Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Aleix Noguera Castells"'
Autor:
Núria Moragas, Patricia Fernandez-Nogueira, Leire Recalde-Percaz, Jamie L. Inman, Anna López-Plana, Helga Bergholtz, Aleix Noguera-Castells, Pedro J. del Burgo, Xieng Chen, Therese Sorlie, Pere Gascón, Paloma Bragado, Mina Bissell, Neus Carbó, Gemma Fuster
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-23 (2024)
Abstract Background A better understanding of ductal carcinoma in situ (DCIS) is urgently needed to identify these preinvasive lesions as distinct clinical entities. Semaphorin 3F (SEMA3F) is a soluble axonal guidance molecule, and its coreceptors Ne
Externí odkaz:
https://doaj.org/article/a7b86ab5f4424b1c832aa95928fa8976
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regulation and other biological processes in humans. On top of that, the DNA methylome undergoes profound changes in cance
Externí odkaz:
https://doaj.org/article/090b776144694434a2a571bfc9b2d78d
Autor:
Carmen Herranz, Francesca Mateo, Alexandra Baiges, Gorka Ruiz de Garibay, Alexandra Junza, Simon R Johnson, Suzanne Miller, Nadia García, Jordi Capellades, Antonio Gómez, August Vidal, Luis Palomero, Roderic Espín, Ana I Extremera, Eline Blommaert, Eva Revilla‐López, Berta Saez, Susana Gómez‐Ollés, Julio Ancochea, Claudia Valenzuela, Tamara Alonso, Piedad Ussetti, Rosalía Laporta, Antoni Xaubet, José A Rodríguez‐Portal, Ana Montes‐Worboys, Carlos Machahua, Jaume Bordas, Javier A Menendez, Josep M Cruzado, Roser Guiteras, Christophe Bontoux, Concettina La Motta, Aleix Noguera‐Castells, Mario Mancino, Enrique Lastra, Raúl Rigo‐Bonnin, Jose C Perales, Francesc Viñals, Alvaro Lahiguera, Xiaohu Zhang, Daniel Cuadras, Coline H M van Moorsel, Joanne J van der Vis, Marian J R Quanjel, Harilaos Filippakis, Razq Hakem, Chiara Gorrini, Marc Ferrer, Aslihan Ugun‐Klusek, Ellen Billett, Elżbieta Radzikowska, Álvaro Casanova, María Molina‐Molina, Antonio Roman, Oscar Yanes, Miquel A Pujana
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 9, Pp 1-21 (2021)
Abstract Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and monitoring can al
Externí odkaz:
https://doaj.org/article/51f572bcdff644bcab3c3cc538fd0d47
Autor:
Arantzazu Zubeldia-Plazaola, Leire Recalde-Percaz, Núria Moragas, Mireia Alcaraz, Xieng Chen, Mario Mancino, Patricia Fernández-Nogueira, Miquel Prats de Puig, Flavia Guzman, Aleix Noguera-Castells, Anna López-Plana, Estel Enreig, Neus Carbó, Vanessa Almendro, Pedro Gascón, Paloma Bragado, Gemma Fuster
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-16 (2018)
Abstract Background The microenvironment and stress factors like glucocorticoids have a strong influence on breast cancer progression but their role in the first stages of breast cancer and, particularly, in myoepithelial cell regulation remains uncl
Externí odkaz:
https://doaj.org/article/09270c8358e54183a6b3aa8944386a95
Autor:
Paloma Bragado, Pere Gascon, Joan Albanell, Ana Lluch, Ana Rovira, Elisabet Ametller, Raul Alonso, Núria Moragas, Leire Recalde-Percaz, Laia Serrano, L. Alex Gaither, Anke Bill, Aleix Noguera-Castells, Federico Rojo, Silvia Menéndez, Estel Enreig, Vanesa Almendro, Patricia Jauregui, Anna López-Plana, Gemma Fuster, Mario Mancino, Patricia Fernández-Nogueira
Fibroblast effect on HER2 activation and HER2-targeted therapies sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09231ac70523ec6b34a3bc7388d36ca9
