An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model

Autor: Alejandra Gonzalez Calle, Javad Paknahad, Dimitrios Pollalis, Pragya Kosta, Biju Thomas, Ben Yi Tew, Bodour Salhia, Stan Louie, Gianluca Lazzi, Mark Humayun

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract Retinal diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are characterized by unrelenting neuronal death. However, electrical stimulation has been shown to induce neuroprotective changes in the retina cap

Externí odkaz: https://doaj.org/article/9fa01fa1d3c444e8a3ccb449cdad8b56

Polarized RPE Secretome Preserves Photoreceptors in Retinal Dystrophic RCS Rats

Autor: Humayun, Kabir Ahluwalia, Juan-Carlos Martinez-Camarillo, Biju B. Thomas, Aditya Naik, Alejandra Gonzalez-Calle, Dimitrios Pollalis, Jane Lebkowski, Sun Young Lee, Debbie Mitra, Stan G. Louie, Mark S.

Publikováno v: Cells; Volume 12; Issue 13; Pages: 1689

Retinal degenerative diseases, including age-related macular degeneration (AMD) and retinitis pigmentosa, lack effective therapies. Conventional monotherapeutic approaches fail to target the multiple affected pathways in retinal degeneration. However

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::fab0ea0e18ade29183fc1ba0135889dc

Retina-electrode interface properties and vision restoration by two generations of retinal prostheses in one patient-one in each eye

Autor: Varalakshmi Wuyyuru, Lan Yue, Mark S. Humayun, Jessy D. Dorn, Alejandra Gonzalez-Calle

Publikováno v: Journal of neural engineering. 17(2)

Objective The Argus I implant is a first-generation epiretinal prosthesis approved for an investigational clinical trial in the U.S. Its successor, the Argus II implant, has a higher electrode density for increased spatial resolution and covers a lar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8766e14d7a98f511ffa3dae74c09b98c
https://pubmed.ncbi.nlm.nih.gov/32131056

List of Contributors of Volume 3

Autor: Thomas Abell, William T. Abraham, Ali Alabbad, Adnan Al-Kaisy, Paulin Andréll, Richard Andrew McKinley, Claudia A. Angeli, Jeffrey L. Ardell, Anthony Arnold, Musa Audu, Kenneth B. Baker, Giancarlo Barolat, Jonathan Z. Baskin, Girriso F. Benderro, Maria E. Bennett, Marom Bikson, Chad E. Bouton, Una Buckley, Sandra Carvalho, James Cavuoto, John Chae, Jiande D.Z. Chen, Shuo Chen, Joshua A. Cohn, Graham H. Creasey, Christopher J. Czura, Elizabeth G. Damato, William C. de Groat, Michael J. Decker, Anthony F. DiMarco, Laura Dipietro, Roger R. Dmochowski, Michael F. Dorman, Rui V. Duarte, Dominique M. Durand, Robin Elizabeth Germany, Charles Emala, J.P. Errico, Michael Faltys, Manfred Franke, Felipe Fregni, Melanie French, Jason R. Fritz, John P. Gassler, Alejandra Gonzalez Calle, Susan J. Harkema, Magdy Hassouna, Svante Horsch, Mark S. Humayun, Jared M. Huston, Haifeng Jin, Leonardo Kapural, Melissa R. Kaufman, Kevin L. Kilgore, Jayme S. Knutson, Rudi Kobetic, Krzysztof E. Kowalski, Casey G. Kowalik, Elliot S. Krames, Jorge Leite, Yaakov A. Levine, Yanmei Li, James Loudin, Peter L. Lu, Andre G. Machado, Nathaniel S. Makowski, Sachin Malde, D. Michael Ackermann, Douglas F. Milam, Alon Y. Mogilner, Hayat M. Mousa, Megan Moynahan, Drew Murray, Peder S. Olofsson, Raymond P. Onders, P. Hunter Peckham, Laura Perryman, Fabian Piedimonte, Joshua P. Prager, Enrico Rejc, William S. Reynolds, Arun Sahai, Siamak Salavatian, Matthew A. Schiefer, Marabel Schneider, Stefan Schulte, Stephen Selkirk, Marcel Simis, Bruce Simon, Jesse Simon, Jon Snyder, Peter Staats, Kingman P. Strohl, Aurore Thibaut, Simon J. Thomson, Ronald J. Triolo, Dustin J. Tyler, Gozde Unal, Alejandra Vasquez, Timothy Wagner, Connor A. Wathen, James D. Weiland, Blake S. Wilson, Richard D. Wilson, Shukun Yao, Jieyun Yin, Ayhan Yoruk, Ralph Zitnik

Publikováno v: Neuromodulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::788b1ca65bf3f09281864c3da4fc7aca
https://doi.org/10.1016/b978-0-12-805353-9.01006-8

Evaluation of effects of electrical stimulation in the retina with optical coherence tomography

Autor: James D. Weiland, Alejandra Gonzalez-Calle

Publikováno v: EMBC

Retinal prostheses provide the capability to blind patients to detect motion and locate large objects. To avoid activating axons of passage, which can create streak-like perceptions, long pulse stimulation can be used to bypass axons and achieve foca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dce60e7e359c52aa18aa42f682f0b0c
https://doi.org/10.1109/embc.2016.7592140