Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alec Freyn"'
Autor:
Dario Garcia-Dominguez, Carole Henry, LingZhi Ma, Hardik Jani, Nicholas J. Amato, Taylor Manning, Alec Freyn, Heather Davis, Chiaowen Joyce Hsiao, Mengying Li, Hillary Koch, Sayda Elbashir, Anthony DiPiazza, Andrea Carfi, Darin Edwards, Kapil Bahl
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
For a vaccine to achieve durable immunity and optimal efficacy, many require a multi-dose primary vaccination schedule that acts to first “prime” naive immune systems and then “boost” initial immune responses by repeated immunizations (ie, pr
Externí odkaz:
https://doaj.org/article/7ceed16ea2d0483aa3c331e1bda0099f
Autor:
Jenna Guthmiller, Linda Yu-Ling Lan, Lei Li, Carole Henry, Christopher Stamper, Henry Utset, Alec Freyn, Julianna Han, Olivia Stovicek, Jiaolong Wang, Nai-Ying Zheng, Min Huang, Haley Dugan, Micah Tepora, Xueyong Zhu, Yao-Qing Chen, Anna-Karin Palm, Dustin Shaw, Madhumanthi Loganathan, Benjamin Francis, Mia McNair, Philip Mead, Ian Wilson, Adolfo Garcia-Sastre, Raffael Nachbagauer, Peter Palese, Andrew Ward, Lynda Coughlan, Florian Krammer, Patrick Wilson
In a phase I clinical trial, the chimeric hemagglutinin (cHA) immunogen induced antibody responses against the conserved HA stalk domain. However, the landscape of the B cell specificities and subsets induced by this vaccine remain undetermined. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de79b74f725fd6cd48343f3ef38289c0
https://doi.org/10.21203/rs.3.rs-2600472/v1
https://doi.org/10.21203/rs.3.rs-2600472/v1
Autor:
Jenna Guthmiller, Lei Li, Linda Yu-Ling Lan, Carole Henry, Christopher Stamper, Alec Freyn, Henry Utset, Julianna Han, Peter Palese, Lynda Coughlan, Andrew Ward, Florian Krammer, Patrick C Wilson
Publikováno v:
The Journal of Immunology. 208:126.32-126.32
Seasonal influenza virus vaccines provide modest protection against endemic viruses but lack effectiveness against pandemic-threat viruses. Therefore, new immunogens and vaccine platforms that induce antibodies against broadly protective epitopes are