Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alec Redwood"'
Autor:
Rebecca Pavlos, Elizabeth J. McKinnon, David A. Ostrov, Bjoern Peters, Soren Buus, David Koelle, Abha Chopra, Ryan Schutte, Craig Rive, Alec Redwood, Susana Restrepo, Austin Bracey, Thomas Kaever, Paisley Myers, Ellen Speers, Stacy A. Malaker, Jeffrey Shabanowitz, Yuan Jing, Silvana Gaudieri, Donald F. Hunt, Mary Carrington, David W. Haas, Simon Mallal, Elizabeth J. Phillips
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Genes of the human leukocyte antigen (HLA) system encode cell-surface proteins involved in regulation of immune responses, and the way drugs interact with the HLA peptide binding groove is important in the immunopathogenesis of T-cell mediat
Externí odkaz:
https://doaj.org/article/713379e67e8e4c309dc4c182e4231712
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004268 (2014)
TNF-related apoptosis inducing ligand (TRAIL) death receptors (DR) regulate apoptosis and inflammation, but their role in antiviral defense is poorly understood. Cytomegaloviruses (CMV) encode many immune-modulatory genes that shape host immunity, an
Externí odkaz:
https://doaj.org/article/df99f2d44b9a4acb96d781f896d5ad79
Autor:
Franck Housseau, Drew Pardoll, Alec Redwood, Camie Chan, Yanxing Yu, Chunfa Jie, Vedran Radojcic, Jang-June Park, Hongni Fan, Maria Pletneva
Supplementary Tables 1-2 from IFN-Producing Killer Dendritic Cells Are Antigen-Presenting Cells Endowed with T-Cell Cross-Priming Capacity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff616e0e2f7f6067366f6c016b7e0c1
https://doi.org/10.1158/0008-5472.22378335
https://doi.org/10.1158/0008-5472.22378335
Autor:
Franck Housseau, Drew Pardoll, Alec Redwood, Camie Chan, Yanxing Yu, Chunfa Jie, Vedran Radojcic, Jang-June Park, Hongni Fan, Maria Pletneva
Supplementary Methods from IFN-Producing Killer Dendritic Cells Are Antigen-Presenting Cells Endowed with T-Cell Cross-Priming Capacity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed52fcb9072cf018b655deb151ab609
https://doi.org/10.1158/0008-5472.22378338
https://doi.org/10.1158/0008-5472.22378338
Autor:
Franck Housseau, Drew Pardoll, Alec Redwood, Camie Chan, Yanxing Yu, Chunfa Jie, Vedran Radojcic, Jang-June Park, Hongni Fan, Maria Pletneva
Supplementary Figures 1-8 from IFN-Producing Killer Dendritic Cells Are Antigen-Presenting Cells Endowed with T-Cell Cross-Priming Capacity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9483523339bb12975d3a4e5b04b62d80
https://doi.org/10.1158/0008-5472.22378341
https://doi.org/10.1158/0008-5472.22378341
Publikováno v:
Oncoimmunology. 11(1)
The process of tumorigenesis leaves a series of indelible genetic changes in tumor cells, that when expressed, have the potential to be tumor-specific immune targets. Neoantigen vaccines that capitalize on this potential immunogenicity have shown eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110ab4cfcbda63738c438c6fe6a09e92
https://pubmed.ncbi.nlm.nih.gov/35186441
https://pubmed.ncbi.nlm.nih.gov/35186441
Autor:
Linda Ye, Ian Dick, Peter Chiang, Tina Firth, Jenette Creaney, Bruce WS Robinson, Alec Redwood
Publikováno v:
Journal of Clinical Oncology. 40:e21111-e21111
e21111 Background: Following repeated tumor antigen stimulation, T cells lose functional capacity and become exhausted. T cell exhaustion is a progressive change in phenotype. Early in the pathway, stem-like exhausted T cells (Texstem) retain prolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab26964357e7082399b1946e4b3308d0
https://doi.org/10.1200/jco.2022.40.16_suppl.e21111
https://doi.org/10.1200/jco.2022.40.16_suppl.e21111
Autor:
Shamin Li, Yannick Simoni, Summer Zhuang, Shaokang Ma, Jonathan Chee, Alec Redwood, Bruce Robinson, Evan Newell
Publikováno v:
The Journal of Immunology. 204:165.13-165.13
The most promising cancer immunotherapies to date target immune checkpoint receptors, such as PD-1 and CTLA-4. However, T cell checkpoint blockade has no inherent tumor specificity and shows uneven response, with up to 70–80% of patients resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f12d4f688ecaaad15a87aaa0e348aaf8
https://doi.org/10.4049/jimmunol.204.supp.165.13
https://doi.org/10.4049/jimmunol.204.supp.165.13
Autor:
Thomas Kaever, Imir G Metushi, Rebecca Pavlos, John Sidney, David A Ostrov, Soren Buus, Alec Redwood, Alessandro Sette, Donald F Hunt, Elizabeth J Phillips, Bjoern Peters
Publikováno v:
The Journal of Immunology. 198:55.42-55.42
Immune mediated adverse drug reactions (IM-ADRs) pose a significant risk to human health, and have been shown to be linked to specific human leukocyte antigen (HLA) alleles. Hypersensitivity syndrome induced by abacavir, the strongest such genetic as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45c1d281660dc417dbfb472024777f0f
https://doi.org/10.4049/jimmunol.198.supp.55.42
https://doi.org/10.4049/jimmunol.198.supp.55.42
Autor:
Katherine Chanel Konvinse, Katie White, Rebecca Pavlos, Alec Redwood, Jason Trubiano, Elizabeth Ergen, Simon Alexander Mallal, Elizabeth J Phillips
Publikováno v:
The Journal of Immunology. 196:191.24-191.24
Severe immune-mediated adverse drug reactions (IM-ADRs) significantly impact patient outcome and inflict substantial cost on healthcare and drug development. Many of these T-cell mediated reactions are now known to be class I and/or class II HLA rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37399812384de8ddc97b70577052094
https://doi.org/10.4049/jimmunol.196.supp.191.24
https://doi.org/10.4049/jimmunol.196.supp.191.24