Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alcira Fynn"'
Autor:
Christine von Neuhoff, Dirk Reinhardt, Yves Bertrand, Kim Klein, Sarah Elitzur, Jonas Abrahamsson, Guy Leverger, Jacqueline Cloos, Ursula Creutzig, Valerie de Haas, Romy E. Van Weelderen, Pter Smisek, Martin Zimmermann, Henrik Hasle, Brenda Gibson, Alcira Fynn, Bassem I. Razzouk, Alexei Maschan, Shau Yin Ha, Michael Dworzak, Christine J. Harrison, H. Berna Beverloo, Carmelo Rizzari, Gertjan J.L. Kaspers, Susana C. Raimondi
Publikováno v:
Pediatric Blood and Cancer, 69(1):e29341. Wiley-Liss Inc.
Klein, K, Beverloo, H B, Zimmermann, M, Raimondi, S C, von Neuhoff, C, de Haas, V, van Weelderen, R, Cloos, J, Abrahamsson, J, Bertrand, Y, Dworzak, M, Fynn, A, Gibson, B, Ha, S Y, Harrison, C J, Hasle, H, Elitzur, S, Leverger, G, Maschan, A, Razzouk, B, Reinhardt, D, Rizzari, C, Smisek, P, Creutzig, U & Kaspers, G J L 2022, ' Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia : A retrospective cohort study of the Relapsed AML 2001/01 Study ', Pediatric Blood and Cancer, vol. 69, no. 1, e29341 . https://doi.org/10.1002/pbc.29341
Klein, K, Beverloo, H B, Zimmermann, M, Raimondi, S C, von Neuhoff, C, de Haas, V, van Weelderen, R, Cloos, J, Abrahamsson, J, Bertrand, Y, Dworzak, M, Fynn, A, Gibson, B, Ha, S-Y, Harrison, C J, Hasle, H, Elitzur, S, Leverger, G, Maschan, A, Razzouk, B, Reinhardt, D, Rizzari, C, Smisek, P, Creutzig, U & Kaspers, G J L 2022, ' Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia : A retrospective cohort study of the Relapsed AML 2001/01 Study ', Pediatric Blood & Cancer, vol. 69, no. 1, e29341 . https://doi.org/10.1002/pbc.29341
Klein, K, Beverloo, H B, Zimmermann, M, Raimondi, S C, von Neuhoff, C, de Haas, V, van Weelderen, R, Cloos, J, Abrahamsson, J, Bertrand, Y, Dworzak, M, Fynn, A, Gibson, B, Ha, S Y, Harrison, C J, Hasle, H, Elitzur, S, Leverger, G, Maschan, A, Razzouk, B, Reinhardt, D, Rizzari, C, Smisek, P, Creutzig, U & Kaspers, G J L 2022, ' Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia : A retrospective cohort study of the Relapsed AML 2001/01 Study ', Pediatric Blood and Cancer, vol. 69, no. 1, e29341 . https://doi.org/10.1002/pbc.29341
Klein, K, Beverloo, H B, Zimmermann, M, Raimondi, S C, von Neuhoff, C, de Haas, V, van Weelderen, R, Cloos, J, Abrahamsson, J, Bertrand, Y, Dworzak, M, Fynn, A, Gibson, B, Ha, S-Y, Harrison, C J, Hasle, H, Elitzur, S, Leverger, G, Maschan, A, Razzouk, B, Reinhardt, D, Rizzari, C, Smisek, P, Creutzig, U & Kaspers, G J L 2022, ' Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia : A retrospective cohort study of the Relapsed AML 2001/01 Study ', Pediatric Blood & Cancer, vol. 69, no. 1, e29341 . https://doi.org/10.1002/pbc.29341
BACKGROUND: In addition to treatment response, cytogenetic and molecular aberrations are the most important prognostic factors in children with de novo acute myeloid leukemia (AML). However, little is known about cytogenetics at the time of relapse.M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803fea05029ddfdbff93d7ee929a6a32
https://www.ncbi.nlm.nih.gov/pubmed/34532968
https://www.ncbi.nlm.nih.gov/pubmed/34532968
Autor:
Erik Forestier, Ursula Creutzig, Oussama Abla, Shuhong Shen, Yinmei Zhou, H. Berna Beverloo, Nadine Van Roy, Vincent Lee, Laura Rodriguez, Franco Locatelli, Michael Dworzak, Sarah Elitzur, Anne Auvrignon, Daisuke Tomizawa, Tai Tsung Chang, Dirk Reinhardt, Allen Eng Juh Yeoh, Henrik Hasle, Alcira Fynn, Hiroto Inaba, Susana C. Raimondi, Eveline S. J. M. de Bont, Riccardo Masetti, Martin Zimmermann, Takashi Taga, Souichi Adachi, Barbara De Moerloose, Der Cherng Liang
