Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alcino Jorge Leitão"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 249 (2023)
To explore the molecular mechanisms underlying the anti-inflammatory activity of (R)-(-)-carvone, we evaluated its ability to inhibit the signaling pathways involving the mitogen-activated protein kinases (MAPKs) and the transcription factor, nuclear
Externí odkaz:
https://doaj.org/article/ee24ef4e8e884a888aaf285a85004c61
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 777 (2021)
The signaling pathways involved in age-related inflammation are increasingly recognized as targets for the development of preventive and therapeutic strategies. Our previous study elucidated the structure–activity relationship of monoterpene compou
Externí odkaz:
https://doaj.org/article/a8309c0140c343249ff3c374fb1eeabc
Autor:
Gabriela Moço, Cátia Sousa, Ana Capitão, Stephen Scott MacKinnon, Alcino Jorge Leitão, Alexandrina Ferreira Mendes
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2263
Volume 24
Issue 3
Pages: 2263
The chemical modification of natural compounds is a promising strategy to improve their frequently poor bioavailability and low potency. This study aimed at synthesizing chemical derivatives of carvone, a natural monoterpene with anti-inflammatory pr