Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alec R, Andrews"'
Autor:
Marion Goutard, Pierre Tawa, Yanis Berkane, Alec R. Andrews, Casie A. Pendexter, Reinier J. de Vries, Victor Pozzo, Golda Romano, Hyshem H. Lancia, Irina Filz von Reiterdank, Nicolas Bertheuil, Ivy A. Rosales, Ira Doressa Anne L. How, Mark A. Randolph, Alexandre G. Lellouch, Curtis L. Cetrulo, Korkut Uygun
Publikováno v:
Transplant International, Vol 37 (2024)
The current gold standard for preserving vascularized composite allografts (VCA) is 4°C static cold storage (SCS), albeit muscle vulnerability to ischemia can be described as early as after 2 h of SCS. Alternatively, machine perfusion (MP) is growin
Externí odkaz:
https://doaj.org/article/a62d3e5b3d914106bb7bafd0c309c4e6
Autor:
Philipp Tratnig-Frankl, Alec R. Andrews, Yanis Berkane, Claire Guinier, Marion Goutard, Elise Lupon, Hyshem H. Lancia, Michael L. Morrison, Mark B. Roth, Mark A. Randolph, Curtis L. Cetrulo, Alexandre G. Lellouch
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 531 (2024)
Vascularized composite allografts (VCA) face ischemic challenges due to their limited availability. Reperfusion following ischemia triggers oxidative stress and immune reactions, and scavenger molecules could mitigate ischemia–reperfusion injuries
Externí odkaz:
https://doaj.org/article/2607fd12640742a6a3cf10c2cf94d8f3
Autor:
Elise Lupon, Aylin Acun, Corentin B. Taveau, Ruben Oganesyan, Hyshem H. Lancia, Alec R. Andrews, Mark A. Randolph, Curtis L. Cetrulo, Alexandre G. Lellouch, Basak E. Uygun
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 321 (2024)
Reconstructive techniques to repair severe tissue defects include the use of autologous fasciocutaneous flaps, which may be limited due to donor site availability or lead to complications such as donor site morbidity. A number of synthetic or natural
Externí odkaz:
https://doaj.org/article/d282c18ab62a472288ac6ea48f53448b
Autor:
Alexandre G. Lellouch, Alec R. Andrews, Gaelle Saviane, Zhi Yang Ng, Ilse M. Schol, Marion Goutard, Amon-Ra Gama, Ivy A. Rosales, Robert B. Colvin, Laurent A. Lantieri, Mark A. Randolph, Gilles Benichou, Curtis L. Cetrulo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundVascularized composite allografts (VCAs) allow reconstruction of devastating injuries and amputations, yet require lifelong immunosuppression that is associated with significant morbidity. Induction of immune tolerance of VCAs would permit
Externí odkaz:
https://doaj.org/article/9edd525b71754b0d840e1d03aaddef28
Autor:
Alec R. Andrews, Zhaohui Wang, Robert A. Wilkinson, Jay A. Fishman, David H. Sachs, Nalu Navarro-Alvarez, Christene A. Huang
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Establishment of transplantable tumors in clinically relevant large animals allows translational studies of novel cancer therapeutics. Methods Here we describe the establishment, characterization, and serial transplantation of a n
Externí odkaz:
https://doaj.org/article/42ace78e79df4bb19cec97369d6049d5
Autor:
ELISE LUPON, M.D, Aylin Acun, PhD, Marion Goutard, M..D, Alexandre G. Lellouch, M.D, MSc, Ruben Oganesyan, M.D, Alec R. Andrews, BS, Laurent Lantieri, M.D, Mark A. Randolph, PhD, Curtis L. Cetrulo, Jr., M.D, FACS, FAAP, Basak Uygun, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 9, Iss 7S, Pp 29-30 (2021)
Purpose: The decellularization of Vascularized Composite Allotransplantation (VCA) represents a first step in circumventing the need for immunosuppression by depleting donor cells from VCAs. Here we present a model of decellularization of VCAs in rat
Externí odkaz:
https://doaj.org/article/18caddaf4eed4d0483ace789e011d583
Autor:
Alec R. Andrews, Ana D. Fernandes, Seth E. Brownmiller, Yousif Hanna, Mark C. Fisher, Christene A. Huang
Publikováno v:
Contemporary Clinical Trials Communications, Vol 17, Iss , Pp - (2020)
Objective: This pilot clinical trial examined the efficacy of blocking extracellular Galectin-3 (Gal-3) with modified citrus pectin (MCP), in patients suffering from knee osteoarthritis (OA). Methods: 50 patients were randomized in a 1:1 ratio to rec
Externí odkaz:
https://doaj.org/article/cf8dc3a1d87c4944804f39068a1e2054
Autor:
Alexandre G. Lellouch, MD, Corentin B. Taveau, MD, Alec R. Andrews, BS, Joseph Molde, BS, Zhi Y. Ng, MD, Philipp Tratnig-Frankl, MD, Mark A. Randolph, MSc, Joachim Kohn, Curtis L. Cetrulo, Jr., MD, FACS
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4S, Pp 33-34 (2020)
Externí odkaz:
https://doaj.org/article/db09b5c49a5f40eb86e453d77942071d
Autor:
Zachariah DeFilipp, Nalu Navarro-Alvarez, Shuli Li, Alec R. Andrews, Ariel Johnson, Yi-Bin Chen, Vincent T. Ho, Jerome Ritz, Thomas R. Spitzer, Christene A. Huang
Publikováno v:
Clinical Hematology International, Vol 1, Iss 4 (2019)
Galectin-3 is a beta-galactoside-binding lectin with an established association to inflammatory and fibrotic conditions. We investigated galectin-3 levels in 68 recipients of allogeneic hematopoietic cell transplantation (HCT) to look for association
Externí odkaz:
https://doaj.org/article/9f5036f957754af48cd575ee99d16d39
Autor:
Pierre Tawa, Marion Goutard, Alec R. Andrews, Reinier J. de Vries, Ivy A. Rosales, Heidi Yeh, Basak Uygun, Mark A. Randolph, Alexandre G. Lellouch, Korkut Uygun, Curtis L. Cetrulo
Publikováno v:
Journal of surgical research, 283, 1145-1153. Academic Press Inc.
Introduction: Multiple perfusion systems have been investigated on vascularized composite allografts, with various temperatures and different preservation solutions, most using continuous flow (CF). However, physiological flow is pulsatile and provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6388636a4901f5b36e6e2ce36bef42
https://pure.amc.nl/en/publications/continuous-versus-pulsatile-flow-in-24h-vascularized-composite-allograft-machine-perfusion-in-swine(fa4d8574-c03f-4ec8-9de9-3f23ca690248).html
https://pure.amc.nl/en/publications/continuous-versus-pulsatile-flow-in-24h-vascularized-composite-allograft-machine-perfusion-in-swine(fa4d8574-c03f-4ec8-9de9-3f23ca690248).html
