Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Aldo Alejandro Vilcaes"'
Publikováno v:
Frontiers in Oncology, Vol 5 (2016)
Glycolipids are complex molecules consisting of a ceramide lipid moiety linked to a glycan chain of variable length and structure. Among these are found the gangliosides, which are sialylated glycolipids ubiquitously distributed on the outer layer of
Externí odkaz:
https://doaj.org/article/6476de2fbb1d49d9b1120a321dd9d1c2
Autor:
Jose Luis Daniotti, Aldo Alejandro Vilcaes, Vanina eTorres Demichelis, Fernando Miguel Ruggiero, Macarena eRodriguez-Walker
Publikováno v:
Frontiers in Oncology, Vol 3 (2013)
Altered networks of gene regulation underlie many pathologies, including cancer. There are several proteins in cancer cells that are turned either on or off, which dramatically alters the metabolism and the overall activity of the cell, with the comp
Externí odkaz:
https://doaj.org/article/98fd88ba85fe49fdb2a60afb43a83038
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1063 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 3
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1063 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 3
Gangliosides are constituents of the mammalian cell membranes and participate in the inflammatory response. However, little is known about the presence and enzymatic activity of ganglioside sialyltransferases at the cell surface of macrophages, one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7035565025b4b426460179e5bd346384
https://www.mdpi.com/1422-0067/21/3/1063
https://www.mdpi.com/1422-0067/21/3/1063
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1859:80-93
Gangliosides are glycolipids embedded in the outer leaflets of the plasma membrane. Antibodies against GM1 and GD1a gangliosides are associated with selective dysfunction of motor axons in peripheral neuropathies, and differential endocytic processin
Autor:
Nicholas G. James, David M. Jameson, Ernesto E. Ambroggio, Jose Ignacio Gallea, Maria Soledad Celej, Aldo Alejandro Vilcaes
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The amyloid aggregation of the presynaptic protein α-synuclein (AS) is pathognomonic of Parkinson's disease and other neurodegenerative disorders. Physiologically, AS contributes to synaptic homeostasis by participating in vesicle maintenance, traff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2338fa28a62958a4328d6247395ec0
Wiley Online Library
Wiley Online Library
Publikováno v:
Neuron
Recent studies have investigated the composition and functional effects of extracellular vesicles (EVs) secreted by a variety of cell types. However, the mechanisms underlying the impact of these vesicles on neurotransmission remain unclear. Here, we
Publikováno v:
Biochemical Journal. 470:131-144
Gangliosides are sialic acid-containing glycosphingolipids mainly expressed at the outer leaflet of the plasma membrane. Sialidase NEU3 is a key enzyme in the catabolism of gangliosides with its up-regulation having been observed in human cancer cell
Autor:
Mercedes Lasaga, Patricia Verónica Gonzalez, Ivana Noelia Machado, Teresa Nieves Scimonelli, Lila Carniglia, Helgi B. Schiöth, Aldo Alejandro Vilcaes
Publikováno v:
Brain, Behavior, and Immunity. 46:137-146
The immune system is an important modulator of learning, memory and neural plasticity. Interleukin 1β (IL-1β), a pro-inflammatory cytokine, significantly affects several cognitive processes. Previous studies by our group have demonstrated that intr
Autor:
Natali L. Chanaday, Ana L. De Paul, Aldo Alejandro Vilcaes, Alicia Inés Torres, German A. Roth, Alicia L. Degano
Publikováno v:
Molecular Neurobiology. 51:1353-1367
Experimental autoimmune encephalomyelitis (EAE) is an animal model that mimics many of the clinical and pathological features of the human disease multiple sclerosis (MS). Both are inflammatory demyelinating and neurodegenerative pathologies of the c
Autor:
Teresa Nieves Scimonelli, Helgi B. Schiöth, Mercedes Lasaga, Carla Mariana Caruso, German A. Roth, Ivana Noelia Machado, Patricia Verónica Gonzalez, Aldo Alejandro Vilcaes
Publikováno v:
Brain, Behavior, and Immunity. 34:141-150
Pro-inflammatory cytokines can affect cognitive processes such as learning and memory. Particularly, interleukin-1β (IL-1β) influences the consolidation of hippocampus-dependent memories. We previously reported that administration of IL-1β in dors