Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Alden Chesney"'
Autor:
Christine V. Ichim, Dzana D. Dervovic, Lap Shu Alan Chan, Claire J. Robertson, Alden Chesney, Marciano D. Reis, Richard A. Wells
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background In patients with myelodysplastic syndrome (MDS), bone marrow cells have an increased predisposition to apoptosis, yet MDS cells outcompete normal bone marrow (BM)-- suggesting that factors regulating growth potential may be import
Externí odkaz:
https://doaj.org/article/fbc3d6ab0ce744d1904623f21be58db7
Autor:
Andrey Mikheikin, Anita Olsen, Kevin Leslie, Freddie Russell-Pavier, Andrew Yacoot, Loren Picco, Oliver Payton, Amir Toor, Alden Chesney, James K. Gimzewski, Bud Mishra, Jason Reed
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Physical mapping of DNA can be used to detect structural variants and for whole-genome haplotype assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘nanomap’ single molecules of DNA.
Externí odkaz:
https://doaj.org/article/a68808d05e344a9c825d7924d933f9bc
Publikováno v:
Journal of Pathology Informatics, Vol 12, Iss 1, Pp 23-23 (2021)
Objectives: Bone marrow evaluation plays a critical role in the diagnosis, staging, and monitoring of many diseases. Although there are standardized guidelines for assessing bone marrow specimen quality, there is a lack of evidence-based tools to per
Externí odkaz:
https://doaj.org/article/cd4d49629c9b40698430924f0f1d777c
Autor:
Konstantin Krutikov, Yanzhen Zheng, Alden Chesney, Xiaoyong Huang, Andrea K Vaags, Valentina Evdokimova, Margaret R Hough, Edwin Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89649 (2014)
The noncluster homeobox gene HOX11/TLX1 (TLX1) is detected at the breakpoint of the t(10;14)(q24;q11) chromosome translocation in patients with T cell acute lymphoblastic leukemia (T-ALL). This translocation results in the inappropriate expression of
Externí odkaz:
https://doaj.org/article/d4093994f8354e139ac437ecf8a0a81d
PDF file - 69K, Engraftment of CD19+CD5+ CLL cells in peritoneal cavity: Absolute count (x105 cells) of CD19+CD5+ CLL cells in the peritoneal cavity of animals receiving either sCD200hi CLL plasma, or sCD200 absorbed CLL plasma in the presence or abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354ee6a736bb2de38caaada21d38bcfc
https://doi.org/10.1158/0008-5472.22393917
https://doi.org/10.1158/0008-5472.22393917
PDF file - 66K, 6.Engraftment of CD19+CD5+ CLL cells in peritoneal cavity: Absolute count (x105 cells) of CD19+CD5+ CLL cells in the peritoneal cavity of animals receiving one of the three plasma infusions: sCD200hi CLL plasma, sCD200hi CLL plasma +
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3462fa27c43a120c718bbbf5606764a5
https://doi.org/10.1158/0008-5472.22393923.v1
https://doi.org/10.1158/0008-5472.22393923.v1
PDF file - 151K, Engraftment of human CLL and T cells in the peritoneal cavity of anti-CD200 treated, Rituxan treated, or untreated animals: Frequencies of CD19+CD5+ CLL cells (left column) and CD4+ and CD8+ T cells (right column) in the peritoneal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc274313b72e81df240de8984703e476
https://doi.org/10.1158/0008-5472.22393914.v1
https://doi.org/10.1158/0008-5472.22393914.v1
PDF file - 181K, Comparison of CD40, CD20, CD38, and CD49d expression on CLL cells engrafted in NOD.SCIDgammacnull mice and CLL cells from original spleen: Expression of CD40, CD20, CD38, and CD49d on cells gated on human CD45 expression from Sp6 (or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d5d1d6346cbf761a56472786f07a07
https://doi.org/10.1158/0008-5472.22393929.v1
https://doi.org/10.1158/0008-5472.22393929.v1
PDF file - 125K, Engraftment of CD19+CD5+ CLL cells in peritoneal cavity: CD19+CD5+ CLL cells within the CD45+ population in the peritoneal cavity of mice that received one of three plasma infusions: sCD200lo normal plasma (upper panel), sCD200hi CLL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474b50923edcec76f9175420f29c1a59
https://doi.org/10.1158/0008-5472.22393920
https://doi.org/10.1158/0008-5472.22393920
CD200 is a transmembrane molecule with an important immunoregulatory role that is overexpressed on most chronic lymphocytic leukemia (CLL) cells. In this study, we characterized a previously unknown soluble form of this molecule in human plasma terme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84c710239a6dce118c1bc1bb3b9033e2
https://doi.org/10.1158/0008-5472.c.6503910.v1
https://doi.org/10.1158/0008-5472.c.6503910.v1