Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Aldehyde oxidase 1"'
Akademický článek
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Autor:
Claudia Garrido, Silke Leimkuehler
Publikováno v:
Drug Metabolism and Disposition. 49:729-735
Mammalian aldehyde oxidases (AOX) are molybdo-flavoenzymes of pharmacological and pathophysiologic relevance that are involved in phase I drug metabolism and, as a product of their enzymatic activity, are also involved in the generation of reactive o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab69525eb38d0baf1072ac9b13ec1181
https://doi.org/10.1124/dmd.121.000549
https://doi.org/10.1124/dmd.121.000549
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Yongli Guo, Shuai Xu, Yongbo Yu, Yuanhu Liu, Qiaoyin Liu, Xin Ni, Yeran Yang, Shengcai Wang, Jie Zhang, Nian Sun, Yanzhen Li, Xuexi Zhang
Publikováno v:
Transl Pediatr
Background Thyroid carcinoma is a common pediatric head and neck cancer, of which papillary thyroid cancer (PTC) is the most common type. Previously, we found that thyroid peroxidase (TPO) and aldehyde oxidase 1 (AOX1) were differentially expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fc65293bf552e4028560185ea269f8
https://doi.org/10.21037/tp-20-301
https://doi.org/10.21037/tp-20-301
Publikováno v:
Clinica Chimica Acta. 504:168-171
Xanthinuria is a rare genetic metabolic disorder, the biochemical mechanism of xanthinuria is the disturbance of purine to uric acid metabolism due to the deficiency of xanthine dehydrogenase/xanthine oxidase (XDH/XO) and aldehyde oxidase 1 (AOX1). X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f259949b54b8756588e799451f2d7b97
https://doi.org/10.1016/j.cca.2020.02.012
https://doi.org/10.1016/j.cca.2020.02.012
Autor:
Yan-Hong Deng, Hong Ren, Shuang Xiao, Neng Shen, Huadong Tang, Peng Hu, Mingli Peng, Yong Sun
Publikováno v:
International immunopharmacology. 101
Our previous studies demonstrated that Curc-mPEG454, a curcumin derivative modified with short-chain polyethylene glycol (PEG), not only increased the blood concentration of curcumin, but also retained its anti-inflammatory activity. Here, we aimed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9152c23e596e0ea8afed0eab78460fd
https://pubmed.ncbi.nlm.nih.gov/34628270
https://pubmed.ncbi.nlm.nih.gov/34628270
Autor:
Jonathan G. L. Mullins, Karl Austin-Muttitt, Shiyan Chen, Linghua Harris Zhang, Aik Jiang Lau
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 371:75-86
Tamoxifen, raloxifene, and nafoxidine are selective estrogen receptor modulators (SERMs) reported to inhibit the catalytic activity of human aldehyde oxidase 1 (AOX1). How these drugs interact with AOX1 and whether other SERMs inhibit this drug-metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395f34d59c0bad1e3a3940b3948c1c3d
https://doi.org/10.1124/jpet.119.259267
https://doi.org/10.1124/jpet.119.259267
Autor:
Hyunsoo Kim, Jeong-Oog Lee, Eunji Kim, Han Gyung Kim, Jae Youl Cho, Kon Kuk Shin, Mohammad Amjad Hossain, Eunju Choi, Deok Jeong, Yo Han Hong, Donghyun Kim, Young-Su Yi
Publikováno v:
Journal of Ginseng Research, Vol 43, Iss 1, Pp 154-160 (2019)
Background: Compound K (CK) is an active metabolite of ginseng saponin, ginsenoside Rb1, that has been shown to have ameliorative properties in various diseases. However, its role in inflammation and the underlying mechanisms are poorly understood. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e0ff0481a5f592cfad16ee9b4579c3
https://doi.org/10.1016/j.jgr.2018.10.003
https://doi.org/10.1016/j.jgr.2018.10.003
Autor:
Lauren A. Hauser, Marek Napierala, Amanda Clark, Jennifer M. Farmer, Kimal Rajapakshe, David A. Lynch, Peining Xu, Clementina Mesaros, Dean P. Edwards, Yu-Yun Chen, Ian A. Blair, Shixia Huang, Cristian Coarfa, Jill S. Napierala
Publikováno v:
Molecular & Cellular Proteomics : MCP
Identifying biomarkers is important for assessment of disease progression, prediction of symptom development, and determination of treatment effectiveness. While unbiased analyses of differential gene expression using next-generation sequencing metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239d5431dbcbfd7df7c1a470624aee8d
http://europepmc.org/articles/PMC8214145
http://europepmc.org/articles/PMC8214145
Autor:
Karthic Rajamanickam, Jian Yang, Benjamin Heng, Meena Kishore Sakharkar, Sarinder Kaur Dhillon, Gilles J. Guillemin, Nady Braidy
Publikováno v:
International Journal of Tryptophan Research : IJTR
International Journal of Tryptophan Research, Vol 13 (2020)
International Journal of Tryptophan Research, Vol 13 (2020)
Tryptophan metabolism plays essential roles in both immunomodulation and cancer development. Indoleamine 2,3-dioxygenase, a rate-limiting enzyme in the metabolic pathway, is overexpressed in different types of cancer. To get a better understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f1f09b4213f4199bfe18c486322a26
http://europepmc.org/articles/PMC7734567
http://europepmc.org/articles/PMC7734567