Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alec L.W. Dick"'
Autor:
Juan Pablo Lopez, Malte D. Lücken, Elena Brivio, Stoyo Karamihalev, Aron Kos, Carlo De Donno, Asaf Benjamin, Huanqing Yang, Alec L.W. Dick, Rainer Stoffel, Cornelia Flachskamm, Andrea Ressle, Simone Roeh, Rosa-Eva Huettl, Andrea Parl, Carola Eggert, Bozidar Novak, Yu Yan, Karin Yeoh, Maria Holzapfel, Barbara Hauger, Daniela Harbich, Bianca Schmid, Rossella Di Giaimo, Christoph W. Turck, Mathias V. Schmidt, Jan M. Deussing, Matthias Eder, Julien Dine, Fabian J. Theis, Alon Chen
A single sub-anesthetic dose of ketamine produces a rapid and sustained antidepressant response, yet the molecular mechanisms responsible for this remain unclear. Here, we identified cell-type-specific transcriptional signatures associated with a sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65cd49786fe8c5bfdb8836783f07ac71
http://hdl.handle.net/11588/891105
http://hdl.handle.net/11588/891105
Autor:
Alon Chen, Alec L.W. Dick
Exposure to stressful life events is considered a major risk factor predisposing individuals to stress-related psychiatric disorders such as major depressive disorder and posttraumatic stress disorder. Mounting evidence indicates that epigenetic mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4719492b400987fe6df85cf3f896eb
https://doi.org/10.1016/b978-0-12-813156-5.00004-2
https://doi.org/10.1016/b978-0-12-813156-5.00004-2
Autor:
Qiongyi Zhao, Danay Baker-Andresen, Timothy W. Bredy, Simone Roeh, Rose Crossin, Jhodie R. Duncan, Alec L.W. Dick, Victoria Marshall, Andrew J Lawrence, Janette Edson, Xiang Li
Publikováno v:
Addiction biologyREFERENCES. 26(3)
Inhalants containing the volatile solvent toluene are misused to induce euphoria or intoxication. Inhalant abuse is most common during adolescence and can result in cognitive impairments during an important maturational period. Despite evidence sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1592649610b620655c6808c6d858cef9
https://pubmed.ncbi.nlm.nih.gov/32638524
https://pubmed.ncbi.nlm.nih.gov/32638524
Autor:
Alec L.W. Dick, Alon Chen
Publikováno v:
Neurobiology of Stress
Neurobiology of Stress, Vol 15, Iss, Pp 100352-(2021)
Neurobiology of Stress, Vol 15, Iss, Pp 100352-(2021)
Over the past decade, critical, non-redundant roles of the ten-eleven translocation (TET) family of dioxygenase enzymes have been identified in the brain during developmental and postnatal stages. Specifically, TET-mediated active demethylation, invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ed0c94f1189c2934578705badf33d2
https://doi.org/10.1016/j.ynstr.2021.100352
https://doi.org/10.1016/j.ynstr.2021.100352
Publikováno v:
Frontiers in Psychiatry
Frontiers in Psychiatry, Vol 10 (2019)
Frontiers in Psychiatry, Vol 10 (2019)
Adenosine-to-inosine (A-to-I) RNA editing is a co-/posttranscriptional modification of double-stranded RNA, catalyzed by the adenosine deaminase acting on RNA (ADAR) family of enzymes, which results in recognition of inosine as guanosine by translati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e168f8b747b50c7762ea264fe399e3f
http://europepmc.org/articles/PMC6512728
http://europepmc.org/articles/PMC6512728
Autor:
Nadine Provencal, Alec L.W. Dick
Dynamic adaptation to stressful life events requires the co-ordinated action of the central stress response, which is mediated by the hypothalamic-pituitary-adrenal (HPA) axis, to restore and maintain homeostasis. Excessive exposure to stress or trau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc9a5c5a7fc094182a7d46d7bc81ac1b
https://doi.org/10.1016/bs.pmbts.2018.04.006
https://doi.org/10.1016/bs.pmbts.2018.04.006
Autor:
Ashleigh Qama, Zane B. Andrews, Amanda Simpson, Andrew J Lawrence, Jhodie R. Duncan, Alec L.W. Dick
Publikováno v:
British Journal of Pharmacology. 172:5174-5187
Background and Purpose Abuse of toluene-containing inhalants is an increasing public health problem, especially among adolescents. Abuse during adolescence is associated with emaciation, while industrial exposure leads to altered glycaemic control su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98e2ef6428b8788e1edf051866b3d047
https://doi.org/10.1111/bph.13284
https://doi.org/10.1111/bph.13284
Autor:
Emma Giles, Andrew J Lawrence, Alec L.W. Dick, Tine Pooters, Jhodie R. Duncan, Sarah Jane Gibbs, Ashleigh Qama
Publikováno v:
Brain Research. 1624:239-252
The purposeful inhalation of volatile solvents, such as toluene, to induce self-intoxication is prevalent, particularly within adolescent populations. Chronic misuse results in cognitive and neurobiological impairments, as well as an increased risk f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32507b81a1b469c2889d50b477e1ed63
https://doi.org/10.1016/j.brainres.2015.07.037
https://doi.org/10.1016/j.brainres.2015.07.037
Publikováno v:
Alcohol. 48:561-569
Voluntary inhalation of organic solvents, such as toluene, is particularly prevalent in adolescent populations and is considered to be a contributing factor to substance use and dependence later in life. While inhalants are often the initial "drug" e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4ccc1bcc14063e3a2e8407fc2b0e86
https://doi.org/10.1016/j.alcohol.2014.08.001
https://doi.org/10.1016/j.alcohol.2014.08.001
Publikováno v:
Psychopharmacology. 231(8)
Inhalant abuse is prevalent in adolescent populations, with chronic use resulting in neurobiological and cognitive abnormalities in adulthood. However, the nature and persistence of cognitive dysfunction, particularly following adolescent inhalant ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8876a7ec3eb186dc54587bd753e8decf
https://pubmed.ncbi.nlm.nih.gov/24322667
https://pubmed.ncbi.nlm.nih.gov/24322667