Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Aldo Cagnolini"'
Autor:
Wei Zhang, Hui Xiong, Xuan Huang, Aldo Cagnolini, Adam Hoye, Nathaniel Anthony Lim, Carey Horchler
Publikováno v:
Nuclear Medicine and Biology. :S88-S89
Autor:
Aurélie Prignon, Claire Provost, Jean-Noël Talbot, Françoise Montravers, Adrian D. Nunn, Laura E. Lantry, Aldo Cagnolini, Anne Gruaz-Guyon, Valérie Nataf
Publikováno v:
Nuclear Medicine and Biology. 42:92-98
Introduction AMBA is a bombesin analogue that binds to GRPr. In a mouse model of estrogen-dependent human breast cancer, we tested whether 68 Ga-AMBA can be used for PET detection of GRPr-expressing tumors and could be more accurate than 18 F-FDG to
Autor:
Beau Ballard, Tammy L. Rold, Hendrick P. Engelbrecht, Kattesh V. Katti, Aldo Cagnolini, Raghuraman Kannan, Cathy S. Cutler, Charles L. Barnes, Timothy J. Hoffman, Silvia S. Jurisson
Publikováno v:
Nuclear Medicine and Biology. 38:63-76
Introduction Tetradentate acyclic and macrocyclic diphosphine ligands (P 2 N 2 and P 2 S 2 ) have been synthesized and characterized as potential chelates for Rh(III). Methods The coordination complexes [RhCl 2 ( L1 )]Cl, trans -[RhCl 2 ( L2 )]PF 6 ,
Autor:
Laura E. Lantry, Michael F. Tweedle, Adrian D. Nunn, Karen E. Linder, Aldo Cagnolini, Jianqing Chen, Jaclyn Fox, Weiwei Feng, Mary Ellen Maddalena
Publikováno v:
Journal of Nuclear Medicine. 50:2017-2024
(177)Lu-DO3A-CH(2)CO-G-4-aminobenzoyl-Q-W-A-V-G-H-L-M-NH(2) ((177)Lu-AMBA) is a radiolabeled bombesin derivative that is bound and internalized by cells expressing the G-protein-coupled gastrin-releasing peptide receptor (GRP-R) and is currently in p
Autor:
Natarajan Raju, Edmund Metcalfe, Jianqing Chen, Laura E. Lantry, Aldo Cagnolini, Weiwei Feng, Hong Fan, Karen E. Linder, Stephen M. Eaton, Rolf E. Swenson, Adrian D. Nunn, Thangavel Arunachalam
Publikováno v:
Bioconjugate Chemistry. 20:1171-1178
The metabolism of (177)Lu-AMBA (AMBA = DO3A-CH(2)CO-G-(4-aminobenzoyl)-QWAVGHLM-NH(2)), a radiotherapeutic compound in clinical development that binds to GRP and NMB receptors, was studied in vitro (mouse, rat and human plasma, mouse kidney homogenat
Autor:
Jin Xie, Patricia Droege, Todd A. Osiek, Daniel Cohen, Anil S. Modak, David Klug, Silvia S. Jurisson, UmaShanker Sampath, Sofia Touami, Aldo Cagnolini, William C. Putnam, Charles L. Barnes, James K. Bashkin
Publikováno v:
Journal of the Chemical Society, Dalton Transactions. :2049-2058
A variety of 2,2′∶6′,2″-terpyridine (terpy) derivatives modified at the 4′ position has been synthesized to generate bifunctional chelates. A particularly convenient route to these bifunctional chelates, based on nucleophilic substitution o
Autor:
Francesco Tisato, Cristina Bolzati, Giuliano Bandoli, Stefano Gatto, Fiorenzo Refosco, Aldo Cagnolini
Publikováno v:
Journal of the Chemical Society. Dalton transactions
8 (1997): 1421–1427. doi:10.1039/a607584c
info:cnr-pdr/source/autori:Tisato F.; Refosco F.; Bolzati C.; Cagnolini A.; Gatto S.; Bandoli G./titolo:Syntheses and characterisation of rhenium-(III) and-(V) complexes containing aminophosphine ligands. Crystal structures of [Re-V(OCl2)(OMe)L] and [Re-III(Cl3L)(PPh3)], L equals o-(diphenylphosphino)-N,N'-dimethylaniline/doi:10.1039%2Fa607584c/rivista:Journal of the Chemical Society. Dalton transactions (Print)/anno:1997/pagina_da:1421/pagina_a:1427/intervallo_pagine:1421–1427/volume:8
8 (1997): 1421–1427. doi:10.1039/a607584c
info:cnr-pdr/source/autori:Tisato F.; Refosco F.; Bolzati C.; Cagnolini A.; Gatto S.; Bandoli G./titolo:Syntheses and characterisation of rhenium-(III) and-(V) complexes containing aminophosphine ligands. Crystal structures of [Re-V(OCl2)(OMe)L] and [Re-III(Cl3L)(PPh3)], L equals o-(diphenylphosphino)-N,N'-dimethylaniline/doi:10.1039%2Fa607584c/rivista:Journal of the Chemical Society. Dalton transactions (Print)/anno:1997/pagina_da:1421/pagina_a:1427/intervallo_pagine:1421–1427/volume:8
Substitution reactions of labile rhenium(V) precursors with o-(diphenylphosphino)-N,N′ -dimethylaniline, L, gave a series of monooxorhenium(V) complexes of general formula [ReOX 2 Y(L)] (X = Y = Cl 1; X = Cl, Y = OMe 2) and [ReOX 2 (OEt)L] (X = Cl
Autor:
Jianqing Chen, Aldo Cagnolini, Tina Marie Skedzielewski, Kimberly Ramos, Adrian D. Nunn, Laura E. Lantry, Karen E. Linder, Rolf E. Swenson
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 68(12)
Ga-AMBA (Ga-DO3A-CH(2)CO-G-[4-aminobenzoyl]-QWAVGHLM-NH(2)) is a bombesin-like agonist with high affinity for gastrin releasing peptide receptors (GRP-R). Syntheses for (nat)Ga-AMBA, [(67)Ga]Ga-AMBA and [(68)Ga]Ga-AMBA were developed. The preparation
Autor:
Rolf E Swenson, Hanh D Nguyen, Silvio Aime, Karen E Linder, Edmund Metcalfe, Nicola D'Amelio, Aldo Cagnolini
Publikováno v:
Inorganic chemistry. 48(7)
(177)Lu-AMBA (AMBA = DO3A-CH(2)CO-G-[4-aminobenzoyl]-QWAVGHLM-NH(2)) is being developed for the radiotherapeutic treatment of tumors that express the gastrin-releasing peptide receptor (GRP-R). In this study we investigated the fate of the (177)hafni
Autor:
Natarajan Raju, Rolf E. Swenson, Aldo Cagnolini, Michael F. Tweedle, Karen E. Linder, Edmund Metcalfe, Jianqing Chen
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 66(4)
A robust formulation was developed for [ 177 Lu]Lu-AMBA ( 177 Lu-DO3A-CH 2 CO-G-[4-aminobenzoyl]-QWAVGHLM-NH 2 ), a Bombesin-like agonist with high affinity for Gastrin Releasing Peptide (GRP) receptors. During optimization of labeling, the effect of