Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aled, Finniear"'
Autor:
Kevin Stephens, Florence Huynh, Thomas Wirth, Rudolf Konrad Allemann, Matthew Tailby, Aled Finniear
Publikováno v:
Angewandte Chemie (International Ed. in English)
Process intensification through continuous flow reactions has increased the production rates of fine chemicals and pharmaceuticals. Catalytic reactions are accelerated through an unconventional and unprecedented use of a high‐performance liquid/liq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c8ab39556cb50354951962258f307f
https://doi.org/10.1002/anie.202005183
https://doi.org/10.1002/anie.202005183
Autor:
Kevin Stephens, Thomas Wirth, Florence Huynh, Aled Finniear, Rudolf Konrad Allemann, Matthew Tailby
Publikováno v:
Angewandte Chemie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a937808dfd555cee7c77654d3b05f31f
https://doi.org/10.1002/ange.202005183
https://doi.org/10.1002/ange.202005183
Autor:
Jonathan, Powell, Filipa, Mota, David, Steadman, Christelle, Soudy, Jeremy T, Miyauchi, Stuart, Crosby, Ashley, Jarvis, Tifelle, Reisinger, Natalie, Winfield, Graham, Evans, Aled, Finniear, Tamas, Yelland, Yi-Tai, Chou, A W Edith, Chan, Andrew, O'Leary, Lili, Cheng, Dan, Liu, Constantina, Fotinou, Carla, Milagre, John F, Martin, Haiyan, Jia, Paul, Frankel, Snezana, Djordjevic, Stella E, Tsirka, Ian C, Zachary, David L, Selwood
Publikováno v:
Journal of Medicinal Chemistry
We report the design, synthesis, and biological evaluation of some potent small-molecule neuropilin-1 (NRP1) antagonists. NRP1 is implicated in the immune response to tumors, particularly in Treg cell fragility, required for PD1 checkpoint blockade.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e56ed2e21a55c2767ecc12a8b43909b2
https://pubmed.ncbi.nlm.nih.gov/29648813
https://pubmed.ncbi.nlm.nih.gov/29648813