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pro vyhledávání: '"Alec Saitman"'
Autor:
Alec Saitman
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 28, Iss , Pp 56-59 (2023)
Externí odkaz:
https://doaj.org/article/9e62890322cd4d39a456754beb3c99d9
Publikováno v:
The journal of applied laboratory medicine. 6(5)
Background Tacrolimus has a low therapeutic index requiring strict control of whole blood concentrations. Although random access immunoassay platforms exist that rapidly provide quantitative values for tacrolimus, LC–MS/MS may provide more accurate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e80569b340ee616018fb30d9354c9e
https://pubmed.ncbi.nlm.nih.gov/34136903
https://pubmed.ncbi.nlm.nih.gov/34136903
Autor:
Scott Marsal, Alec Saitman, Walter J. Urba, Justin Jin, David Ball, Amy Compton-Phillips, Veronica Luzzi, Rom Leidner, Carlo Bifulco, Angi Frary, Nancy Frisco, Brian D. Piening, Mark A Schmidt, Kevin Olson, Jeffrey A Young, David Leidner, Roshanthi Weerasinghe, Kendall Sawa, Julie Cramer
Frontline healthcare workers (HCW) are a high-risk population for SARS-CoV-2 infection. Here we present results from a large serosurveillance study of 10,019 asymptomatic HCW conducted during April-May 2020, in eight hospital medical centers across t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ef13a2d3c0a62fd34425f13fd81ad0
Publikováno v:
Clinical Chemistry. 64:1291-1293
A 31-year-old pregnant woman at 25-week gestation was admitted for preterm premature rupture of membranes and subsequently delivered preterm at 29 weeks. The patient insisted that she was unaware of the pregnancy and, thus, received no prenatal care.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626304c8af33755551237e431bdeff91
https://doi.org/10.1373/clinchem.2017.283507
https://doi.org/10.1373/clinchem.2017.283507
Autor:
Alec Saitman
This chapter serves as a general overview of separation and mass spectrometry (MS) methods most commonly employed in clinical and forensic laboratories performing drugs of abuse testing. The information is presented in three basic components: molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aca1c7bb898ec76194b3d518366a3b2
https://doi.org/10.1016/b978-0-12-815607-0.00013-7
https://doi.org/10.1016/b978-0-12-815607-0.00013-7
Autor:
Sohail Ahmed, Brian D. Ahrens, D. Adam Algren, Olof Beck, Roger L. Bertholf, Joshua A. Bornhorst, Larry Broussard, Anthony W. Butch, Carl Cooley, Steven W. Cotten, Amitava Dasgupta, Pradip Datta, Lauren Dvorscak, Mahmoud A. ElSohly, Albert D. Fraser, Shanlin Fu, Uttam Garg, Shahbaz W. Gul, Waseem Gul, Justin Holler, George F. Jackson, John F. Jemionek, Kamisha L. Johnson-Davis, Hannah Kastenbaum, Steven C. Kazmierczak, Matthew D. Krasowski, Tai C. Kwong, Loralie J. Langman, Barry Levine, Jennifer Lowry, Veronica Luzzi, Ernest D. Lykissa, Anu S. Maharjan, Hans H. Maurer, Michael M. Mbughuni, Gwendolyn McMillin, Laura Mercolini, Markus R. Meyer, Marilyn R. Past, Buddha Dev Paul, Lori Proe, Michele Protti, Gary M. Reisfield, Lilian H.J. Richter, Alexia Rylski, Alec Saitman, Eric T. Shimomura, Christine L.H. Snozek, Niclas Nikolai Stephanson, Michelle Wood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3fd538a9a1d0c044dd8f04487248b3
https://doi.org/10.1016/b978-0-12-815607-0.00040-x
https://doi.org/10.1016/b978-0-12-815607-0.00040-x
Publikováno v:
Journal of Bone and Mineral Research. 31:1841-1844
The CYP24A1 gene encodes a mitochondrial 24-hydroxylase that inactivates 1,25(OH)2 D. Loss-of-function mutations in CYP24A1 cause hypercalcemia, nephrolithiasis and nephrocalcinosis. We describe a woman with CYP24A1 deficiency and recurrent gestation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3295b3799ac04145b28fc349943ae2
https://doi.org/10.1002/jbmr.2859
https://doi.org/10.1002/jbmr.2859
Publikováno v:
Journal of analytical toxicology. 43(1)
Adulteration of samples submitted for toxicological analyses can present unique challenges to non-forensic clinical laboratories. With the number of overdose-related deaths expected to surpass 60,000 in 2018, it is incumbent on all members of the hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc794f5fdbbb7834e26eb9bbe0ec609b
https://pubmed.ncbi.nlm.nih.gov/30192938
https://pubmed.ncbi.nlm.nih.gov/30192938
Publikováno v:
Tetrahedron Letters. 54:1612-1615
An efficient strategy for the construction of C13-oxidized cembrenolides is reported. Central to this strategy is the installation of the C13 hydroxyl group prior to cembrane macrocyclization (via formation of the C1–C2 bond), allowing access to bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e2347438a1d8b04c7702ac530cf698
https://doi.org/10.1016/j.tetlet.2013.01.085
https://doi.org/10.1016/j.tetlet.2013.01.085
Publikováno v:
Therapeutic drug monitoring, vol 38, iss 3
Saitman, A; Metushi, IG; Mason, DS; & Fitzgerald, RL. (2016). Evaluation of the waters masstrak LC-MS/MS assay for tacrolimus and a comparison to the abbott architect immunoassay. Therapeutic Drug Monitoring, 38(3), 300-304. doi: 10.1097/FTD.0000000000000252. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2gd1r24z
Saitman, A; Metushi, IG; Mason, DS; & Fitzgerald, RL. (2016). Evaluation of the waters masstrak LC-MS/MS assay for tacrolimus and a comparison to the abbott architect immunoassay. Therapeutic Drug Monitoring, 38(3), 300-304. doi: 10.1097/FTD.0000000000000252. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2gd1r24z
Author(s): Saitman, Alec; Metushi, Imir G; Mason, Donald S; Fitzgerald, Robert L | Abstract: BackgroundTacrolimus (Prograf, Advagraf, and FK-506) is the most commonly prescribed calcineurin inhibitor after kidney and liver transplantation. The use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fdc73c5a8347b054c454b2cee79c7c
https://escholarship.org/uc/item/2gd1r24z
https://escholarship.org/uc/item/2gd1r24z