Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alejandra Crespo"'
Autor:
Ana Medel-Martinez, Ana Redrado-Osta, Alejandra Crespo-Barreda, Maria Sancho-Albero, Lourdes Sánchez, Víctor Sebastián, María Pardo, Antonio de la Vieja, Pilar Martín-Duque
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 810 (2024)
Exosomes are cell-derived extracellular vesicles (EVs) with diameters between 30 and 120 nm. In recent years, several studies have evaluated the therapeutic potential of exosomes derived from different fluids due to their low immunogenicity and high
Externí odkaz:
https://doaj.org/article/648df38b04f14da78a4f6b7e63bd6cfc
Autor:
Eugenia Martin Vázquez, Nadia Cobo-Vuilleumier, Raquel Araujo Legido, Sandra Marín-Cañas, Emanuele Nola, Akaitz Dorronsoro, Lucia López Bermudo, Alejandra Crespo, Silvana Y. Romero-Zerbo, Maria García-Fernández, Alejandro Martin Montalvo, Anabel Rojas, Valentine Comaills, Francisco J. Bérmudez-Silva, Maureen Gannon, Franz Martin, Decio Eizirik, Petra I. Lorenzo, Benoit R. Gauthier
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104345- (2022)
Summary: LRH-1/NR5A2 is implicated in islet morphogenesis postnatally, and its activation using the agonist BL001 protects islets against apoptosis, reverting hyperglycemia in mouse models of Type 1 Diabetes Mellitus. Islet transcriptome profiling re
Externí odkaz:
https://doaj.org/article/8058666987f74aa8a44031e045ebfaf8
Autor:
Antonio Campos-Caro, Eduardo García Fuentes, Francisco Javier Bermúdez-Silva, Nadia Cobo-Vuilleumier, Petra I. Lorenzo, Christian Claude Lachaud, Benoit R. Gauthier, Valentine Comaills, Esther Fuente-Martin, Jose C. Reyes, Alejandro Martin-Montalvo, Alejandra Crespo Barreda, José A Guerrero Martínez, Sabrina Rivero Canalejo, Jesús Ángel Pérez-Cabello, Franz Martín, Manuel Álvarez Dolado, José Manuel Mellado-Gil, Eugenia Martin Vázquez, Gemma Rojo-Martínez, Silvana Y. Romero-Zerbo, David Pozo, Jaime M. Franco, Manuel Aguilar-Diosdado, Livia López-Noriega
Publikováno v:
Theranostics
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
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Rationale: We recently demonstrated that the Metabesity factor HMG20A regulates islet beta-cell functional maturity and adaptation to physiological stress such as pregnancy and pre-diabetes. HMG20A also dictates central nervous system (CNS) developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353d6c4b8b7acf4f3e6f9f951fd6d22d
https://doi.org/10.7150/thno.57237
https://doi.org/10.7150/thno.57237
Autor:
Eugenia, Martin Vázquez, Nadia, Cobo-Vuilleumier, Raquel, Araujo Legido, Sandra, Marín-Cañas, Emanuele, Nola, Akaitz, Dorronsoro, Lucia, López Bermudo, Alejandra, Crespo, Silvana Y, Romero-Zerbo, Maria, García-Fernández, Alejandro, Martin Montalvo, Anabel, Rojas, Valentine, Comaills, Francisco J, Bérmudez-Silva, Maureen, Gannon, Franz, Martin, Decio, Eizirik, Petra I, Lorenzo, Benoit R, Gauthier
Publikováno v:
iScience. 25(5)
LRH-1/NR5A2 is implicated in islet morphogenesis postnatally, and its activation using the agonist BL001 protects islets against apoptosis, reverting hyperglycemia in mouse models of Type 1 Diabetes Mellitus. Islet transcriptome profiling revealed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5bbd00ba6041914996c21743c543637
https://pubmed.ncbi.nlm.nih.gov/35602948
https://pubmed.ncbi.nlm.nih.gov/35602948
Autor:
Nadia Cobo-Vuilleumier, Raquel Araujo Legido, Petra I. Lorenzo, Lucia López Bermudo, Valentine Comaills, Maureen Gannon, Anabel Rojas, Jorge Ferrer, Eugenia Martin Vázquez, Franz Martín, Emanuele Nola, Francisco Javier Bermúdez-Silva, Alejandro Martin Montalvo, Benoit R. Gauthier, Alejandra Crespo, Silvana Y. Romero-Zerbo, María García-Fernández
We have previously described a role of LRH-1/NR5A2 in islet morphogenesis during postnatal development and reported that the treatment with BL001, an agonist of LRH-1/NR5A2, protects islets against-stress induced apoptosis and reverts hyperglycemia i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f63162b6fdcd416309a538f23fcf848
https://doi.org/10.1101/2021.11.02.466895
https://doi.org/10.1101/2021.11.02.466895
Autor:
Nuria Lafuente-Gómez, Marco Cordani, Pilar Martin-Duque, Alejandra Crespo-Barreda, Ana Latorre, Álvaro Somoza, Alfonso Latorre, Milagros Castellanos, Ciro Rodriguez Diaz, Mercedes Lecea
Publikováno v:
Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
instname
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Uveal melanoma (UM) is an intraocular tumor which is almost lethal at the metastatic stage due to the lack of effective treatments. In this regard, we have developed an albumin-based nanostructure (ABN) containing AZD8055 (ABN-AZD), which is a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dd4309db4ff90d2307e461e76be7d6
http://hdl.handle.net/20.500.12614/2610
http://hdl.handle.net/20.500.12614/2610
Autor:
Manuel Arruebo, Victor Sebastian, Silvia Irusta, Maria del Mar Encabo-Berzosa, María Sancho-Albero, Jesus Santamaria, Alejandra Crespo, Pilar Martin-Duque, Vanesa Andreu
Publikováno v:
Nanoscale. 9(28)
Mesenchymal stem cells (MSCs) not only can be differentiated into different cell types but also have tropism towards injured or inflamed tissues serving as repair cells. Here we have demonstrated that MSCs containing gold nanoparticles (GNPs) whose s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212575d0bc5d665d2cb532c2d4af151b
https://pubmed.ncbi.nlm.nih.gov/28650026
https://pubmed.ncbi.nlm.nih.gov/28650026
Autor:
Nora Kogan, Mercedes Hassan, Elena Chaparro, Simon Eduardo Gusis, Rosana Veira, Alejandra Crespo
Publikováno v:
Psoriasis Forum. :23-30
Objective To assess whether psoriasis comorbidities modify the disease. Material and Methods In 170 patients with psoriasis, we considered the following comorbidities: hypertension, metabolic syndrome, diabetes, dyslipidemia, overweight, cardiovascul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6670470004600a427d554b145580ab7
https://doi.org/10.1177/247553031016a00305
https://doi.org/10.1177/247553031016a00305
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