Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Aldose reductase (ALR2)"'
Autor:
Khalid Alshaghdali, Munazzah Tasleem, Raja Rezgui, Talal Alharazi, Tolgahan Acar, Raed Fahad Aljerwan, Ahmed Altayyar, Samra Siddiqui, Mohd Saeed, Dharmendra Kumar Yadav, Amir Saeed
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35255- (2024)
Diabetes mellitus (DM) is a prominent contributor to morbidity and mortality in developed nations, primarily attributable to vascular complications such as atherothrombosis occurring in the coronary arteries. Aldose reductase (ALR2), the main enzyme
Externí odkaz:
https://doaj.org/article/67dd6a63112e4097ab81b13c1f038d44
Autor:
Kundur, Sunitha, Shyam, Perugu ⁎
Publikováno v:
In Journal of Molecular Structure 15 September 2024 1312 Part 1
Autor:
Alshaghdali, Khalid a, 1, Tasleem, Munazzah b, 1, Rezgui, Raja a, Alharazi, Talal a, i, Acar, Tolgahan c, Aljerwan, Raed Fahad d, Altayyar, Ahmed d, Siddiqui, Samra e, Saeed, Mohd f, j, ⁎, Yadav, Dharmendra Kumar h, ⁎⁎, Saeed, Amir a, g
Publikováno v:
In Heliyon 15 August 2024 10(15)
Autor:
Hlaváč, Matúš a, ⁎, Kováčiková, Lucia b, Šoltésová Prnová, Marta b, Addová, Gabriela a, Hanquet, Gilles c, Štefek, Milan b, Boháč, Andrej a, d
Publikováno v:
In Bioorganic & Medicinal Chemistry 1 January 2021 29
Autor:
Shehzad, Muhammad Tariq a, Hameed, Abdul b, al-Rashida, Mariya b, Imran, Aqeel c, Uroos, Maliha d, Asari, Asnuzilawati e, Mohamad, Habsah f, Islam, Muhammad a, Iftikhar, Shafia g, Shafiq, Zahid a, Iqbal, Jamshed c
Publikováno v:
In Bioorganic Chemistry November 2019 92
Autor:
Nencetti, Susanna a, ⁎, La Motta, Concettina a, Rossello, Armando a, Sartini, Stefania a, Nuti, Elisa a, Ciccone, Lidia b, Orlandini, Elisabetta a, c
Publikováno v:
In Bioorganic & Medicinal Chemistry 15 June 2017 25(12):3068-3076
Akademický článek
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Autor:
Vyas, Bhawna a, Singh, Manjinder b, Kaur, Maninder b, Bahia, Malkeet Singh b, Jaggi, Amteshwar Singh c, Silakari, Om b, Singh, Baldev a, ⁎
Publikováno v:
In Journal of Molecular Graphics and Modelling June 2015 59:59-71
Autor:
Gilles Hanquet, Gabriela Addová, Matúš Hlaváč, Marta Soltesova Prnova, Milan Stefek, Lucia Kovacikova, Andrej Boháč
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2020
Bioorganic and Medicinal Chemistry, Elsevier, 2021, 29, pp.115885. ⟨10.1016/j.bmc.2020.115885⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2020
Bioorganic and Medicinal Chemistry, Elsevier, 2021, 29, pp.115885. ⟨10.1016/j.bmc.2020.115885⟩
International audience; Recently we have developed novel oxotriazinoindole inhibitors (OTIs) of aldose reductase (ALR2), characterized by high efficacy and selectivity. Herein we describe novel OTI derivatives design of which is based on implementati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9864da0d8d175b47891ee35ec8f429
https://hal.archives-ouvertes.fr/hal-03070904/document
https://hal.archives-ouvertes.fr/hal-03070904/document
Autor:
Lidia Ciccone, Armando Rossello, Stefania Sartini, Elisabetta Orlandini, Elisa Nuti, Susanna Nencetti, Concettina La Motta
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:3068-3076
Aldose reductase (ALR2), a NADPH-dependent reductase, is the first and rate-limiting enzyme of the polyol pathway of glucose metabolism and is implicated in the pathogenesis of secondary diabetic complications. In the last decades, this enzyme has be