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pro vyhledávání: '"Alejandra D. Alonso"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Tau is a cytosolic protein that has also been observed in the nucleus, where it has multiple proposed functions that are regulated by phosphorylation. However, the mechanism underlying the nuclear import of tau is unclear, as is the contribution of n
Externí odkaz:
https://doaj.org/article/e6f9823bc3cf42a2a71ccca4622e019a
Autor:
Viktoriya Morozova, Leah S. Cohen, Ali El-Hadi Makki, Alison Shur, Guillermo Pilar, Abdeslem El Idrissi, Alejandra D. Alonso
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The microtubule associated protein tau is mainly found in the cell’s cytosol but recently it was also shown in the extracellular space. In neurodegenerative diseases, like Alzheimer’s disease (AD), pathological tau spreads from neuron to neuron e
Externí odkaz:
https://doaj.org/article/51cbe79388f242f68e00cd5f3f4bb638
Autor:
Alejandra D. Alonso, Leah S. Cohen, Christopher Corbo, Viktoriya Morozova, Abdeslem ElIdrissi, Greg Phillips, Frida E. Kleiman
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Tau is a neuronal microtubule associated protein whose main biological functions are to promote microtubule self-assembly by tubulin and to stabilize those already formed. Tau also plays an important role as an axonal microtubule protein. Tau is an a
Externí odkaz:
https://doaj.org/article/22bc65e8d3224e84ba12a98ef41c97ce