https://doi.org/10.1158/1078-0432.22473389
https://doi.org/10.1158/1078-0432.22473389
Autor:
Paloma Bragado, Pere Gascon, Joan Albanell, Ana Lluch, Ana Rovira, Elisabet Ametller, Raul Alonso, Núria Moragas, Leire Recalde-Percaz, Laia Serrano, L. Alex Gaither, Anke Bill, Aleix Noguera-Castells, Federico Rojo, Silvia Menéndez, Estel Enreig, Vanesa Almendro, Patricia Jauregui, Anna López-Plana, Gemma Fuster, Mario Mancino, Patricia Fernández-Nogueira
Purpose:Despite the therapeutic success of existing HER2-targeted therapies, tumors invariably relapse. This study aimed at identifying new mechanisms responsible for HER2-targeted therapy resistance.Experimental Design:We have used a platform of HER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75503a5e3c93200695c9cee440396104
https://doi.org/10.1158/1078-0432.c.6528494
https://doi.org/10.1158/1078-0432.c.6528494
Autor:
Paloma Bragado, Pere Gascon, Joan Albanell, Ana Lluch, Ana Rovira, Elisabet Ametller, Raul Alonso, Núria Moragas, Leire Recalde-Percaz, Laia Serrano, L. Alex Gaither, Anke Bill, Aleix Noguera-Castells, Federico Rojo, Silvia Menéndez, Estel Enreig, Vanesa Almendro, Patricia Jauregui, Anna López-Plana, Gemma Fuster, Mario Mancino, Patricia Fernández-Nogueira
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153a4e30a5aa46b033fbfa300e7a966b
https://doi.org/10.1158/1078-0432.22473374.v1
https://doi.org/10.1158/1078-0432.22473374.v1
Autor:
Paloma Bragado, Pere Gascon, Joan Albanell, Ana Lluch, Ana Rovira, Elisabet Ametller, Raul Alonso, Núria Moragas, Leire Recalde-Percaz, Laia Serrano, L. Alex Gaither, Anke Bill, Aleix Noguera-Castells, Federico Rojo, Silvia Menéndez, Estel Enreig, Vanesa Almendro, Patricia Jauregui, Anna López-Plana, Gemma Fuster, Mario Mancino, Patricia Fernández-Nogueira
File describing the supplementary material and methods and the table for the antibodies and drugs used for treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ce7a3aa0167e9564d668793e69fb08
https://doi.org/10.1158/1078-0432.22473371.v1
https://doi.org/10.1158/1078-0432.22473371.v1
Autor:
Leire Recalde-Percaz, Patricia Jauregui, Anna López-Plana, Patricia Fernandéz-Nogueira, Minerva Iniesta-González, Sara Manzano, Raul Alonso, Aleix Noguera-Castells, Nuria Moragas, Cristina Baquero, Maria Rodrigo-Faus, Nerea Palao, Erica Dalla, Francesc Xavier Aviles-Jurado, Isabel Vilaseca, Mercedes Camacho, Xavier Leon-Vintro, Gemma Fuster, Jordi Alcaraz, Julio Aguirre-Ghiso, Pere Gascón, Álvaro Gutierrez-Uzquiza, Almudena Porras, Neus Carbo, Paloma Bragado
Metastasis is the main cause of death from solid tumours and, therefore, identifying the mechanisms that govern metastatic growth poses a major biomedical challenge. We and others have contributed to demonstrate that tumour microenvironment (TME) sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b50ab09281c91f60bb11817aabd1805b
https://doi.org/10.21203/rs.3.rs-1956933/v1
https://doi.org/10.21203/rs.3.rs-1956933/v1
Autor:
Aleix Noguera-Castells, Fina Martínez-Soler, N Núria, L Passoni, G Bourmeau, Leire Pedrosa, Elisabetta Stanzani, Avelina Tortosa, G Seano, Océane Anezo
Publikováno v:
Neuro-Oncology. 23:ii18-ii19
BACKGROUND The plasticity of tumoral cells and the presence of cells displaying stem-like features are two interrelated traits of Glioblastoma (GBM) lesions and both concur in defining its heterogeneity. Particularly, GBM stem-like cells (GSC) can be