Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aleš Premzl"'
Autor:
Vesna Hodnik, Aleš Premzl, Bojana Mirković, Zala Jevnikar, Bojan Doljak, Janko Kos, Gregor Anderluh
Publikováno v:
FEBS Journal. 276:4739-4751
Cathepsin B (EC 3.4.22.1) is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity. The former is associated with the degradation of the extracellular matrix proteins, which is a process required for tumour cell invasion and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b517effab3c7cdc8aa9dca2ec18418ea
https://doi.org/10.1111/j.1742-4658.2009.07171.x
https://doi.org/10.1111/j.1742-4658.2009.07171.x
Publikováno v:
Experimental Cell Research. 312:2515-2527
Cathepsin X is a lysosomal carboxypeptidase with a potential role in processes of inflammation and immune response. The integrin-binding motifs RGD and ECD, present in the pro- and in mature forms of cathepsin X, respectively, suggest that this enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c305146cbaae031750e7525d4376fd
https://doi.org/10.1016/j.yexcr.2006.04.019
https://doi.org/10.1016/j.yexcr.2006.04.019
Publikováno v:
Journal of Cellular Biochemistry. 97:1230-1240
The lysosomal cysteine protease cathepsin B is implicated in degradation of extracellular matrix (ECM), a crucial step in a variety of physiological and pathological processes, including tumor dissemination and angiogenesis. In this study, we analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a5473a1d7d3127dbd7bf0d8b8c3e76
https://doi.org/10.1002/jcb.20720
https://doi.org/10.1002/jcb.20720
Autor:
Tomaz Langerholc, Rastko Golouh, Vito Turk, Bernd Werle, Boris Turk, Matjaz Jeras, Urska Repnik, Valentina Zavasnik Bergant, Aleš Premzl, Janko Kos, Andreja Sekirnik
Publikováno v:
Experimental Cell Research. 306:103-113
Cathepsin X, a recently discovered lysosomal cysteine protease, shares common structural features and activity properties with cysteine protease cathepsin B. Based on its widespread mRNA distribution in primary tumors and tumor cell lines, a redundan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5d79a0f7d943b988917047e904c50e
https://doi.org/10.1016/j.yexcr.2004.12.006
https://doi.org/10.1016/j.yexcr.2004.12.006
Publikováno v:
Experimental Cell Research. 283:206-214
Lysosomal cysteine proteinase cathepsin B is implicated in remodeling the extracellular matrix, a crucial step in the process of tumor cell invasion. In this study the contributions of intracellular and extracellular cathepsin B activities in the inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c31e2213a272e0f3bbf346629e21d62
https://doi.org/10.1016/s0014-4827(02)00055-1
https://doi.org/10.1016/s0014-4827(02)00055-1
Autor:
Katarina, Fidler, Simona, Jevševar, Tatjana, Milunović, Spela, Skrajnar, Aleš, Premzl, Menči, Kunstelj, Irena, Zore, Barbara, Podobnik, Mateja, Kusterle, Simon, Caserman, Maja, Kenig, Vanja, Smilović, Ladka, Gaberc-Porekar
Publikováno v:
Acta chimica Slovenica. 58(1)
G-CSF successfully prevents chemotherapy-induced neutropenia. Two second-generation drugs with improved therapeutic properties are already available and the development of new forms is still ongoing. For an efficient receptor dimerization two G-CSF m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5f6c0e10d77a3770abcd3f6f6bb3b63
https://pubmed.ncbi.nlm.nih.gov/24061936
https://pubmed.ncbi.nlm.nih.gov/24061936
Ammodytoxin C (AtxC) is a toxic secreted phospholipase A2 (sPLA2) from the venom of Vipera ammodytes snake. To evaluate its potential to kill cancer cells, the toxin was cross-linked to the monoclonal antibody against cathepsin B which endocytoses up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48751465c10c91d4fbbc3f610d1f1138
https://www.bib.irb.hr/313890
https://www.bib.irb.hr/313890
Publikováno v:
Experimental cell research. 301(2)
Cystatins are able to inhibit the tumor-associated activity of intracellular cysteine proteases cathepsins B and L and have been suggested as potential anticancer drugs. We have incorporated chicken cystatin, a model protein inhibitor of cysteine pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088f3850ed0d01041c68f4e8914068be
https://pubmed.ncbi.nlm.nih.gov/15530858
https://pubmed.ncbi.nlm.nih.gov/15530858
Publikováno v:
Biological chemistry. 383(11)
The lysosomal cysteine protease cathepsin B is one of several proteases that have been linked to tumour progression. Its increased expression and secretion in tumour cells may facilitate the degradation of extracellular matrix proteins, leading to tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ffe9da3108ca5aa8f6774231095c21
https://pubmed.ncbi.nlm.nih.gov/12530548
https://pubmed.ncbi.nlm.nih.gov/12530548