Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Aldona Karaczyn"'
Autor:
M. Elena Martinez, Aldona Karaczyn, Zhaofei Wu, Christian A. Bennett, Kassey L. Matoin, Heather M. Daigle, Arturo Hernandez
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Intergenerational and transgenerational epigenetic effects resulting from conditions in previous generations can contribute to environmental adaptation as well as disease susceptibility. Previous studies in rodent and human models have shown that abn
Externí odkaz:
https://doaj.org/article/eb62e49c6b9a4101a43275389842ccf3
Publikováno v:
Endocrinology. 160:2929-2945
Premature overexposure to thyroid hormone causes profound effects on testis growth, spermatogenesis, and male fertility. We used genetic mouse models of type 3 deiodinase (DIO3) deficiency to determine the genetic programs affected by premature thyro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cfea3aacfdd1604adb29b0c6dd70e3
https://doi.org/10.1210/en.2019-00259
https://doi.org/10.1210/en.2019-00259
Publikováno v:
Journal of the Endocrine Society
The influence of thyroid hormone (TH) on male reproduction is not well understood. Male mice lacking the type 3 deiodinase (DIO3), which inactivates TH, exhibit deficits in testis growth, reproductive hormone levels, spermatogenesis and fertility (Ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55e142b4b2d87b251f73661a0c8c8ae
http://europepmc.org/articles/PMC6555064
http://europepmc.org/articles/PMC6555064
Autor:
J. Patrizia Stohn, Zhaofei Wu, Arturo Hernandez, Christine W. Duarte, M. Elena Martinez, Victoria E. DeMambro, Aldona Karaczyn
Publikováno v:
Molecular Psychiatry. 25:915-915
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fcbb56dd5d9f26666bc9dc099b658de
https://doi.org/10.1038/s41380-020-0732-6
https://doi.org/10.1038/s41380-020-0732-6
Autor:
Aldona Karaczyn, Victoria E. DeMambro, J. Patrizia Stohn, M. Elena Martinez, Christine W. Duarte, Zhaofei Wu, Arturo Hernandez
Publikováno v:
Molecular psychiatry
Genetic factors do not fully account for the relatively high heritability of neurodevelopmental conditions, suggesting that non-genetic heritable factors contribute to their etiology. To evaluate the potential contribution of aberrant thyroid hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24b99575f18d2a7a2539c3dd551d1fa
http://europepmc.org/articles/PMC6482106
http://europepmc.org/articles/PMC6482106
Autor:
Kailin Xu, Aldona Karaczyn, Calvin P.H. Vary, Rose McGlauflin, Don M. Wojchowski, Amanda J. Favreau-Lessard, Pan Li, Pradeep Sathyanarayana, Edward Jachimowicz
Podocalyxin (Podxl) is a CD34 orthologue and cell surface sialomucin reported to have roles in renal podocyte diaphragm slit development; vascular cell integrity; and the progression of blood, breast, and prostate cancers. Roles for Podxl during nonm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3679f3987bf072d7aadfe3edac524f
https://europepmc.org/articles/PMC5560106/
https://europepmc.org/articles/PMC5560106/
Publikováno v:
Blood. 134:3704-3704
The preservation of hematopoietic stem cell pool in bone marrow (BM) is crucial for sustained hematopoiesis in adults. Studies assessing adult hematopoietic stem cells functionality had been shown that for example loss of quiescence impairs hematopoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::752b9cd3b6c095d572e5530929fd7824
https://doi.org/10.1182/blood-2019-126283
https://doi.org/10.1182/blood-2019-126283
Autor:
Aldona Karaczyn, Arturo Hernandez, Walburga Croteau, W. William Donnelly, P. Robin Peeters, J. Patrizia Stohn, Valerie Anne Galton, M. Elena Martinez, Donald L. St. Germain, Douglas Forrest
Publikováno v:
Endocrinology, 157(3), 1276-1288. Endocrine Society
Timely and appropriate levels of thyroid hormone (TH) signaling are necessary to ensure normal developmental outcomes in many tissues. Studies using pharmacological models of altered TH status have revealed an influence of these hormones on testis de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9e64ee030d6608d097d5477f5fbcd6
https://europepmc.org/articles/PMC4769364/
https://europepmc.org/articles/PMC4769364/
Publikováno v:
Advances in Bioscience and Biotechnology. :1206-1213
Non-canonical bone morphogenic protein (BMP) pathway signaling plays a critical role during embryonic neurogenesis, inducing apoptosis and eliminating an excess of neural progenitor cells, in preparation for the population of the neural stem cell nic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d424ea20148f4d11dcb0e93d7e8ce7b1
https://doi.org/10.4236/abb.2012.38147
https://doi.org/10.4236/abb.2012.38147
Publikováno v:
Blood. 132:1283-1283
Several recent studies have showed that dysregulation of microRNA (miRNA) expression in hematopoietic stem cells (HSC) can affect self-renewal of HSCs, and indicated a role for miRNAs in development of acute myeloid leukemia (AML). We and others have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe74e0c97ef7a31ad9b319494765c85f
https://doi.org/10.1182/blood-2018-99-116381
https://doi.org/10.1182/blood-2018-99-116381