Publikováno v:
Inaba, H, Zhou, Y, Abla, O, Adachi, S, Auvrignon, A, Beverloo, H B, de Bont, E, Chang, T-T, Creutzig, U, Dworzak, M, Elitzur, S, Fynn, A, Forestier, E, Hasle, H, Liang, D-C, Lee, V, Locatelli, F, Masetti, R, De Moerloose, B, Reinhardt, D, Rodriguez, L, Van Roy, N, Shen, S, Taga, T, Tomizawa, D, Yeoh, A E J, Zimmermann, M & Raimondi, S C 2015, ' Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia : a retrospective international study ', Blood, vol. 126, no. 13, pp. 1575-84 . https://doi.org/10.1182/blood-2015-02-629204
Blood, 126(13), 1575-1584. American Society of Hematology
Blood, 126(13), 1575-1584. AMER SOC HEMATOLOGY
Blood, 126(13), 1575-1584. American Society of Hematology
Blood, 126(13), 1575-1584. AMER SOC HEMATOLOGY
Comprehensive clinical studies of patients with acute megakaryoblastic leukemia (AMKL) are lacking. We performed an international retrospective study on 490 patients (age 50 chromosomes (n=44, 11.8%). Chromosome gain occurred in 195 of 372 (52.4%) pa
Autor:
M. Rapetti, Maria Silvia Larroude, M. Alvarez Bollea, Adriana Arizo, K. Muller, G. Pujal, Marta Dragosky, Norberto Guelbert, A. Degano, Gabriel Aguilar, Leonardo Feldman, Hugo Robledo, Sandra Zirone, Graciela Elena, A. Albina, R. Jaureguiberry, Alba A Ruiz, M. Slago, Andrea Schenone, Juan Jose Chain, G. Galvan, Nora Watman, Gustavo L. Kantor, Alcira Fynn, Julieta Bietti, P. Reichel, N. Fernandez Escobar, Guillermo Drelichman, R. Fernandez, F. Del Rio, M. Marquez, Alejandra Maro, Marcela A Aznar, G. Zarate, Ignacio Rossi, M.A. Barbieri, V. Bacciedoni, M. Bolesina, H. Arrocena, I. Fernandez, Nora Basack, G. Fernandez, G. Buchovsky, V. Lanza, María Fernanda Cuello, S. E. Veber
Publikováno v:
Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. 19(4)
The purpose of this study was to evaluate the frequency of osteoporosis (OP) in patients with Gaucher disease (GD) in Argentina. GD patients from 28 centers were consecutively included from April 2012 to 2014. Bone mineral density (BMD) was determine
Autor:
Todd A. Alonzo, Christine J. Harrison, Dirk Reinhardt, Anne Auvrignon, H. Berna Beverloo, Carmen Salgado, Jacqueline Cloos, Jeffrey E. Rubnitz, Donna L. Johnston, Akio Tawa, Vincent Lee, Ardine Reedijk, Mathilda L. Bongers, Erik Forestier, Walentyna Balwierz, Martin Zimmerman, Bernward Zeller, Barbara De Moerloose, Michael Dworzak, Gertjan J.L. Kaspers, Andrea Pession, Alexander Popa, Ursula Creutzig, Michal Zapotocky, Kim Klein, Betsy A. Hirsch, Takashi Taga, Brenda Gibson, Alcira Fynn, Susana C. Raimondi
Publikováno v:
Journal of Clinical Oncology, 33(36), 4247-+. American Society of Clinical Oncology
Journal of Clinical Oncology, 33(36), 4247-4258. American Society of Clinical Oncology
Klein, K, Kaspers, G, Harrison, C J, Beverloo, HB, Reedijk, A, Bongers, M, Cloos, J, Pession, A, Reinhardt, D, Zimmerman, M, Creutzig, U, Dworzak, M, Alonzo, T, Johnston, D, Hirsch, B, Zapotocky, M, De Moerloose, B, Fynn, A, Lee, V, Taga, T, Tawa, A, Auvrignon, A, Zeller, B, Forestier, E, Salgado, C, Balwierz, W, Popa, A, Rubnitz, J, Raimondi, S & Gibson, B 2015, ' Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Munster Study Group ', Journal of Clinical Oncology, vol. 33, no. 36, pp. 4247-4258 . https://doi.org/10.1200/JCO.2015.61.1947
Journal of Clinical Oncology, 33(36), 4247-4258. American Society of Clinical Oncology
