Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Aldo Moggio"'
Autor:
Ulrike Meyer-Lindemann, Carina Mauersberger, Anna-Christina Schmidt, Aldo Moggio, Julia Hinterdobler, Xinghai Li, David Khangholi, Jan Hettwer, Christian Gräßer, Alexander Dutsch, Heribert Schunkert, Thorsten Kessler, Hendrik B. Sager
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundInflammation strongly contributes to atherosclerosis initiation and progression. Consequently, recent clinical trials pharmacologically targeted vascular inflammation to decrease the incidence of atherosclerosis-related complications. Colch
Externí odkaz:
https://doaj.org/article/28df352c26204badaafd3cad9c9270cf
Autor:
Irene Franco, Hafdis T. Helgadottir, Aldo Moggio, Malin Larsson, Peter Vrtačnik, Anna Johansson, Nina Norgren, Pär Lundin, David Mas-Ponte, Johan Nordström, Torbjörn Lundgren, Peter Stenvinkel, Lars Wennberg, Fran Supek, Maria Eriksson
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-22 (2019)
Abstract Background The lifelong accumulation of somatic mutations underlies age-related phenotypes and cancer. Mutagenic forces are thought to shape the genome of aging cells in a tissue-specific way. Whole genome analyses of somatic mutation patter
Externí odkaz:
https://doaj.org/article/a0b5804ee3f14ea3ae1dd947efe10ff8
Autor:
Nicholas H Adamstein, Wolfgang Koenig, Peter Libby, Christian Weber, Paul M. Ridker, Marcus-André Deutsch, Oliver Soehnlein, Carina Mauersberger, Hendrik B. Sager, Quinte Braster, Avril A. B. Robertson, Jan Hettwer, Benedikt Miritsch, Mark E. Cooper, Heribert Schunkert, Markus Krane, Xinghai Li, Aldo Moggio, Julia Hinterdobler, Hermann Gram, Olaf Groß, Thorsten Kessler
Publikováno v:
Cardiovascular Research, 118(13):337, 2778-2791. Oxford University Press
AIMS: Targeting vascular inflammation represents a novel therapeutic approach to reduce complications of atherosclerosis. Neutralizing the pro-inflammatory cytokine interleukin-1β (IL-1β) using canakinumab, a monoclonal antibody, reduces the incide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b40381ee58a84da0a5dd30ae3c8b8d7
https://doi.org/10.1093/cvr/cvab337
https://doi.org/10.1093/cvr/cvab337
Autor:
M. Amin Sharifi, Michael Wierer, Tan An Dang, Jelena Milic, Aldo Moggio, Nadja Sachs, Moritz von Scheidt, Julia Hinterdobler, Philipp Müller, Julia Werner, Barbara Stiller, Zouhair Aherrahrou, Jeanette Erdmann, Andrea Zaliani, Mira Graettinger, Jeanette Reinshagen, Sheraz Gul, Philip Gribbon, Lars Maegdefessel, Jürgen Bernhagen, Hendrik B. Sager, Matthias Mann, Heribert Schunkert, Thorsten Kessler
BackgroundTheADAMTS7locus was genome-wide significantly associated with coronary artery disease (CAD). Lack of the extracellular matrix (ECM) protease ADAMTS-7 was shown to reduce atherosclerotic plaque formation.ObjectiveTo identify molecular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54baac038141183d1a9b8af34ae88cb5
https://doi.org/10.1101/2023.03.06.531428
https://doi.org/10.1101/2023.03.06.531428
Publikováno v:
International journal of molecular sciences. 23(24)
Myocardial infarction (MI), a major contributor to worldwide morbidity and mortality, is caused by a lack of blood flow to the heart. Affected heart tissue becomes ischemic due to deficiency of blood perfusion and oxygen delivery. In case sufficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93bf9cb1e0535bc4096260afdd86ac72
https://pubmed.ncbi.nlm.nih.gov/36555456
https://pubmed.ncbi.nlm.nih.gov/36555456
Autor:
M. Amin Sharifi, Michael Wierer, Jelena Milic, Aldo Moggio, Philipp Mueller, Julia Werner, Hendrik Sager, Juergen Bernhagen, Matthias Mann, Heribert Schunkert, Thorsten Kessler
Publikováno v:
Circulation Research. 131
Background: The gene encoding the extracellular matrix (ECM) protease ADAMTS-7 was associated with coronary artery disease (CAD) in genome-wide association studies. ADAMTS-7 is expressed at all stages in human plaques and mice lacking Adamts-7 displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ca6971d83c8132920b596cf4759875
https://doi.org/10.1161/res.131.suppl_1.p1110
https://doi.org/10.1161/res.131.suppl_1.p1110
Autor:
Francesca Del Gaudio, Liqun He, Riikka Pietilä, Michael Vanlandewijck, Lars Muhl, Giuseppe Mocci, Katrine Dahl Bjørnholm, Jianping Liu, Jantine van Voorden, Monica Torres, Aldo Moggio, Salli Antilla, Jon Storm-Mathisen, Linda Hildegard Bergersen, Per Nilsson, Emil Hansson, Kari Alitalo, Urban Lendahl, Johanna Andrae, Christer Betsholtz
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ef5ee1d07870342ac03a7fa1db307e
https://doi.org/10.2139/ssrn.4240422
https://doi.org/10.2139/ssrn.4240422
Publikováno v:
International Journal of Molecular Sciences. 24:3394
Physical exercise represents an effective preventive and therapeutic strategy beneficially modifying the course of multiple diseases. The protective mechanisms of exercise are manifold; primarily, they are elicited by alterations in metabolic and inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bfb377b109201f4ef4fa11d09e8d1b
https://doi.org/10.3390/ijms24043394
https://doi.org/10.3390/ijms24043394
Autor:
Lars Wennberg, Fran Supek, Nina Norgren, Maria Eriksson, Johan Nordström, Hafdis T. Helgadottir, Malin Larsson, Torbjörn Lundgren, Peter Vrtacnik, Aldo Moggio, Peter Stenvinkel, David Mas-Ponte, Irene Franco, Pär Lundin, Anna C. V. Johansson
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-22 (2019)
Genome Biology
Genome Biology
Background The lifelong accumulation of somatic mutations underlies age-related phenotypes and cancer. Mutagenic forces are thought to shape the genome of aging cells in a tissue-specific way. Whole genome analyses of somatic mutation patterns, based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd91d78ef5a6fa12df7c0db38e1e005
https://doaj.org/article/a0b5804ee3f14ea3ae1dd947efe10ff8
https://doaj.org/article/a0b5804ee3f14ea3ae1dd947efe10ff8
Autor:
Jason S. L. Yu, Alleyn T. Plowright, Cindy Lim, Lauren Drowley, Giorgia Palano, Kosuke Yusa, Mohammad Bohlooly-Y, Qing-Dong Wang, Aldo Moggio, Emil M. Hansson, Barry Rosen
Publikováno v:
Stem Cells (Dayton, Ohio)
Direct in vivo reprogramming of cardiac fibroblasts into myocytes is an attractive therapeutic intervention in resolving myogenic deterioration. Current transgene-dependent approaches can restore cardiac function, but dependence on retroviral deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846ae5cba7eb9495358bf1929ecb2051
http://hdl.handle.net/2433/245904
http://hdl.handle.net/2433/245904