Association of BRCA1 germline mutations in young onset triple-negative breast cancer (TNBC)

Autor: Javier Godino, María-Teresa Calvo, I. Pajares, María-Dolores Miramar, Gemma Llort, Elena Aguirre, Berta Saez, M. Moros, Isabel Chirivella, T. Ramón y Cajal, Carmen Yagüe, S. Ramón y Cajal, Enrique Lerma, Enrique Lastra, Alejandro Tres, J. Balmaña, Luis Robles, Pedro Pérez-Segura, A. Arcusa, N. Bosch, Maria Vidal, P. Astier, Raquel Andrés

Publikováno v: CLINICAL & TRANSLATIONAL ONCOLOGY
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Clinical & Translational Oncology
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau

BRCA1-associated breast cancers have been associated to a triple-negative phenotype. The prevalence of BRCA1 germline mutations in young onset TNBC based on informativeness of family history has not been reported. From January 2008 to May 2009 were c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c716902f3884258fcc920950342301f
https://doi.org/10.1007/s12094-013-1070-9

Controlled Cell Death by Magnetic Hyperthermia: Effects of Exposure Time, Field Amplitude, and Nanoparticle Concentration

Autor: M. R. Ibarra, Gerardo F. Goya, Laura Asín, Alejandro Tres

Publikováno v: Pharmaceutical Research. 29:1319-1327

To investigate the effects of alternating magnetic fields (AMF) on the death rate of dendritic cells (DCs) loaded with magnetic nanoparticles (MNPs) as heating agents. AMF exposure time and amplitude as well as the MNPs concentration were screened to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7c7c434289484b1a48036c3c55c335
https://doi.org/10.1007/s11095-012-0710-z

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

Autor: Donghui Kan, Jack A. Schalken, Hafsteinn Saemundsson, Sebastian Navarrete, Onno van Hooij, Bjarni A. Agnarsson, D. Timothy Bishop, Gunnar Steineck, Johan Hansson, Rafn Ragnarsson, Thorunn Rafnar, Halla Skuladottir, Alejandro Tres, Eirikur Jonsson, Katja K H Aben, Eliane Kellen, Augustine Kong, Rafael Botella-Estrada, René A Termeer, Javier Banzo, Sigurborg Matthiasdottir, Henricus F. M. van der Heijden, Margret Jakobsdottir, Anna Salvarsdottir, Jose I. Mayordomo, Stefano Porru, Bardur Sigurgeirsson, Hafdis T. Helgadottir, Annika Lindblom, Giuseppe Matullo, Asgeir Sigurdsson, Gudmundur V. Einarsson, Frank Geller, Daniel F. Gudbjartsson, William J. Catalona, Steinunn Thorlacius, Rosa B. Barkardottir, Anne E. Kiltie, Rajesh Kumar, Unnur Thorsteinsdottir, Tomas Gudbjartsson, Maurice P. Zeegers, Berta Saez, Lambertus A. Kiemeney, Margret Asgeirsdottir, Helgi J Isaksson, Kari T. Kristinsson, Peter Rudnai, Jón Ólafsson, Steinn Jonsson, Kristin Thorisdottir, Gisli Masson, Petra J. de Verdier, Femmie de Vegt, Karl Olafsson, Paolo Vineis, Kvetoslava Koppova, Veronica Höiom, Hans J Smit, Jeffrey R. Gulcher, Silvia Polidoro, Thorvaldur Jonsson, Eduardo Nagore, Thorarinn Blondal, Thorgeir E. Thorgeirsson, Kristrun R. Benediktsdottir, Hjordis Bjarnason, Michael L. Frigge, Maria Vidal, Steinunn G Sveinsdottir, Raquel Andrés, Egbert Oosterwijk, Frank Buntinx, Gudmar Thorleifsson, Patrick Sulem, Pablo Juberías, Simon N. Stacey, Eugene Gurzau, Marcello Campagna, Kari Stefansson, Kristleifur Kristjansson, Ana Ferrer, Dolores Isla, Julius Gudmundsson, Kari Hemminki

Publikováno v: Nature Genetics, 41, 221-7
Nature Genetics, 41, 2, pp. 221-7
Nature Genetics, 41(2), 221-7. Nature Publishing Group

Contains fulltext : 81560.pdf (Publisher’s version ) (Closed access) The common sequence variants that have recently been associated with cancer risk are particular to a single cancer type or at most two. Following up on our genome-wide scan of bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886121aff79f0dc8716a2f6b2fc229a6
https://doi.org/10.1038/ng.296

Prognostic role of circulating melanoma cells detected by reverse transcriptase-polymerase chain reaction for tyrosinase mRNA in patients with melanoma

Autor: Carmen Visus, L. Murillo, María José Martínez-Lorenzo, Clara Diestre, Berta Sáez-Gutierrez, Alejandro Tres, Pilar Astier, Luis Larrad, Raquel Andrés, Jose I. Mayordomo, Javier Godino, Ivan Marcos, Francisco J Carapeto-Marquez de Prado

Publikováno v: Melanoma Research. 17:83-89

A need for factors predictive of prognosis is present in patients who are diagnosed with malignant melanoma. The detection of circulating melanoma cells by reverse transcriptase-polymerase chain reaction for tyrosinase mRNA is a possible negative pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab5ffe1dfd308462b133649d2d5668b
https://doi.org/10.1097/cmr.0b013e3280a60878

Prognostic Value of Serum S-100B in Malignant Melanoma

Autor: Raquel Andrés, Pedro Zaballos, A. Saenz, Luis Elosegui, Pilar Escudero, Dolores Isla, Alejandro Tres, Elena Filipovich, E. Polo, Javier Rodino, Jose I. Mayordomo

Publikováno v: Scopus-Elsevier

Aims and Background Although there is no established tumor marker of proven value for patients with melanoma, high serum levels of S-100B protein have been found in patients with melanoma and distant metastases. This study was performed to assess the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e971c291205edce8b5a99a4e21b5b6c
https://doi.org/10.1177/030089160409000613