Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alec N. Woosley"'
Autor:
Toros Dincman, Breege V. Howley, Simon Grelet, Alec N. Woosley, Shaun K. Olsen, Bidyut K. Mohanty, Annamarie C. Dalton, Philip H. Howe, George S. Hussey, Sean Bloos
Publikováno v:
Oncogene
FAM3C/Interleukin-like EMT Inducer (ILEI) is an oncogenic member of the FAM3 cytokine family and serves essential roles in both epithelial-mesenchymal transition (EMT) and breast cancer metastasis. ILEI expression levels are regulated through a non-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecbb54c681e247b0c54ba4025ef167c
http://europepmc.org/articles/PMC6525020
http://europepmc.org/articles/PMC6525020
Autor:
Sarah M. Sterling, Richard M. Walsh, Hanqin Peng, Bing Chen, Jun Zhang, Alec N. Woosley, Tianshu Xiao, Jianming Lu, Wei Yang, Sophia Rits-Volloch, Haisun Zhu, Piotr Sliz, Yongfei Cai
Publikováno v:
Science (New York, N.Y.). 372(6541)
How an early variant got ahead Throughout the COVID-19 pandemic, epidemiologists have monitored the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with particular focus on the spike protein. An early variant with an asparti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16df8ffbce9abcf545ca6ea50e52aa27
https://pubmed.ncbi.nlm.nih.gov/34133867
https://pubmed.ncbi.nlm.nih.gov/34133867
Publikováno v:
Protein Science. 24:946-955
The giant proteins titin and obscurin are important for sarcomeric organization, stretch response, and sarcomerogenesis in myofibrils. The extreme C-terminus of titin (the M10 domain) binds to the N-terminus of obscurin (the Ig1 domain) in the M-band
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86109189b6bdf9d618ee856eaa2fe530
https://doi.org/10.1002/pro.2670
https://doi.org/10.1002/pro.2670
Autor:
Zongyang Lv, Alec N. Woosley, Kimberly A. Rickman, Philip H. Howe, Shanmugam Panneer Selvam, K.M. Williams, Besim Ogretmen, Lingmin Yuan, Agata Smogorzewska, Shaun K. Olsen
Ubiquitin (Ub) E1 initiates the Ub conjugation cascade by activating and transferring Ub to tens of different E2s. How Ub E1 cooperates with E2s that differ substantially in their predicted E1-interacting residues is unknown. Here, we report the stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cecfcd8a103faa667e971532bd40d5
https://europepmc.org/articles/PMC5319395/
https://europepmc.org/articles/PMC5319395/
Publikováno v:
Cell Cycle. 15:3319-3320
Epithelial to mesenchymal transition (EMT) is postulated to be required for the initiation of tumor cell metastasis.1 Disabled-2 (Dab2) has been shown to play an essential role during TGFβ-mediated...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4c3eb60a48322215ebfcc0deb0b430
https://doi.org/10.1080/15384101.2016.1222747
https://doi.org/10.1080/15384101.2016.1222747
Autor:
Alec N. Woosley, Nathan T. Wright
Publikováno v:
Biophysical Journal. 104(2)
Obscurin (700-800 kD) is a giant modular protein involved in many aspects of muscle cell organization and maintenance. Disregulation of obscurin leads to supermolecular deformities of the sarcomeric cytoskeleton, and mutations of obscurin and its tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d97667681ed2c9ee15cf1b98f49503