Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alejandra Estepa- Fernández"'
Autor:
Araceli Lérida-Viso, Alejandra Estepa- Fernández, Ángela Morellá-Aucejo, Beatriz Lozano-Torres, María Alfonso, Juan F. Blandez, Viviana Bisbal, Pilar Sepúlveda, Alba García-Fernández, Mar Orzáez, Ramón Martínez-Máñez
Publikováno v:
Pharmacological Research, Vol 183, Iss , Pp 106356- (2022)
Many anticancer agents used in clinics induce premature senescence in healthy tissues generating accelerated aging processes and adverse side-effects in patients. Cardiotoxicity is a well-known limiting factor of anticancer treatment with doxorubicin
Externí odkaz:
https://doaj.org/article/69036e5930d14f0f8dda477cfa16e7ce
Autor:
Alejandra Estepa-Fernández
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
[ES] Esta tesis doctoral titulada "Evaluación preclínica de estrategias basadas en la senescencia para mejorar la terapia contra el cáncer" se centra en explotar la senescencia como opción terapéutica en los tratamientos contra el cáncer median
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07785d992ec85aa045d3eaf4f2a676d3
https://doi.org/10.4995/thesis/10251/188845
https://doi.org/10.4995/thesis/10251/188845
Autor:
Sandra Roche, Patricia Gaule, Deirdre Winrow, Nupur Mukherjee, Fiona O’Neill, Neil T. Conlon, Justine Meiller, Denis M. Collins, Alexandra Canonici, Mohammed Ibrahim Fawsi, Alejandra Estepa-Fernández, Stephen F. Madden, John Crown, Norma O’Donovan, Alex J. Eustace
Publikováno v:
PLOS ONE. 18:e0282512
Triple Negative Breast Cancer (TNBC), a subtype of breast cancer, has fewer successful therapeutic therapies than other types of breast cancer. Insulin-like growth factor receptor 1 (IGF1R) and the Insulin receptor (IR) are associated with poor outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7dcbcf9ddea5a1ddbdf927afcc81eba
https://doi.org/10.1371/journal.pone.0282512
https://doi.org/10.1371/journal.pone.0282512
Autor:
Alejandra Estepa-Fernández, Alba García-Fernández, Araceli Lérida-Viso, Juan F. Blandez, Irene Galiana, Félix Sancenon-Galarza, Mar Orzáez, Ramón Martínez-Máñez
Publikováno v:
Pharmacological Research. 187:106628
Triple-negative breast cancer (TNBC) is a very aggressive subtype of breast cancer with a poor prognosis and limited effective therapeutic options. Induction of senescence, arrest of cell proliferation, has been explored as an effective method to lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e51c99ae4c5a9837abf28b9acd430b
https://doi.org/10.1016/j.phrs.2022.106628
https://doi.org/10.1016/j.phrs.2022.106628
Autor:
Ramón Martínez-Máñez, Manuel Serrano, Miguel Rovira, Beatriz Lozano-Torres, Alejandra Estepa-Fernández, Mar Orzáez, Félix Sancenón
Publikováno v:
Nature Reviews Chemistry. 3:426-441
Senescence is a state of permanent cell cycle arrest. Cellular senescence can promote tissue remodelling but can negatively affect regenerative capacities of tissues and contribute to inflammation and the progression of cancer and ageing-related dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645b276fe1a05be87a350e37b4138f12
https://doi.org/10.1038/s41570-019-0108-0
https://doi.org/10.1038/s41570-019-0108-0
Autor:
Alba García-Fernández, Irene Galiana, Félix Sancenón, Paula M. Soriano-Teruel, Ángela Morellá-Aucejo, Araceli Lérida-Viso, Alejandra Estepa-Fernández, María Alfonso, Beatriz Lozano-Torres, Mar Orzáez, Ramón Martínez-Máñez
Publikováno v:
Advanced Therapeutics. 4:2100149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36dcf4ed799e81627db3320e33201952
https://doi.org/10.1002/adtp.202100149
https://doi.org/10.1002/adtp.202100149