Zobrazeno 1 - 10
of 545
pro vyhledávání: '"Aldo Roda"'
Autor:
Valentina Marassi, Stefano Giordani, Anna Placci, Angela Punzo, Cristiana Caliceti, Andrea Zattoni, Pierluigi Reschiglian, Barbara Roda, Aldo Roda
Publikováno v:
Sensors, Vol 23, Iss 23, p 9432 (2023)
The early-stage diagnosis of cancer is a crucial clinical need. The inadequacies of surgery tissue biopsy have prompted a transition to a less invasive profiling of molecular biomarkers from biofluids, known as liquid biopsy. Exosomes are phospholipi
Externí odkaz:
https://doaj.org/article/a558a1ce31ff48108d9e5768f45830c3
Autor:
Rossana Comito, Emanuele Porru, Nicolò Interino, Matteo Conti, Rossella Terragni, Roberto Gotti, Marco Candela, Patrizia Simoni, Aldo Roda, Jessica Fiori
Publikováno v:
Metabolites, Vol 13, Iss 9, p 980 (2023)
Bile acids (BAs), endogenous acidic steroids synthetized from cholesterol in the liver, play a key role in the gut–liver axis physiopathology, including in hepatotoxicity, intestinal inflammatory processes, and cholesterol homeostasis. Faecal Oxo-B
Externí odkaz:
https://doaj.org/article/a6f3a79864954ad3bda28dac229ef1d0
Autor:
Emanuele Porru, Daniel Scicchitano, Nicolò Interino, Teresa Tavella, Marco Candela, Aldo Roda, Jessica Fiori
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract There is a growing interest in the named “acidic sterolbiome” and in the genetic potential of the gut microbiome (GM) to modify bile acid (BA) structure. Indeed, the qualitative composition of BAs in feces correlates with the bowel micro
Externí odkaz:
https://doaj.org/article/204177e42d78489c8267f81e6af77b92
Autor:
Emanuele Porru, Enrico Giorgi, Silvia Turroni, Riccardo Helg, Michele Silani, Marco Candela, Jessica Fiori, Aldo Roda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Small organic molecules, lipids, proteins, and DNA fragments can remain stable over centuries. Powerful and sensitive chemical analysis can therefore be used to characterize ancient remains for classical archaeological studies. This bio-ecol
Externí odkaz:
https://doaj.org/article/53dea459de8349f6bbf137db19c4aff1
Autor:
Marica Cariello, Roberta Zerlotin, Emanuela Pasculli, Elena Piccinin, Claudia Peres, Emanuele Porru, Aldo Roda, Raffaella Maria Gadaleta, Antonio Moschetta
Publikováno v:
Cancers, Vol 14, Iss 13, p 3081 (2022)
The Farnesoid X Receptor (FXR) is the master regulator of Bile Acids (BA) homeostasis orchestrating their synthesis, transport and metabolism. Disruption of BA regulation has been linked to gut-liver axis diseases such as colorectal cancer (CRC). In
Externí odkaz:
https://doaj.org/article/f506277605474a699db46b87f5165ecd
Autor:
Bruce R. Branchini, Danielle M. Fontaine, Dawn Kohrt, Brian P. Huta, Allison R. Racela, Benjamin R. Fort, Tara L. Southworth, Aldo Roda
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2451 (2022)
Luciferases catalyze light-emitting reactions that produce a rainbow of colors from their substrates (luciferins), molecular oxygen, and often additional cofactors. These bioluminescence (BL) systems have afforded an incredible variety of basic resea
Externí odkaz:
https://doaj.org/article/eacff8a83fa3445bb4f3a5a297cfe3fe
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100137- (2021)
Externí odkaz:
https://doaj.org/article/544ba47d2260494281c52b2c79c0a2a7
Autor:
Chiara Donadei, Andrea Angeletti, Maria Cappuccilli, Massimiliano Conti, Diletta Conte, Fulvia Zappulo, Alessio De Giovanni, Deborah Malvi, Rita Aldini, Aldo Roda, Gaetano La Manna
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 3, p 636 (2022)
Background: Acute kidney injury (AKI) is common in advanced liver cirrhosis, a consequence of reduced kidney perfusion due to splanchnic arterial vasodilation and intrarenal vasoconstriction. It clinically manifests as hepatorenal syndrome type 1, ty
Externí odkaz:
https://doaj.org/article/c53cc372e5ec4059a799a480006dae62
Autor:
Raffaella Maria Gadaleta, Oihane Garcia-Irigoyen, Marica Cariello, Natasha Scialpi, Claudia Peres, Stefania Vetrano, Gionatha Fiorino, Silvio Danese, Brian Ko, Jian Luo, Emanuele Porru, Aldo Roda, Carlo Sabbá, Antonio Moschetta
Publikováno v:
EBioMedicine, Vol 57, Iss , Pp 102873- (2020)
Externí odkaz:
https://doaj.org/article/45a648545eec440587640640c1f66604
Autor:
Natalia K. Lajczak‐McGinley, Emanule Porru, Ciara M. Fallon, Jessica Smyth, Caitriona Curley, Paul A. McCarron, Murtaza M. Tambuwala, Aldo Roda, Stephen J. Keely
Publikováno v:
Physiological Reports, Vol 8, Iss 12, Pp n/a-n/a (2020)
Abstract Increased epithelial permeability is a key feature of IBD pathogenesis and it has been proposed that agents which promote barrier function may be of therapeutic benefit. We have previously reported the secondary bile acid, ursodeoxycholic ac
Externí odkaz:
https://doaj.org/article/2b0487f316c14fe68a346b6bcc45c740