Klein, K, Kaspers, G, Harrison, C J, Beverloo, HB, Reedijk, A, Bongers, M, Cloos, J, Pession, A, Reinhardt, D, Zimmerman, M, Creutzig, U, Dworzak, M, Alonzo, T, Johnston, D, Hirsch, B, Zapotocky, M, De Moerloose, B, Fynn, A, Lee, V, Taga, T, Tawa, A, Auvrignon, A, Zeller, B, Forestier, E, Salgado, C, Balwierz, W, Popa, A, Rubnitz, J, Raimondi, S & Gibson, B 2015, ' Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Munster Study Group ', Journal of Clinical Oncology, vol. 33, no. 36, pp. 4247-4258 . https://doi.org/10.1200/JCO.2015.61.1947
Purpose This retrospective cohort study aimed to determine the predictive relevance of clinical characteristics, additional cytogenetic aberrations, and cKIT and RAS mutations, as well as to evaluate whether specific treatment elements were associate
Autor:
Christine J. Harrison, Dirk Reinhardt, Guy Leverger, Martin Zimmermann, Ursula Creutzig, Valerie de Haas, Brenda Gibson, Kim Klein, Alcira Fynn, Alexey Maschan, Romy van Weelderen, Bassem I. Razzouk, Henrik Hasle, Gertjan J.L. Kaspers, Jonas Abrahamsson, Susana C. Raimondi, Michael Dworzak, Yves Bertrand, Shau Yin Ha, Jacqueline Cloos, Petr Smisek, Christine von Neuhoff, Carmelo Rizzari, Sarah Elitzur, Berna Beverloo
Publikováno v:
Blood. 128:2896-2896
Introduction After treatment response, cytogenetics and molecular aberrations are the most important prognostic factors in children with de novo acute myeloid leukemia (AML). However, little is known about the impact of cytogenetics at relapse. This
Autor:
Batia Stark, Ichiro Tsukimoto, Marry M. van den Heuvel-Eibrink, Gertjan J.L. Kaspers, Charlotte M. Niemeyer, Ursula Creutzig, Natalia N. Savva, Erik Forestier, Martin Zimmermann, Dirk Reinhardt, Franco Locatelli, Bassem I. Razzouk, Alcira Fynn, Anne Auvrignon, Stefan Suciu, Jochen Harbott, Oskar A. Haas, Yaddanapudi Ravindranath, Henrik Hasle, William G. Woods, Christine J. Harrison, Susana C. Raimondi, Todd A. Alonzo, Peter Noellke, Dorora Wojcik, Myron Chang, C Behar, David Webb, Nyla A. Heerema, Alexandra Fischer, Sophia Polychronopoulou
Publikováno v:
Hasle, H, Alonzo, T A & Auvrignon, A 2007, ' Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia: an international retrospective study. ', Blood, vol. 109, no. 11, pp. 4641-7 . https://doi.org/10.1182/blood-2006-10-051342
Hasle, H, Alonzo, T A, Auvrignon, A, Behar, C, Chang, M, Creutzig, U, Fischer, A, Forestier, E, Fynn, A, Haas, O A, Harbott, J, Harrison, C J, Heerema, N A, Van Den Heuvel-Eibrink, M M, Kaspers, G J L, Locatelli, F, Noellke, P, Polychronopoulou, S, Ravindranath, Y, Razzouk, B, Reinhardt, D, Savva, N N, Stark, B, Suciu, S, Tsukimoto, I, Webb, D K, Wojcik, D, Woods, W G, Zimmermann, M, Niemeyer, C M & Raimondi, S C 2007, ' Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia : An international retrospective study ', Blood, vol. 109, no. 11, pp. 4641-4647 . https://doi.org/10.1182/blood-2006-10-051342
Blood, 109(11), 4641-4647. American Society of Hematology
Hasle, H, Alonzo, T A, Auvrignon, A, Behar, C, Chang, M, Creutzig, U, Fischer, A, Forestier, E, Fynn, A, Haas, O A, Harbott, J, Harrison, C J, Heerema, N A, Van Den Heuvel-Eibrink, M M, Kaspers, G J L, Locatelli, F, Noellke, P, Polychronopoulou, S, Ravindranath, Y, Razzouk, B, Reinhardt, D, Savva, N N, Stark, B, Suciu, S, Tsukimoto, I, Webb, D K, Wojcik, D, Woods, W G, Zimmermann, M, Niemeyer, C M & Raimondi, S C 2007, ' Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia : An international retrospective study ', Blood, vol. 109, no. 11, pp. 4641-4647 . https://doi.org/10.1182/blood-2006-10-051342
