Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Aldo Dekker"'
Autor:
Haozhou Li, Pan Liu, Hu Dong, Aldo Dekker, Michiel M. Harmsen, Huichen Guo, Xiangxi Wang, Shiqi Sun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Unlike most other picornaviruses, foot-and-mouth disease (FMD) intact virions (146S) dissociate easily into small pentameric subunits (12S). This causes a dramatically decreased immunogenicity by a mechanism that remains elusive. Here, we pr
Externí odkaz:
https://doaj.org/article/e550e8eba349473b80436111dddd8b18
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2023)
Vaccination with intact (146S) foot-and-mouth disease virus (FMDV) particles is used to control FMD. However, 146S particles easily dissociate into stable pentameric 12S particles which are less immunogenic. We earlier isolated several single-domain
Externí odkaz:
https://doaj.org/article/a0b5326e590f4289a2b5bc7c86079fc4
Autor:
Simon Gubbins, David J. Paton, Aldo Dekker, Anna B. Ludi, Ginette Wilsden, Clare F. J. Browning, Michael Eschbaumer, Jamie Barnabei, Hernando Duque, Lisa L. Pauszek, Donald P. King
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Serology is widely used to predict whether vaccinated individuals and populations will be protected against infectious diseases, including foot-and-mouth disease (FMD), which affects cloven-hoofed animals. Neutralising antibody titres to FMD challeng
Externí odkaz:
https://doaj.org/article/83cbb1ba582a4ce9945540f472480807
Autor:
Aldo Dekker, Herman J. W. van Roermund, Thomas J. Hagenaars, Phaedra L. Eblé, Mart C. M. de Jong
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Quantitative understanding of transmission with and without control measures is important for the control of infectious diseases because it helps to determine which of these measures (or combinations thereof) will be effective to reduce transmission.
Externí odkaz:
https://doaj.org/article/3a860aaf49f14a408249ccfc994b2889
Autor:
Claire Colenutt, Emma Brown, Noel Nelson, David J. Paton, Phaedra Eblé, Aldo Dekker, José L. Gonzales, Simon Gubbins
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Indirect transmission via a contaminated environment can occur for a number of pathogens, even those typically thought of as being directly transmitted, such as influenza virus, norovirus, bovine tuberculosis, or foot-and-mouth disease virus
Externí odkaz:
https://doaj.org/article/c9f62282cffd4db7b8675ea0e9245260
Autor:
Nagendrakumar Balasubramanian Singanallur, Phaedra Lydia Eblé, Anna Barbara Ludi, Bob Statham, Abdelghani Bin-Tarif, Donald P. King, Aldo Dekker, Wilna Vosloo
Publikováno v:
Viruses, Vol 14, Iss 1, p 97 (2022)
The recent emergence and circulation of the A/ASIA/G-VII (A/G-VII) lineage of foot-and-mouth disease virus (FMDV) in the Middle East has resulted in the development of homologous vaccines to ensure susceptible animals are sufficiently protected again
Externí odkaz:
https://doaj.org/article/36d9229bf53c42e58e1c8f0846527a3f
Autor:
Nagendrakumar Balasubramanian Singanallur, Aldo Dekker, Phaedra Lydia Eblé, Froukje van Hemert-Kluitenberg, Klaas Weerdmeester, Jacquelyn J Horsington, Wilna Vosloo
Publikováno v:
Vaccines, Vol 9, Iss 10, p 1110 (2021)
Vaccination is one of the best approaches to control and eradicate foot-and-mouth disease (FMD). To achieve this goal, vaccines with inactivated FMD virus antigen in suitable adjuvants are being used in addition to other control measures. However, on
Externí odkaz:
https://doaj.org/article/c799d1a5e669483db658ce03a7a68d67
Publikováno v:
Vaccines, Vol 9, Iss 6, p 620 (2021)
Foot-and-mouth disease (FMD) vaccine efficacy is mainly determined by the content of intact virions (146S) and empty capsids (75S). Both particles may dissociate into 12S subunits upon vaccine manufacturing, formulation, and storage, reducing vaccine
Externí odkaz:
https://doaj.org/article/5b6d952efc5646b29a052da3c4c1d48d
Autor:
Nagendrakumar B. Singanallur, Aldo Dekker, Phaedra L. Eblé, Froukje van Hemert-Kluitenberg, Klaas Weerdmeester, Jacquelyn Horsington, Wilna Vosloo W
Publikováno v:
Vaccines, Vol 8, Iss 1, p 80 (2020)
The continuous emergence of foot-and-mouth disease virus (FMDV) serotype A variants in South East Asia is of concern for international FMDV antigen banks, especially when in vitro tests predict a low antigenic match. A vaccination-challenge study was
Externí odkaz:
https://doaj.org/article/4c2d613f12be4e22afa14f5912d9ce6e
Autor:
Aldo Dekker, Beatriz Sanz-Bernardo, Nagendrakumar Balasubramanian Singanallur, Anna B. Ludi, Jacquelyn Horsington, Phaedra L. Eblé, Donald P. King, Wilna Vosloo
Publikováno v:
Vaccines, Vol 8, Iss 1, p 24 (2020)
Since 2015, outbreaks of foot-and-mouth disease (FMD) in the Middle East have been caused by a new emerging viral lineage, A/ASIA/G-VII. Invitro vaccine matching data indicated that this virus poorly matched (low r1-value) with vaccines that were bei
Externí odkaz:
https://doaj.org/article/dfb47020404041dca35a3152b8a72938