A Single Point Mutation Blocks the Entrance of Ligands to the Cannabinoid CB2 Receptor via the Lipid Bilayer

Autor: Nil Casajuana-Martin, Gemma Navarro, Angel Gonzalez, Claudia Llinas del Torrent, Marc Gómez-Autet, Aleix Quintana García, Rafael Franco, Leonardo Pardo

Publikováno v: Journal of Chemical Information and Modeling. 62:5771-5779

Molecular dynamic (MD) simulations have become a common tool to study the pathway of ligand entry to the orthosteric binding site of G protein-coupled receptors. Here, we have combined MD simulations and site-directed mutagenesis to study the binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309d3d7ed8f319a71e928a1721d46b1c
https://doi.org/10.1021/acs.jcim.2c00865

Interaction of Luminescent Defects in Carbon Nanotubes with Covalently Attached Stable Organic Radicals

Autor: Alexander Högele, Simon Settele, Nicolas F. Zorn, Jana Zaumseil, J. Alejandro de Sousa, Núria Crivillers, Shen Zhao, Abdurrahman Ali El Yumin, Aleix Quintana García, Felix J. Berger

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
ACS Nano

The functionalization of single-walled carbon nanotubes (SWCNTs) with luminescent sp3 defects has greatly improved their performance in applications such as quantum light sources and bioimaging. Here, we report the covalent functionalization of purif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cadc24433280ca0bdc2b649fff9e87
http://hdl.handle.net/10261/239757