Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Aleix Gavaldà-Navarro"'
Autor:
Pere Domingo, Marta Giralt, Aleix Gavaldà-Navarro, Albert Blasco-Roset, Alejandro Delgado-Anglés, José Miguel Gallego-Escuredo, Maria Del Mar Gutiérrez, Maria Gracia Mateo, Rubén Cereijo, Joan Carles Domingo, Francesc Villarroya, Joan Villarroya
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 143-152 (2022)
Lipodystrophy is a major disturbance in people living with HIV-1 (PLWH). Several systemic alterations in PLWH are reminiscent of those that occur in ageing. It is unknown whether the lipodystrophy in PLWH is the consequence of accelerated ageing in a
Externí odkaz:
https://doaj.org/article/61ce931dcec94416a091169e2a981474
Autor:
Moisés Castellá, Albert Blasco-Roset, Marion Peyrou, Aleix Gavaldà-Navarro, Joan Villarroya, Tania Quesada-López, Leyre Lorente-Poch, Juan Sancho, Florian Szymczak, Anthony Piron, Sonia Rodríguez-Fernández, Stefania Carobbio, Albert Goday, Pere Domingo, Antonio Vidal-Puig, Marta Giralt, Décio L. Eizirik, Francesc Villarroya, Rubén Cereijo
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106847- (2023)
Summary: Adipose tissue from pheochromocytoma patients acquires brown fat features, making it a valuable model for studying the mechanisms that control thermogenic adipose plasticity in humans. Transcriptomic analyses revealed a massive downregulatio
Externí odkaz:
https://doaj.org/article/28b4ea636229492aaaac613396fa4a6a
Autor:
Jessica Latorre, Ramon Díaz-Trelles, Ferran Comas, Aleix Gavaldà-Navarro, Edward Milbank, Nathalia Dragano, Samantha Morón-Ros, Rajesh Mukthavaram, Francisco Ortega, Anna Castells-Nobau, Núria Oliveras-Cañellas, Wifredo Ricart, Priya P. Karmali, Kiyoshi Tachikawa, Pad Chivukula, Francesc Villarroya, Miguel López, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 599-613 (2022)
Circulating lipopolysaccharide-binding protein (LBP) is increased in individuals with liver steatosis. We aimed to evaluate the possible impact of liver LBP downregulation using lipid nanoparticle-containing chemically modified LBP small interfering
Externí odkaz:
https://doaj.org/article/2318b693c0cb490ab904a421bf554622
Autor:
Jessica Latorre, Francisco Ortega, Núria Oliveras-Cañellas, Ferran Comas, Aina Lluch, Aleix Gavaldà-Navarro, Samantha Morón-Ros, Wifredo Ricart, Francesc Villarroya, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 870-879 (2022)
Lipopolysaccharide binding protein (Lbp) has been recently identified as a relevant component of innate immunity response associated to adiposity. Here, we aimed to investigate the impact of adipose tissue Lbp on weight gain and white adipose tissue
Externí odkaz:
https://doaj.org/article/f9dbfee1ff5c4a26b586d69304553e65
Autor:
Ferran Comas, Ramon Díaz-Trelles, Aleix Gavaldà-Navarro, Edward Milbank, Nathalia Dragano, Samantha Morón-Ros, Rajesh Mukthavaram, Jessica Latorre, Francisco Ortega, Maria Arnoriaga-Rodriguez, Núria Oliveras-Cañellas, Wifredo Ricart, Priya P. Karmali, Kiyoshi Tachikawa, Pad Chivukula, Francesc Villarroya, Marta Giralt, Miguel López, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 151, Iss , Pp 113156- (2022)
Background and aims: The sexual dimorphism in fat-mass distribution and circulating leptin and insulin levels is well known, influencing the progression of obesity-associated metabolic disease. Here, we aimed to investigate the possible role of lipop
Externí odkaz:
https://doaj.org/article/aa1f1e08da414ca3b75ee9401097de0f
Autor:
Cristina Garcia-Beltran, Joan Villarroya, Cristina Plou, Aleix Gavaldà-Navarro, Paula Casano, Rubén Cereijo, Francis de Zegher, Abel López-Bermejo, Lourdes Ibáñez, Francesc Villarroya
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
ObjectiveBone morphogenetic protein-8B (BMP8B) is an adipokine produced by brown adipose tissue (BAT) contributing to thermoregulation and metabolic homeostasis in rodent models. In humans, BAT activity is particularly relevant in newborns and young
Externí odkaz:
https://doaj.org/article/70791fb172184b85bbcd57ed3c175262
Autor:
Marion Peyrou, Rubén Cereijo, Tania Quesada-López, Laura Campderrós, Aleix Gavaldà-Navarro, Laura Liñares-Pose, Elena Kaschina, Thomas Unger, Miguel López, Marta Giralt, Francesc Villarroya
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Brown adipose tissue, known produce heat by metabolizing fat, is also secretes molecules capable of communicating with other organs. Here the authors show that brown adipose tissue secretes kininogen, a component of heat system regulation, that provi
Externí odkaz:
https://doaj.org/article/150ca23506ff4dd1a06c23947991322f
Autor:
Serena Mirra, Rocío García-Arroyo, Elena B. Domènech, Aleix Gavaldà-Navarro, Carlos Herrera-Úbeda, Clara Oliva, Jordi Garcia-Fernàndez, Rafael Artuch, Francesc Villarroya, Gemma Marfany
Publikováno v:
Neurobiology of Disease, Vol 156, Iss , Pp 105405- (2021)
The retina is a highly active metabolic organ that displays a particular vulnerability to genetic and environmental factors causing stress and homeostatic imbalance. Mitochondria constitute a bioenergetic hub that coordinates stress response and cell
Externí odkaz:
https://doaj.org/article/0690107645da4812a47e1d8b7f822eff
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 2018 (2021)
The precise function of CERKL, a Retinitis Pigmentosa (RP) causative gene, is not yet fully understood. There is evidence that CERKL is involved in the regulation of autophagy, stress granules, and mitochondrial metabolism, and it is considered a gen
Externí odkaz:
https://doaj.org/article/b5a7d3f782e8436cb2f389002b955895
Autor:
Serena Mirra, Aleix Gavaldà-Navarro, Yasmina Manso, Mónica Higuera, Román Serrat, María Teresa Salcedo, Ferran Burgaya, José Maria Balibrea, Eva Santamaría, Iker Uriarte, Carmen Berasain, Matias A. Avila, Beatriz Mínguez, Eduardo Soriano, Francesc Villarroya
Publikováno v:
Cancers, Vol 13, Iss 5, p 1110 (2021)
ARMCX3 is encoded by a member of the Armcx gene family and is known to be involved in nervous system development and function. We found that ARMCX3 is markedly upregulated in mouse liver in response to high lipid availability, and that hepatic ARMCX3
Externí odkaz:
https://doaj.org/article/087185bcc3da43dfaafb3952f09c0c63