Zobrazeno 1 - 10
of 314
pro vyhledávání: '"Aldina, Barral"'
Autor:
Lucas G. Azevedo, Ezequiel Sosa, Artur T.L. de Queiroz, Aldina Barral, Richard J. Wheeler, Marisa F. Nicolás, Leonardo P. Farias, Dario Fernández Do Porto, Pablo Ivan P. Ramos
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 25, Iss , Pp 100538- (2024)
Leishmaniasis, a vector-borne disease, is caused by the infection of Leishmania spp., obligate intracellular protozoan parasites. Presently, human vaccines are unavailable, and the primary treatment relies heavily on systemic drugs, often presenting
Externí odkaz:
https://doaj.org/article/f55a7b0a366841a18ee77bccf5b1fab7
Autor:
Laise de Moraes, Luciane Amorim Santos, Liã Bárbara Arruda, Maria da Purificação Pereira da Silva, Márcio de Oliveira Silva, José Adriano Góes Silva, André Ramos, Marcos Bastos dos Santos, Felipe Guimarães Torres, Cibele Orge, Antonio Marcos dos Santos Teixeira, Thiago Santos Vieira, Laura Ramírez, Manuel Soto, Maria Fernanda Rios Grassi, Isadora Cristina de Siqueira, Dorcas Lamounier Costa, Carlos Henrique Nery Costa, Bruno de Bezerril Andrade, Kevan Akrami, Camila Indiani de Oliveira, Viviane Sampaio Boaventura, Manoel Barral-Netto, Aldina Barral, Anne-Mieke Vandamme, Johan Van Weyenbergh, Ricardo Khouri
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Visceral leishmaniasis is an opportunistic disease in HIV-1 infected individuals, unrecognized as a determining factor for AIDS diagnosis. The growing geographical overlap of HIV-1 and Leishmania infections is an emerging challenge worldwide, as co-i
Externí odkaz:
https://doaj.org/article/3e78c7e78da24aae8e317c5fbadf0e61
Autor:
Sara Nunes, Mariana Rosa Ampuero, Ícaro Bonyek-Silva, Reinan Lima, Filipe Rocha Lima, Sérgio Marcos Arruda, Ricardo Khouri, Pablo Rafael Silveira Oliveira, Aldina Barral, Viviane Sampaio Boaventura, Cláudia Ida Brodskyn, Natalia Machado Tavares
Publikováno v:
Microbiology Research, Vol 12, Iss 4, Pp 765-778 (2021)
Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) amplifies the immune response, operating synergistically with Toll-Like Receptors (TLRs) in the production of inflammatory mediators. TREM-1 signaling depends on the adapter protein DAP12, whi
Externí odkaz:
https://doaj.org/article/c3d91b01911249728e8cbb247a83ceb4
Autor:
Sara Nunes, Rafael Tibúrcio, Icaro Bonyek-Silva, Pablo Rafael Oliveira, Ricardo Khouri, Viviane Boaventura, Aldina Barral, Cláudia Brodskyn, Natalia Machado Tavares
Publikováno v:
Microorganisms, Vol 11, Iss 8, p 1937 (2023)
Skin ulcers of cutaneous leishmaniasis (CL) are characterized by a localized inflammatory response mediated by innate and adaptive immune cells, including dendritic cells (DC) and natural killer (NK) cells. Bidirectional interactions between DCs and
Externí odkaz:
https://doaj.org/article/a6484fb11ba143a2a2597b17d94a83ba
Autor:
Icaro Bonyek-Silva, Thiago Cerqueira-Silva, Sara Nunes, Antônio Fernando Araújo Machado, Márcio Rivison Silva Cruz, Blenda Pereira, Leilane Estrela, Jéssica Silva, Ananda Isis, Aldina Barral, Pablo Rafael Silveira Oliveira, Ricardo Khouri, C. Henrique Serezani, Cláudia Brodskyn, Juliana Ribeiro Caldas, Manoel Barral-Netto, Viviane Boaventura, Natalia Machado Tavares
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
AimsPre-existing conditions, such as age, hypertension, obesity, and diabetes, constitute known risk factors for severe COVID-19. However, the impact of prediabetes mellitus (PDM) on COVID-19 severity is less clear. This study aimed to evaluate the i
