Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alecia G. Knight"'
Autor:
Annadora J. Bruce-Keller, Sunita Gupta, Alecia G. Knight, Tina L. Beckett, Jessica M. McMullen, Paulina R. Davis, M. Paul Murphy, Linda J. Van Eldik, Daret St Clair, Jeffrey N. Keller
Publikováno v:
Neurobiology of Disease, Vol 44, Iss 3, Pp 317-326 (2011)
Cognitive impairment in Alzheimer's disease (AD) is strongly associated with both extensive deposition of amyloid β peptides and oxidative stress, but the exact role of these indices in the development of dementia is not clear. This study was design
Externí odkaz:
https://doaj.org/article/3e615ba232eb4f6f9ad4d8e7823830a8
Autor:
Daret K. St. Clair, Sunita Gupta, M. Paul Murphy, Alecia G. Knight, Paulina R. Davis, Annadora J. Bruce-Keller, Tina L. Beckett, Jeffrey N. Keller, Linda J. Van Eldik, Jessica M. McMullen
Publikováno v:
Neurobiology of Disease, Vol 44, Iss 3, Pp 317-326 (2011)
Cognitive impairment in Alzheimer’s disease (AD) is strongly associated with both extensive deposition of amyloid β peptides and oxidative stress, but the exact role of these indices in the development of dementia is not clear. This study was desi
Autor:
Sunita Gupta, Taryn E. Parrino, Harry LeVine, Jeffrey N. Keller, Philip J. Ebenezer, Adam M. Weidner, Annadora J. Bruce-Keller, Alecia G. Knight, William R. Markesbery
Publikováno v:
Antioxidants & Redox Signaling. 12:1371-1382
This study was undertaken to investigate the profile of NADPH oxidase (NOX) in the clinical progression of Alzheimer's disease (AD). Specifically, NOX activity and expression of the regulatory subunit p47phox and the catalytic subunit gp91phox was ev
Autor:
Alecia G. Knight, Boriss Y. Losso, Annadora J. Bruce-Keller, Jeffrey N. Keller, Donald K. Ingram, Sunita Gupta
Publikováno v:
Antiviral research. 95(1)
HIV-associated neurocognitive disorders (HAND) remain prevalent even with widespread use of combination antiretroviral therapy (ART), suggesting a potential role for co-morbidities in neurologic decline. Indeed, it is well established that ART drugs,
Publikováno v:
Journal of Neurochemistry.
This study describes the effects of long-chain fatty acids on inflammatory signaling in cultured astrocytes. Data show that the saturated fatty acid palmitic acid, as well as lauric acid and stearic acid, trigger the release of TNFα and IL-6 from as
Autor:
Donald K. Ingram, Alecia G. Knight, Jeffrey N. Keller, Michelle Domingue, Carmen Ruiz, Romina María Uranga, Sunita Gupta, Paul J. Pistell, Indu Kheterpal, Annadora J. Bruce-Keller
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
It is well established that HIV antiretroviral drugs, particularly protease inhibitors, frequently elicit a metabolic syndrome that may include hyperlipidemia, lipodystrophy, and insulin resistance. Metabolic dysfunction in non-HIV-infected subjects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8022c53ef46ea042e82d2198c49df667
https://www.sciencedirect.com/science/article/pii/S0166354210007679
https://www.sciencedirect.com/science/article/pii/S0166354210007679
Autor:
Alecia G. Knight, Jeffrey N. Keller, Shruti Gupta, Pamela E. Knapp, Sunita Gupta, Annadora J. Bruce-Keller, Kurt F. Hauser
Publikováno v:
Neuroscience letters. 485(3)
Excitotoxicity and/or microglial reactivity might underlie neurologic dysfunction in HIV patients. The HIV regulatory protein Tat is both neurotoxic and pro-inflammatory, suggesting that Tat might participate in the pathogenesis of HIV-associated neu
Autor:
Christopher D. Morrison, Sunita Gupta, Christy L. White, Donald K. Ingram, Jeffrey N. Keller, Alecia G. Knight, Paul J. Pistell, Annadora J. Bruce-Keller
This study describes how age and high fat diet affect the profile of NADPH oxidase (NOX). Specifically, NOX activity and subunit expression were evaluated in the frontal cerebral cortex of 7-, 16-, and 24-month old mice following a 4-month exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbaac220bd2353a116a703cb0937f7f
https://europepmc.org/articles/PMC2875353/
https://europepmc.org/articles/PMC2875353/
Autor:
Paul J. Pistell, Donald K. Ingram, Alecia G. Knight, Annadora J. Bruce-Keller, Christopher D. Morrison, Jeffrey N. Keller, Sunita Gupta
C57Bl/6 mice were administered a high fat, Western diet (WD, 41% fat) or a very high fat lard diet (HFL, 60% fat), and evaluated for cognitive ability using the Stone T-maze and for biochemical markers of brain inflammation. WD consumption resulted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d0440bb3a986fe58b8636d33488ec6
https://europepmc.org/articles/PMC2823983/
https://europepmc.org/articles/PMC2823983/
Autor:
Annadora J. Bruce-Keller, Sunita Gupta, Taryn E. Parrino, Alecia G. Knight, Philip J. Ebenezer, Adam M. Weidner, Harry LeVine, Jeffrey N. Keller, William R. Markesbery
Publikováno v:
Antioxidants & Redox Signaling; Jun2010, Vol. 12 Issue 12, p1371-1382, 12p