Limited expression of TLR9 on T cells and its functional consequences in patients with nonalcoholic fatty liver disease

Autor: Nadia Soledad Alegre, Cecilia Claudia Garcia, Luis Ariel Billordo, Beatriz Ameigeiras, Daniel Poncino, Javier Benavides, Luis Colombato, Alejandra Claudia Cherñavsky

Publikováno v: Clinical and Molecular Hepatology, Vol 26, Iss 2, Pp 216-226 (2020)

Background/Aims Toll-like receptors (TLRs) modulate T cell responses in diverse diseases. Co-stimulation of T cell activation via TLR9 induces production of interferon gamma (IFN-γ), priming of which is critical for differentiation of pro-inflammato

Externí odkaz: https://doaj.org/article/a48097d09cea424991158c1a9ee86d13

The IL-1 gene family and bone involvement in celiac disease

Autor: J.B.A. Crusius, María de Lourdes Moreno, J. C. Bai, Eduardo Mauriño, Alejandra Claudia Cherñavsky, Alicia Sambuelli, Emilia Sugai, Horacio Vázquez, Amado Salvador Peña

Publikováno v: Moreno, M L, Crusius, J B A, Chernavsky, A, Sugai, E, Sambuelli, A, Vazquez, H, Maurino, E, Pena, A S & Bai, J C 2005, ' The IL-1 gene family and bone involvement in celiac disease ', Immunogenetics, vol. 57, no. 8, pp. 618-620 . https://doi.org/10.1007/s00251-005-0033-x
Immunogenetics, 57(8), 618-620. Springer Verlag

Celiac disease (CD) is associated with decreased bone mineral mass. Its pathogenesis is multifactorial since both systemic and local mechanisms may play a role. Our objective was to determine whether single-nucleotide polymorphisms in genes encoding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99d5e1fdab1a052d2bf72e45d895017
https://link.springer.com/article/10.1007/s00251-005-0033-x