Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Alejandra, Kun"'
Autor:
Lucia Vázquez Alberdi, Marcela Martínez-Busi, Eloisa Arrarte, Carolina Echeverry, Miguel Calero, Alejandra Kun
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Curcumin is a polyphenol extracted from Curcuma longa’s roots. Low doses of curcumin are related to anti-inflammatory, antioxidant, and neuroprotective effects, while high doses are used for their lethality. This diversity of behaviors all
Externí odkaz:
https://doaj.org/article/bc7e498d18424c2da145b84ba90b76f3
Autor:
Maximiliano Anzibar Fialho, Lucia Vázquez Alberdi, Mariana Martínez, Miguel Calero, Jerome Baranger, Mickael Tanter, Juan Pablo Damián, Carlos Negreira, Nicolás Rubido, Alejandra Kun, Javier Brum
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The hippocampus plays an important role in learning and memory, requiring high-neuronal oxygenation. Understanding the relationship between blood flow and vascular structure—and how it changes with ageing—is physiologically and anatomica
Externí odkaz:
https://doaj.org/article/ee96aa2208c6407d92959aa9f4d70f30
Autor:
Mariana Martínez Barreiro, Lucia Vázquez Alberdi, Lucila De León, Guadalupe Avellanal, Andrea Duarte, Maximiliano Anzibar Fialho, Jérôme Baranger, Miguel Calero, Nicolás Rubido, Mickael Tanter, Carlos Negreira, Javier Brum, Juan Pablo Damián, Alejandra Kun
Publikováno v:
Biology, Vol 12, Iss 10, p 1324 (2023)
The main human hereditary peripheral neuropathy (Charcot-Marie-Tooth, CMT), manifests in progressive sensory and motor deficits. Mutations in the compact myelin protein gene pmp22 cause more than 50% of all CMTs. CMT1E is a subtype of CMT1 myelinopat
Externí odkaz:
https://doaj.org/article/646ddf5f16ca456891999fd89466cc07
Autor:
Maximiliano Anzibar Fialho, Lucia Vázquez Alberdi, Mariana Martínez, Miguel Calero, Jerome Baranger, Mickael Tanter, Juan Pablo Damián, Carlos Negreira, Nicolás Rubido, Alejandra Kun, Javier Brum
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/23ffae8cb0d443ff88f045cb4355d7a4
Autor:
Lucia Vázquez Alberdi, Gonzalo Rosso, Lucía Velóz, Carlos Romeo, Joaquina Farias, María Vittoria Di Tomaso, Miguel Calero, Alejandra Kun
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 515 (2022)
Charcot-Marie-Tooth (CMT) syndrome is the most common progressive human motor and sensory peripheral neuropathy. CMT type 1E is a demyelinating neuropathy affecting Schwann cells due to peripheral-myelin-protein-22 (PMP22) mutations, modelized by Tre
Externí odkaz:
https://doaj.org/article/6c7603d6b3604962a24865e82ca883db
Autor:
María Vittoria Di Tomaso, Lucía Vázquez Alberdi, Daniela Olsson, Saira Cancela, Anabel Fernández, Juan Carlos Rosillo, Ana Laura Reyes Ábalos, Magdalena Álvarez Zabaleta, Miguel Calero, Alejandra Kun
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 456 (2022)
Myelination of the peripheral nervous system requires Schwann cells (SC) differentiation into the myelinating phenotype. The peripheral myelin protein-22 (PMP22) is an integral membrane glycoprotein, expressed in SC. It was initially described as a g
Externí odkaz:
https://doaj.org/article/b9880d27d4854787b6b733f10d73bcad
Autor:
Lucía Canclini, Joaquina Farias, Andrés Di Paolo, José R Sotelo-Silveira, Gustavo Folle, Alejandra Kun, José R Sotelo
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233651 (2020)
Transference of RNAs and ribosomes from Schwann cell-to-axon was demonstrated in normal and regenerating peripheral nerves. Previously, we have shown that RNAs transfer is dependent on F-actin cytoskeleton and Myosin Va. Here, we explored the contrib
Externí odkaz:
https://doaj.org/article/9966cec96f4b47d9b5b29b4071ad53ca
Autor:
Juan Pablo Damián, Lucia Vázquez Alberdi, Lucía Canclini, Gonzalo Rosso, Silvia Olivera Bravo, Mariana Martínez, Natalia Uriarte, Paul Ruiz, Miguel Calero, María Vittoria Di Tomaso, Alejandra Kun
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 601 (2021)
Charcot–Marie–Tooth (CMT) type 1 disease is the most common human hereditary demyelinating neuropathy. Mutations in pmp22 cause about 70% of all CMT1. Trembler-J (TrJ/+) mice are an animal model of CMT1E, having the same spontaneous pmp22 mutatio
Externí odkaz:
https://doaj.org/article/461983feae5e491e80584f460915064d
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 124 (2021)
Aging is associated with an increasing dysfunction of key brain homeostasis mechanisms and represents the main risk factor across most neurodegenerative disorders. However, the degree of dysregulation and the affectation of specific pathways set apar
Externí odkaz:
https://doaj.org/article/c0a1f587ae7b42b0bc86647d2fdbabb3
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Despite aging being by far the greatest risk factor for highly prevalent neurodegenerative disorders, the molecular underpinnings of age-related brain changes are still not well understood, particularly the transition from normal healthy brain aging
Externí odkaz:
https://doaj.org/article/02ace6a4c28b4f25ba35adcb05041a1e