Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alejandro Andrade-Vicenty"'
Autor:
Keerat Kaur, Piero Anversa, Polina Goichberg, Leonard M. Eisenberg, Khaled Qanud, John G. Edwards, Giulia Borghetti, Annarosa Leri, Alejandro Andrade-Vicenty, Carol A. Eisenberg, Marcello Rota, Mriganka Nerkar, Andrea Sorrentino, Sergio Signore, Thomas H. Hintze, Dong Sun, Jason T. Jacobson
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 314:H68-H81
Notch receptor signaling is active during cardiac development and silenced in myocytes after birth. Conversely, outward K+Kv currents progressively appear in postnatal myocytes leading to shortening of the action potential (AP) and acquisition of the
Autor:
Jessica R Dorilio, Heather A. O'Malley, Chaoyu Sun, Daniel O Cervantes, Dong Sun, Lori L. Isom, Alejandro Andrade-Vicenty, Eleonora Cianflone, Govindaiah Vinukonda, Marcello Rota, Jillian Pope, Saketh Anand, Jason T. Jacobson, Antonio Cannatà, Thomas H. Hintze
Publikováno v:
Circulation Research. 125
Aging in experimental animals is coupled with protracted electrical recovery of the heart and increased late Na + current (I NaL ) in cardiomyocytes. These electrophysiological alterations are coupled with impaired cardiac relaxation, raising the pos
Autor:
Marcello Rota, Dong Sun, Thomas H. Hintze, Heather A. O'Malley, Saketh Anand, Chaoyu Sun, Lori L. Isom, Daniel O Cervantes, Alejandro Andrade-Vicenty
Publikováno v:
Circulation. 138
The late Na + current has emerged as a therapeutic target for conditions characterized by depressed diastolic function, but whether enhanced Na + fluxes in cardiomyocytes interfere with cellular and myocardial relaxation remain to be clarified. For t