Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alejandra Aranguiz"'
Autor:
Rodrigo A. Quintanilla, Carola Tapia-Monsalves, Erick H. Vergara, María José Pérez, Alejandra Aranguiz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Mitochondria are highly specialized organelles essential for the synapse, and their impairment contributes to the neurodegeneration in Alzheimer’s disease (AD). Previously, we studied the role of caspase-3–cleaved tau in mitochondrial dysfunction
Externí odkaz:
https://doaj.org/article/d967ec8aff044517a8f7d4f1338203dc
Autor:
María José Pérez, Daniela P. Ponce, Alejandra Aranguiz, Maria I. Behrens, Rodrigo A. Quintanilla
Publikováno v:
Redox Biology, Vol 19, Iss , Pp 290-300 (2018)
In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a neurodegenerative disorder, mitochondrial damage is also present in patients’ peripheral tissues
Externí odkaz:
https://doaj.org/article/1f890722cbdd4813825f70a091d45a84
Autor:
Carola Tapia-Monsalves, María José Pérez, Alejandra Aranguiz, Rodrigo A. Quintanilla, Gloria Mendez
Publikováno v:
Neurotoxicity research. 38(2)
Excessive alcohol intake affects hippocampal function and neuronal communication through oxidative stress and mitochondrial impairment. Previous studies have suggested that the melanocortin system (MCS) plays an essential role in alcohol consumption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349d3e91d3a74769831285047d4e122c
https://pubmed.ncbi.nlm.nih.gov/32378055
https://pubmed.ncbi.nlm.nih.gov/32378055
Autor:
Rodrigo A. Quintanilla, María José Pérez, Daniela P. Ponce, Alejandra Aranguiz, Maria I. Behrens
Publikováno v:
Redox Biology, Vol 19, Iss, Pp 290-300 (2018)
Redox Biology
Redox Biology
In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a neurodegenerative disorder, mitochondrial damage is also present in patients’ peripheral tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833f7142687d8a3e757b00044c1e2264
https://doi.org/10.1016/j.redox.2018.09.001
https://doi.org/10.1016/j.redox.2018.09.001
Publikováno v:
Redox Biology, Vol 18, Iss, Pp 279-294 (2018)
Redox Biology
Redox Biology
Tau is a key protein for microtubule stability; however, post-translationally modified tau contributes to neurodegenerative diseases by forming tau aggregates in the neurons. Previous reports from our group and others have shown that pathological for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2f553ad0342b33fd6d09fcde65ae42
https://doi.org/10.1016/j.redox.2018.07.010
https://doi.org/10.1016/j.redox.2018.07.010
Autor:
Francisco Canelo, María José Pérez, Rocío Loyola, Carola Tapia-Monsalves, Alejandra Aranguiz, Cesar Osorio-Fuentealba, Rodrigo A. Quintanilla
Publikováno v:
Neuropharmacology. 171:108100
Acute ethanol treatment induces neurodegeneration in cultured neurons and can lead to brain damage in animal models. Neuronal cells exposed to ethanol showed an increase in reactive oxygen species (ROS), oxidative damage and mitochondrial impairment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4f76ad8550e028eb9187aec71853f7
https://doi.org/10.1016/j.neuropharm.2020.108100
https://doi.org/10.1016/j.neuropharm.2020.108100
Autor:
Alejandra Aranguiz, Hugo Sepulveda, Roman Thaler, Marcelo Antonelli, Nelson Varela, Ricardo D. Moreno, Andre J. van Wijnen, Mario Galindo, Martin Montecino, Gary S. Stein, Carlos Lizama
Publikováno v:
Journal of Cellular Physiology. 231:1001-1014
Epigenetic mechanisms mediate the acquisition of specialized cellular phenotypes during tissue development, maintenance and repair. When phenotype-committed cells transit through mitosis, chromosomal condensation counteracts epigenetic activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca4862b64308a80750c4147abf22a496
https://doi.org/10.1002/jcp.25188
https://doi.org/10.1002/jcp.25188
Autor:
Francisca Villavicencio-Tejo, Margrethe A. Olesen, Alejandra Aránguiz, Rodrigo A. Quintanilla
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 515 (2022)
Alzheimer’s disease (AD) is characterized by memory and cognitive impairment, accompanied by the accumulation of extracellular deposits of amyloid β-peptide (Aβ) and the presence of neurofibrillary tangles (NFTs) composed of pathological forms of
Externí odkaz:
https://doaj.org/article/04028c56d8da461eae9a937e53b717e3
Publikováno v:
Redox Biology, Vol 18, Iss , Pp 279-294 (2018)
Tau is a key protein for microtubule stability; however, post-translationally modified tau contributes to neurodegenerative diseases by forming tau aggregates in the neurons. Previous reports from our group and others have shown that pathological for
Externí odkaz:
https://doaj.org/article/bf6e8f3c840e4b1b9356370f540c69fe