Blood, 109(11), 4641-4647. American Society of Hematology
Monosomy 7 (−7) and deletion 7q \del(7q)] are rare in childhood acute myeloid leukemia (AML). We retrospectively collected data on 258 children with AML or refractory anemia with excess blasts in transformation (RAEB-T) and −7 or del(7q) with or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95305fd89113d9c2a38ad9b5fa5c3ee0
https://pure.au.dk/portal/da/publications/monosomy-7-and-deletion-7q-in-children-and-adolescents-with-acute-myeloid-leukemia-an-international-retrospective-study(1f5b6a10-d4c6-11dc-abe4-000ea68e967b).html
https://pure.au.dk/portal/da/publications/monosomy-7-and-deletion-7q-in-children-and-adolescents-with-acute-myeloid-leukemia-an-international-retrospective-study(1f5b6a10-d4c6-11dc-abe4-000ea68e967b).html
Autor:
Gertjan J.L. Kaspers, Henrik Hasle, Daniela Diverio, Christine Ragu, Brenda Gibson, Andrea Pession, Sarah Elitzur, Alcira Fynn, Jutte van der Werff ten Bosch, Franco Locatelli, David Grimwade, Anna Maria Testi, Owen P. Smith
Publikováno v:
Blood. 126:563-563
The combined treatment of all-trans retinoic acid (ATRA) and anthracyclines at high cumulative doses (>500-600 mg/m2) is associated with good outcomes in adults and children with acute promyelocytic leukemia (APL). However, high cumulative anthracycl
Autor:
Erik Forestier, H. Berna Beverloo, Shuhong Shen, Anne Auvrignon, Yinmei Zhou, Oussama Abla, Allen Eng Juh Yeoh, Hiroto Inaba, Susana C. Raimondi, Dirk Reinhardt, Souichi Adachi, Alcira Fynn, Barbara De Moerloose, Laura Rodriguez, Franco Locatelli, Tai-Tsung Chang, Michael Dworzak, Henrik Hasle, Martin Zimmermann, Takashi Taga, Der-Cherng Liang, Vincent Lee, Ursula Creutzig, Nicole Dastugue, Daisuke Tomizawa, Sarah Elitzur, Riccardo Masetti, Eveline S. J. M. de Bont
Publikováno v:
Blood. 124:3670-3670
Acute megakaryoblastic leukemia (AMKL) comprises up to 10% of childhood acute myeloid leukemia (AML) cases. However, no large-scale studies have comprehensively evaluated the clinical characteristics and outcomes of patients with AMKL. We performed a
Autor:
Andrea Pession, Gertjan J.L. Kaspers, Ardine Reedijk, Berna Beverloo, Jeffrey E. Rubnitz, Alexander Popa, Michael Dworzak, Akio Tawa, Bernward Zeller, Michal Zapotocky, Anne Auvrignon, Brenda Gibson, Donna L. Johnston, Alcira Fynn, Vincent Lee, Christine J. Harrison, Ursula Creutzig, Takashi Taga, Kim Klein, Carmen Salgado, Martin Zimmermann, Todd A. Alonzo, Mathilda L. Bongers, Walentyna Balwierz, Barbara De Moerloose, Jacqueline Cloos, Dirk Reinhardt
Publikováno v:
Blood. 124:481-481
Introduction Whilst pediatric t(8;21)-positive AML has an overall survival rate of up to 80-90%, the relapse rate at 30-40% remains unacceptably high. Factors that reliably discriminate between patients with t(8;21) who do or do not relapse have been
Autor:
Luis Aversa, Cecilia Riccheri, Mercedes Tomasetti, Monica Makiya, Sergio Gomez, Marcela Gutiérrez, Sandra Zirone, Horacio Caferri, Nestor Rossi, Carlos Hollmann, Daniel Freigeiro, Alcira Fynn, Virginia Schuttenberg, Guillermo Arbesu, David Veron, Constanza Drozdowski, Graciela Elena, Alejandra Cedola, Julieta Bietti, Bibiana Tramunt
Publikováno v:
Blood. 120:2605-2605
Abstract 2605 Introduction: The outcome in pediatric patients with relapse-refractory acute leukemia (acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML)) is very poor. Clofarabine is an active agent in this high risk group. Purpose: