Method validation for simultaneous determination of atropine, pralidoxime and 12 organophosphorus compounds in blood samples by means of high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS)

Autor: Fabrício Souza Pelição, Mariana Dadalto Peres, Graziany Leite Moreira Marques, Karla Nívea Sampaio, Alciene Almeida Siqueira, Vítor Sampaio Minassa

Publikováno v: Journal of Chromatography B. :44-53

Organophosphorus (OP) compounds stand out as one of the most extensively used pesticides' class worldwide, being associated with a high prevalence of voluntary and accidental poisoning in humans. These compounds promote inhibition of the acetylcholin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46aa2a0e46a87a11e2f70e1dfa11912f
https://doi.org/10.1016/j.jchromb.2018.09.006

New evidence for refinement of anesthetic choice in procedures preceding the forced swimming test and the elevated plus-maze

Autor: Alciene Almeida Siqueira, T. Gaigher, Leticia Santos Herbst, Sâmia R.L. Joca, Vanessa Beijamini, Karla Nívea Sampaio

Publikováno v: Herbst, L S, Gaigher, T, Siqueira, A A, Joca, S R L, Sampaio, K N & Beijamini, V 2019, ' New evidence for refinement of anesthetic choice in procedures preceding the forced swimming test and the elevated plus-maze ', Behavioural Brain Research, vol. 368, 111897 . https://doi.org/10.1016/j.bbr.2019.04.011
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Previous studies indicated that some general anesthetics induce long-term antidepressant and/or anxiolytic-like effects. This raises the concern about the use of anesthesia in surgeries that precede psychopharmacological tests, since it may be a pote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147364ce23bce64f439f1a2b0922c66c
https://pubmed.ncbi.nlm.nih.gov/30978407

Atropine counteracts the depressive-like behaviour elicited by acute exposure to commercial chlorpyrifos in rats

Autor: Vítor Sampaio Minassa, Karla Nívea Sampaio, Igor Simões Assunção Felippe, Rita Gomes Wanderley Pires, Alexandre Cunha, Graziany Leite Moreira Marques, Vanessa Beijamini, Alciene Almeida Siqueira, M.A. Cicilini, T. A. Alarcon, