Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alejandra M, Petrilli"'
Autor:
Anna Casu, Yury O. Nunez Lopez, Gongxin Yu, Christopher Clifford, Anika Bilal, Alejandra M. Petrilli, Heather Cornnell, Elvis Alvarez Carnero, Ananya Bhatheja, Karen D. Corbin, Anton Iliuk, David M. Maahs, Richard E. Pratley
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionThere are no validated clinical or laboratory biomarkers to identify and differentiate endotypes of type 1 diabetes (T1D) or the risk of progression to chronic complications. Extracellular vesicles (EVs) have been studied as biomarkers in
Externí odkaz:
https://doaj.org/article/8c965ea96b4345fca91e6b64f3d26101
Autor:
Yury O. Nunez Lopez, Anna Casu, Zuzana Kovacova, Alejandra M. Petrilli, Olga Sideleva, William G. Tharp, Richard E. Pratley
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Pioglitazone, a PPARγ agonist, is used to treat type 2 diabetes (T2D). PPARγ is highly expressed in adipose tissue (AT), however the effects of pioglitazone to improve insulin sensitivity are also evident in other tissues and PPARγ agonism has bee
Externí odkaz:
https://doaj.org/article/fdfc0e0b0b624c89a1fbb9eb2320c5cf
Autor:
Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, Marc Ferrer, Steven P Angus, Eric Hawley, Alejandra M Petrilli, Roberta L Beauchamp, Lars Björn Riecken, Serkan Erdin, Ming Poi, Jie Huang, Waylan K Bessler, Xiaohu Zhang, Rajarshi Guha, Craig Thomas, Sarah S Burns, Thomas S K Gilbert, Li Jiang, Xiaohong Li, Qingbo Lu, Jin Yuan, Yongzheng He, Shelley A H Dixon, Andrea Masters, David R Jones, Charles W Yates, Stephen J Haggarty, Salvatore La Rosa, D Bradley Welling, Anat O Stemmer-Rachamimov, Scott R Plotkin, James F Gusella, Justin Guinney, Helen Morrison, Vijaya Ramesh, Cristina Fernandez-Valle, Gary L Johnson, Jaishri O Blakeley, D Wade Clapp, Synodos for NF2 Consortium
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0252048 (2021)
Neurofibromatosis Type 2 (NF2) is an autosomal dominant genetic syndrome caused by mutations in the NF2 tumor suppressor gene resulting in multiple schwannomas and meningiomas. There are no FDA approved therapies for these tumors and their relentless
Externí odkaz:
https://doaj.org/article/d5cdd322a442449ebaffcbfad82ea6a3
Autor:
Synodos for NF2 Consortium, Robert Allaway, Steve P Angus, Roberta L Beauchamp, Jaishri O Blakeley, Marga Bott, Sarah S Burns, Annemarie Carlstedt, Long-Sheng Chang, Xin Chen, D Wade Clapp, Patrick A Desouza, Serkan Erdin, Cristina Fernandez-Valle, Justin Guinney, James F Gusella, Stephen J Haggarty, Gary L Johnson, Salvatore La Rosa, Helen Morrison, Alejandra M Petrilli, Scott R Plotkin, Abhishek Pratap, Vijaya Ramesh, Noah Sciaky, Anat Stemmer-Rachamimov, Tim J Stuhlmiller, Michael E Talkowski, D Bradley Welling, Charles W Yates, Jon S Zawistowski, Wen-Ning Zhao
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197350 (2018)
Neurofibromatosis 2 (NF2) is a rare tumor suppressor syndrome that manifests with multiple schwannomas and meningiomas. There are no effective drug therapies for these benign tumors and conventional therapies have limited efficacy. Various model syst
Externí odkaz:
https://doaj.org/article/9827869b05b5455bb1789d9f8c1987f8
Autor:
Anna Casu, Yury O. Nunez Lopez, Gongxin Yu, Christopher Clifford, Anika Bilal, Alejandra M. Petrilli, Heather Cornnell, Karen Corbin, Anton Iliuk, David Maahs, Elizabeth J. Mayer-Davis, Richard E. Pratley
Type 1 diabetes (T1D) is a heterogeneous disease with a slower evolution in individuals diagnosed at older ages. There are no validated clinical or laboratory biomarkers to predict the rate of insulin secretion decline either before or after the clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a141e893a367f2fe44075d97b3671559
https://doi.org/10.1101/2022.03.10.22272207
https://doi.org/10.1101/2022.03.10.22272207
Autor:
Anton Iliuk, Richard E. Pratley, Alejandra M Petrilli, Yury O. Nunez Lopez, Carley Glass, Anna Casu
The purpose of this study was to characterize the proteomic and phosphoproteomic profiles of circulating extracellular vesicles (EVs) from people with normal glucose tolerance (NGT), prediabetes (PDM), and diabetes (T2DM). Archived serum samples from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efce24e2822a445a98bada0b4ba21ad0
https://doi.org/10.1101/2021.10.31.21265724
https://doi.org/10.1101/2021.10.31.21265724
Autor:
Salvatore La Rosa, Helen Morrison, Jie Huang, Rajarshi Guha, Li Jiang, Yongzheng He, Gary L. Johnson, Steven P. Angus, Eric T. Hawley, Vijaya Ramesh, Justin Guinney, Sarah S. Burns, Jin Yuan, Roberta L. Beauchamp, Lars Björn Riecken, Cristina Fernandez-Valle, Marc Ferrer, Charles W. Yates, Serkan Erdin, Abbi Smith, Waylan K. Bessler, D. Bradley Welling, D. Wade Clapp, Shelley Dixon, Scott R. Plotkin, Ming Poi, Thomas S. K. Gilbert, Anat Stemmer-Rachamimov, Alejandra M. Petrilli, Craig J. Thomas, Xiaohong Li, Qingbo Lu, David R. Jones, James F. Gusella, Long-Sheng Chang, Andrea R. Masters, Xiaohu Zhang, Janet L. Oblinger, Jaishri O. Blakeley, Stephen J. Haggarty
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0252048 (2021)
PLoS ONE, Vol 16, Iss 7, p e0252048 (2021)
Neurofibromatosis Type 2 (NF2) is an autosomal dominant genetic syndrome caused by mutations in the NF2 tumor suppressor gene resulting in multiple schwannomas and meningiomas. There are no FDA approved therapies for these tumors and their relentless
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3305e5677c3612913a49faf5250fc4e0
http://europepmc.org/articles/PMC8282008
http://europepmc.org/articles/PMC8282008
Autor:
Stephani Klingeman Plati, D. Bradley Welling, Fred F. Telischi, Denise Yan, Alejandra M. Petrilli, Rahul Mittal, Marga Bott, Alicja J. Copik, Cristina Fernandez-Valle, Xue Zhong Liu, Olena Bracho, Bing Zou, Jeanine Garcia, Christine T. Dinh, Long-Sheng Chang
Publikováno v:
Oncotarget
// Alejandra M. Petrilli 1 , Jeanine Garcia 1 , Marga Bott 1 , Stephani Klingeman Plati 1 , Christine T. Dinh 2 , Olena R. Bracho 2 , Denise Yan 2 , Bing Zou 2 , Rahul Mittal 2 , Fred F. Telischi 2 , Xue-Zhong Liu 2 , Long-Sheng Chang 3 , D. Bradley
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e822c1e6d076e146f29d248be92f786
http://europepmc.org/articles/PMC5458238
http://europepmc.org/articles/PMC5458238
Autor:
Stephani Klingeman Plati, Denise Yan, Olena Bracho, Long-Sheng Chang, Marco Giovannini, Joanna Kirkpatrick, Marisa A. Fuse, Maria Clara Franco, Jackson Nagamoto, Helen Morrison, Fred F. Telischi, Alicja J. Copik, Rulong Shen, Cristina Fernandez-Valle, Xue Zhong Liu, Annemarie Carlstedt, Konstantin Brnjos, Jie Huang, Alejandra M. Petrilli, Jeremie Vitte, Thomas Mindos, Julia N. Soulakova, Christine T. Dinh, Juan I. Young, Rahul Mittal
Publikováno v:
Neuro-oncology, vol 21, iss 4
Background Neurofibromatosis type 2 (NF2) is a genetic tumor-predisposition disorder caused by NF2/merlin tumor suppressor gene inactivation. The hallmark of NF2 is formation of bilateral vestibular schwannomas (VS). Because merlin modulates activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ae489166e9a469edef1883c3ba0977
https://escholarship.org/uc/item/1rn637vg
https://escholarship.org/uc/item/1rn637vg
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1739
Schwannomas are benign nerve tumors that occur sporadically in the general population and in those with neurofibromatosis type 2 (NF2), a tumor predisposition genetic disorder. NF2-associated schwannomas and most sporadic schwannomas are caused by in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::761359cbbd3c264c19e3894c4d53fa93
https://pubmed.ncbi.nlm.nih.gov/29546707
https://pubmed.ncbi.nlm.nih.gov/29546707