Externí odkaz:
https://doaj.org/article/43327780847a41ff914ca9eb3dc8da9d
Autor:
Laise de Moraes, Moyra M. Portilho, Bram Vrancken, Frederik Van den Broeck, Luciane Amorim Santos, Marina Cucco, Laura B. Tauro, Mariana Kikuti, Monaise M. O. Silva, Gúbio S. Campos, Mitermayer G. Reis, Aldina Barral, Manoel Barral-Netto, Viviane Sampaio Boaventura, Anne-Mieke Vandamme, Kristof Theys, Philippe Lemey, Guilherme S. Ribeiro, Ricardo Khouri
Publikováno v:
Viruses, Vol 15, Iss 6, p 1236 (2023)
The Americas, particularly Brazil, were greatly impacted by the widespread Zika virus (ZIKV) outbreak in 2015 and 2016. Efforts were made to implement genomic surveillance of ZIKV as part of the public health responses. The accuracy of spatiotemporal
Externí odkaz:
https://doaj.org/article/abe6a6e6d445417dbd46758a79f7518d
Autor:
Lucas Gentil Azevedo, Artur Trancoso Lopo de Queiroz, Aldina Barral, Luciane Amorim Santos, Pablo Ivan Pereira Ramos
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Leishmania spp. are digenetic parasites capable of infecting humans and causing a range of diseases collectively known as leishmaniasis. The main mechanisms involved in the development and permanence of this pathology are linked t
Externí odkaz:
https://doaj.org/article/8087bf1b3c5c4fb48f2de855a9f133aa
Autor:
Gaurav Gupta, Zhirong Mou, Ping Jia, Rohit Sharma, Romaniya Zayats, Sayonara M. Viana, Lianyu Shan, Aldina Barral, Viviane S. Boaventura, Thomas T. Murooka, Abdel Soussi-Gounni, Camila I. de Oliveira, Jude E. Uzonna
Publikováno v:
Cell Reports, Vol 33, Iss 11, Pp 108513- (2020)
Summary: The long pentraxin 3 (PTX3) plays a critical role in inflammation, tissue repair, and wound healing. Here, we show that PTX3 regulates disease pathogenesis in cutaneous leishmaniasis (CL). PTX3 expression increases in skin lesions in patient
Externí odkaz:
https://doaj.org/article/aaefd71d64124fd1a867b9f493e7fb4a
Autor:
Fabine Correia Passos, Marcelo Biondaro Gois, Adenilma Duranes Sousa, Ananda Isis Lima de Marinho, Laura Corvo, Manoel Soto, Manoel Barral-Netto, Aldina Barral, Gyselle Chrystina Baccan
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 115 (2020)
BACKGROUND Visceral leishmaniasis (VL) is a tropical neglected disease with high associated rates of mortality. Several studies have highlighted the importance of the intestinal tract (IT) and gut microbiota (GM) in the host immunological defense. Da
Externí odkaz:
https://doaj.org/article/951ed3c8279f4509a2991a83128aa536
Autor:
Laise de Moraes, Thiago Cerqueira-Silva, Victor Nobrega, Kevan Akrami, Luciane Amorim Santos, Cibele Orge, Paula Casais, Lais Cambui, Rita de Cássia Pontello Rampazzo, Karen Soares Trinta, Camila Amato Montalbano, Maria Jania Teixeira, Luciano Pamplona Cavalcante, Bruno B Andrade, Rivaldo Venâncio da Cunha, Marco Aurélio Krieger, Manoel Barral-Netto, Aldina Barral, Ricardo Khouri, Viviane Sampaio Boaventura
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008467 (2020)
BackgroundChikungunya virus (CHIKV) has caused worldwide epidemics that impose a major burden on health systems. Approximately half of infected individuals develop chronic debilitating arthralgia, affecting their quality of life. Here, we identified
Externí odkaz:
https://doaj.org/article/377d9bca763748ebbb19d48e6fd7a70a