Jamie Rose, Marie d'Orange, Giles E. Hardingham, Owen Dando, Alejandro Anton-Fernandez, Martí Colom-Cadena, C. McKenzie, Jane Tulloch, Leo Murison, Will Calkin, Elizabeth Allison, Kimberly Abt
Publikováno v:
Cell Reports
Cell Reports, Vol 29, Iss 11, Pp 3592-3604.e5 (2019)
Pickett, E K, Herrmann, A G, McQueen, J, Abt, K, Dando, O, Tulloch, J, Jain, P, Dunnett, S, Sohrabi, S, Fjeldstad, M P, Calkin, W, Murison, L, Jackson, R J, Tzioras, M, Stevenson, A, d'Orange, M, Hooley, M, Davies, C, Colom Cadena, M, Anton Fernandez, A, King, D, Oren, I, Rose, J, McKenzie, C-A, Allison, E, Smith, C, Hardt, O, Henstridge, C M, Hardingham, G E & Spires-Jones, T L 2019, ' Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer’s Disease ', Cell Reports, vol. 29, no. 11, pp. 3592-3604.E5 . https://doi.org/10.1016/j.celrep.2019.11.044
Cell Reports, Vol 29, Iss 11, Pp 3592-3604.e5 (2019)
Pickett, E K, Herrmann, A G, McQueen, J, Abt, K, Dando, O, Tulloch, J, Jain, P, Dunnett, S, Sohrabi, S, Fjeldstad, M P, Calkin, W, Murison, L, Jackson, R J, Tzioras, M, Stevenson, A, d'Orange, M, Hooley, M, Davies, C, Colom Cadena, M, Anton Fernandez, A, King, D, Oren, I, Rose, J, McKenzie, C-A, Allison, E, Smith, C, Hardt, O, Henstridge, C M, Hardingham, G E & Spires-Jones, T L 2019, ' Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer’s Disease ', Cell Reports, vol. 29, no. 11, pp. 3592-3604.E5 . https://doi.org/10.1016/j.celrep.2019.11.044
Summary A key knowledge gap blocking development of effective therapeutics for Alzheimer’s disease (AD) is the lack of understanding of how amyloid beta (Aβ) peptide and pathological forms of the tau protein cooperate in causing disease phenotypes