Zobrazeno 1 - 10
of 1 119
pro vyhledávání: '"Aldehyde dehydrogenase 2"'
Autor:
Simin ZHANG, Fazhi QI
Publikováno v:
Zhongguo Linchuang Yixue, Vol 31, Iss 5, Pp 724-733 (2024)
ObjectiveTo verify the role of aldehyde dehydrogenase 2 (ALDH2) in wound healing and to explore the underlying mechanisms. MethodsA murine excisional wound model was developed and mice were randomly assigned to control group and Alda-1 (ALDH2 agonist
Externí odkaz:
https://doaj.org/article/3874d1a8995b4e52b01d8011089388eb
Autor:
Han Liu, Bingchen Jiang, Rui Hua, Xuehao Liu, Bao Qiao, Xiangxin Zhang, Xilong Liu, Wenjun Wang, Qiuhuan Yuan, Bailu Wang, Shujian Wei, Yuguo Chen
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are now recommended for patients with heart failure, but the mechanisms that underlie the protective role of SGLT2i in cardiac remodeling remain unclear. Aldehyde dehydrogenase 2
Externí odkaz:
https://doaj.org/article/53dfa8dfb86c418596c46e2faf05375e
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 3591-3600 (2024)
Youqian Li,1,2 Wei Zhong,1,2 Zhidong Liu,1,2 Changjing Huang,1,2 Junyin Peng,1,2 Hanlin Li1,2 1Center for Cardiovascular Diseases, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of China; 2Guangdong Pro
Externí odkaz:
https://doaj.org/article/fb5f9e7bf51242e09347b287d6be6bf3
Autor:
Freeborn Rwere, Joseph R. White, Rafaela C. R. Hell, Xuan Yu, Xiaocong Zeng, Leslie McNeil, Kevin N. Zhou, Martin S. Angst, Che-Hong Chen, Daria Mochly-Rosen, Eric R. Gross
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Aldehyde dehydrogenase 2 (ALDH2) is critical for alcohol metabolism by converting acetaldehyde to acetic acid. In East Asian descendants, an inactive genetic variant in ALDH2, rs671, triggers an alcohol flushing response due to ac
Externí odkaz:
https://doaj.org/article/5332530b9af0442aabb1515ef3b4fc22
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 6, Pp 684-692 (2024)
ABSTRACT Aims The aim of this study was to better understand how the chemotherapy drug doxorubicin contributes to the development of β‐cell dysfunction and to explore its relationship with mitochondrial aldehyde dehydrogenase‐2 (ALDH2). Material
Externí odkaz:
https://doaj.org/article/19eb8ed8b1574309887ca802bf57cd69
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundThe aldehyde dehydrogenase 2 (ALDH2) rs671 (A) allele has been implicated in neurodegeneration, potentially through oxidative and inflammatory pathways. The study aims to investigate the effects of the ALDH2 rs671 (A) allele and high sensit
Externí odkaz:
https://doaj.org/article/dab495501bc24da78f8b8692bac70500
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 2407-2415 (2024)
Hui Rao,1 Xianfang Wang,2 Yu Luo,3 Liu Liang,1 Wei Ye,1 Xuemin Guo1 1Department of Laboratory Medicine, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of China; 2Center for Cardiovascular Diseases, Meiz
Externí odkaz:
https://doaj.org/article/dc393798bb0642579b08b04d39a7c321
Publikováno v:
International Journal of General Medicine, Vol Volume 16, Pp 5719-5727 (2023)
Miao Zeng,1,2,* Yiping Liu,1,2,* Yunquan Xie1,2 1Department of Laboratory Medicine, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of China; 2Center for Precision Medicine, Meizhou People’s Ho
Externí odkaz:
https://doaj.org/article/666566be930e4d748dd6bf47d5376cd1
Autor:
Mikiko Tokiya, Manabu Hashimoto, Kenji Fukuda, Kazuhiro Kawamoto, Chiho Akao, Mariko Tsuji, Yusuke Yakushiji, Haruki Koike, Akiko Matsumoto
Publikováno v:
Environmental Health and Preventive Medicine, Vol 29, Pp 55-55 (2024)
Background: The East Asian-specific genetic diversity, the rs671 variant of aldehyde dehydrogenase 2, causes the “Asian flush” phenomenon following alcohol consumption, resulting in an alcohol avoidance phenotype. The variant is suggested as a ri
Externí odkaz:
https://doaj.org/article/29446cd6a857439eb215772a94a57399
Autor:
Hui‐Tzu Chien, Chia‐Lung Tsai, Chi‐Kuan Young, Yun‐Shien Lee, Chun‐Ta Liao, Chih‐Ching Yeh, Angel Chao, Kai‐Lun Cho, Ching‐Han Chen, Shiang‐Fu Huang
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 19174-19187 (2023)
Abstract Introduction In the era of precision preventive medicine, susceptible genetic markers for oro‐/hypopharyngeal squamous cell carcinoma (OPSCC) have been investigated for genome‐wide associations. Materials and Methods A case–control stu
Externí odkaz:
https://doaj.org/article/104d8a84db014219a063c35fd7ddc6cd