Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alec Jamieson"'
Suppressed activity of the rostral anterior cingulate cortex as a biomarker for depression remission
Publikováno v:
Psychological Medicine. 53:2448-2455
BackgroundSuppression of the rostral anterior cingulate cortex (rACC) has shown promise as a prognostic biomarker for depression. We aimed to use machine learning to characterise its ability to predict depression remission.MethodsData were obtained f
Publikováno v:
Biological Psychiatry. 93:S73
Autor:
Trevor Steward, Po-Han Kung, Christopher Davey, Bradford Moffat, Rebecca Glarin, Alec Jamieson, Kim Felmingham, Ben Harrison
Publikováno v:
Biological Psychiatry. 91:S226-S227
Publikováno v:
Journal of Affective Disorders. 250:410-418
Background Depression's relationship with cerebral abnormalities and cognitive decline is temporally dynamic. Despite clear clinical utility, understanding depression's effect on cerebral structures, cognitive impairment and the interaction between t
Autor:
Anand S. Dutta, Amanda Rees, Alec Jamieson, Duncan Haworth, Rod S. Kittlety, Lorraine A. Hassall, Paul Gellert, James J. Gormley, Christopher F. Reilly, Peter J. Alcock, Christopher F. Hayward, Linda J. Wood, Mandy L. Crowther, Julie M. Moores
Publikováno v:
Journal of Peptide Science. 6:321-341
Potent monomeric and dimeric cyclic peptide very late antigen-4 (VLA-4) inhibitors have been designed based on a tetrapeptide (Ile-Leu-Asp-Val) sequence present in a 25-amino acid peptide (CS-1) reported in the literature. The peptides, synthesized b
Autor:
Paul Gellert, Peter J. Alcock, Duncan Haworth, Anand S. Dutta, Tracy Halterman, Roger Ferguson, Linda J. Wood, Julie M. Moores, Lorraine A. Hassall, Christopher F. Hayward, James J. Gormley, Christopher F. Reilly, Matthew M Coath, Jackie Moors, Amanda Rees, Rod S. Kittlety, Alec Jamieson
Publikováno v:
Journal of Peptide Science. 6:398-412
Additional structure–activity relationship studies on potent cyclic peptide inhibitors of very late antigen-4 (VLA-4) are reported. The new N- to C-terminal cyclic hexa-, hepta- and octapeptide inhibitors like cyclo(MeIle/MePhe-Leu-Asp-Val-X) (X=2
Autor:
Peter J. Alcock, Amanda Rees, Anand S. Dutta, Alec Jamieson, Christopher F. Reilly, Duncan Haworth, Huw B Jones, Linda J. Wood, James J. Gormley
Publikováno v:
British Journal of Pharmacology. 126:1751-1760
1. Small, N- to C-terminal cyclized peptides containing the leucyl-aspartyl-valine (LDV) motif from fibronectin connecting segment-1 (CS-1) have been investigated for their effects on the adhesion of human T-lymphoblastic leukaemia cells (MOLT-4) to
Publikováno v:
Thrombosis and Haemostasis. 77:1168-1173
SummaryMonocytes, macrophages and foam cells are central to atherogenesis. We have examined the potential ability of monocytes, macrophages and foam cells to affect the stability of deposited fibrin, characteristic of the atherosclerotic plaque, by t
Publikováno v:
Thrombosis and Haemostasis. 74:1521-1527
SummaryFibrin deposition is a characteristic feature of the atherosclerotic plaque. The balance of fibrinolytic activity is modulated by plasminogen activators (PAs) and plasminogen activator inhibitors (PAIs). We examined expression of components of
Publikováno v:
Blood. 86(9)
Fibrin deposition is characteristic of inflammatory diseases. The monocytes is central to the inflammatory response and can affect fibrinolysis by expression of urokinase (u-PA) and plasminogen activator inhibitor types 1 and 2 (PAI-1 and PAI-2, resp