Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Alejandra Palomino-Antolín"'
Autor:
Melania Guerrero-Hue, Mercedes Vallejo-Mudarra, Cristina García-Caballero, Gina Marcela Córdoba-David, Alejandra Palomino-Antolín, Carmen Herencia, Beatriz Vendrell-Casana, Alfonso Rubio-Navarro, Jesús Egido, Luis Miguel Blanco-Colio, Juan Antonio Moreno
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115925- (2023)
Background: Rhabdomyolysis is a severe clinical syndrome associated to acute kidney injury (AKI) and chronic kidney disease (CKD). TWEAK/Fn14 signaling axis regulates renal inflammation and tubular cell death. However, the functional role of TWEAK/Fn
Externí odkaz:
https://doaj.org/article/a38a6f4bb8ce421fb7c661f8c5c2adac
Autor:
Alejandra Palomino-Antolín, Céline Decouty-Pérez, Víctor Farré-Alins, Paloma Narros-Fernández, Ana Belen Lopez-Rodriguez, María Álvarez-Rubal, Inés Valencia, Francisco López-Muñoz, Eva Ramos, Antonio Cuadrado, Ana I. Casas, Alejandro Romero, Javier Egea
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1729 (2023)
The role of inflammation and immunity in the pathomechanism of neurodegenerative diseases has become increasingly relevant within the past few years. In this context, the NOD-like receptor protein 3 (NLRP3) inflammasome plays a crucial role in the ac
Externí odkaz:
https://doaj.org/article/552434a0330b4ac5ab6087e7cbc3bf4f
Autor:
Ana Belen Lopez-Rodriguez, Céline Decouty-Perez, Victor Farré-Alins, Alejandra Palomino-Antolín, Paloma Narros-Fernández, Javier Egea
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1550 (2022)
Despite the numerous research studies on traumatic brain injury (TBI), many physiopathologic mechanisms remain unknown. TBI is a complex process, in which neuroinflammation and glial cells play an important role in exerting a functional immune and da
Externí odkaz:
https://doaj.org/article/3f3420d777764e838c872ebada56450d
Autor:
Melania Guerrero-Hue, Alfonso Rubio-Navarro, Ángel Sevillano, Claudia Yuste, Eduardo Gutiérrez, Alejandra Palomino-Antolín, Elena Román, Manuel Praga, Jesús Egido, Juan Antonio Moreno
Publikováno v:
Nefrología, Vol 38, Iss 1, Pp 13-26 (2018)
La hemoglobina y la mioglobina son hemoproteínas que juegan un papel fundamental en el organismo ya que participan en el transporte de oxígeno. Sin embargo, debido a su estructura química, estas moléculas pueden ejercer efectos deletéreos cuando
Externí odkaz:
https://doaj.org/article/07ab050ab12f4b47accfcbbb65b2f559
Autor:
Melania Guerrero-Hue, Alfonso Rubio-Navarro, Ángel Sevillano, Claudia Yuste, Eduardo Gutiérrez, Alejandra Palomino-Antolín, Elena Román, Manuel Praga, Jesús Egido, Juan Antonio Moreno
Publikováno v:
Nefrología (English Edition), Vol 38, Iss 1, Pp 13-26 (2018)
Haemoglobin and myoglobin are haem proteins that play a key role as they help transport oxygen around the body. However, because of their chemical structure, these molecules can exert harmful effects when they are released massively into the bloodstr
Externí odkaz:
https://doaj.org/article/d0b8f204dfc844bf9f3ac017ea81710b
Autor:
José M. Alonso, Alejandro Escobar-Peso, Alejandra Palomino-Antolín, Daniel Diez-Iriepa, Mourad Chioua, Emma Martínez-Alonso, Isabel Iriepa, Javier Egea, Alberto Alcázar, José Marco-Contelles
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 861 (2021)
Cerebrovascular diseases such as ischemic stroke are known to exacerbate dementia caused by neurodegenerative pathologies such as Alzheimer’s disease (AD). Besides, the increasing number of patients surviving stroke makes it necessary to treat the
Externí odkaz:
https://doaj.org/article/4cea36c23b4c4e4c8f6cfe07236bf2f7
Autor:
Víctor Farré-Alins, Alejandra Palomino-Antolín, Paloma Narros-Fernández, Ana Belen Lopez-Rodriguez, Céline Decouty-Perez, Alicia Muñoz-Montero, Jorge Zamorano-Fernández, Beatriz Mansilla-Fernández, Javier Giner-García, Pablo García-Feijoo, Miguel Sáez-Alegre, Alexis J. Palpán-Flores, José María Roda-Frade, Cristina S. Carabias, Juliana M. Rosa, Belén Civantos-Martín, Santiago Yus-Teruel, Luis Gandía, Alfonso Lagares, Borja J. Hernández-García, Javier Egea
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 599 (2021)
Traumatic brain injury (TBI) is one of the leading causes of mortality and disability worldwide without any validated biomarker or set of biomarkers to help the diagnosis and evaluation of the evolution/prognosis of TBI patients. To achieve this aim,
Externí odkaz:
https://doaj.org/article/be05805fe34f48ddb786627ce1bc222f
Autor:
Víctor Farré-Alins, Paloma Narros-Fernández, Alejandra Palomino-Antolín, Céline Decouty-Pérez, Ana Belen Lopez-Rodriguez, Esther Parada, Alicia Muñoz-Montero, Vanessa Gómez-Rangel, Francisco López-Muñoz, Eva Ramos, Águeda González-Rodríguez, Luis Gandía, Alejandro Romero, Javier Egea
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1299 (2020)
Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release. In this work, we have
Externí odkaz:
https://doaj.org/article/7f5db3adb4c44b268e7337f0de0bc644
Autor:
Melania Guerrero-Hue, Sandra Rayego-Mateos, Cristina Vázquez-Carballo, Alejandra Palomino-Antolín, Cristina García-Caballero, Lucas Opazo-Rios, José Luis Morgado-Pascual, Carmen Herencia, Sebastián Mas, Alberto Ortiz, Alfonso Rubio-Navarro, Javier Egea, José Manuel Villalba, Jesús Egido, Juan Antonio Moreno
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 39 (2020)
Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. However, therapies to slow or
Externí odkaz:
https://doaj.org/article/1b7bfe55885f4191b65646457b3e8d96
Autor:
Eva Ramos, Alejandra Palomino-Antolín, Manuela Bartolini, Isabel Iriepa, Ignacio Moraleda, Daniel Diez-Iriepa, Abdelouahid Samadi, Carol V. Cortina, Mourad Chioua, Javier Egea, Alejandro Romero, José Marco-Contelles
Publikováno v:
Molecules, Vol 24, Iss 8, p 1503 (2019)
We report the synthesis and relevant pharmacological properties of the quinoxalinetacrine (QT) hybrid QT78 in a project targeted to identify new non-hepatotoxic tacrine derivatives for Alzheimer’s disease therapy. We have found that QT78 is less to
Externí odkaz:
https://doaj.org/article/fb8b554486d4413dadc90ccd3cac5f5e