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Autor:
Rebekka Grundler, Anke Spoo, Alec Bullock, Laurent Brault, Sabine Woetzel, Sabine Ehret, Tobias Dechow, Stefan Knapp, Martjin Nawijn, Andrea Biondi, Juerg Schwaller, Justus Duyster, G. Berridge, Christelle Gasser, Christine Dierks
Publikováno v:
BLOOD. 112(11)
Previous work has shown that FLT3-ITD mediated leukemogenesis is associated with increased expression of PIM1 and PIM2 serine/threonine kinases. Here we show that retroviral expression of FLT3-ITD could not compensate impaired clonogenic in vitro gro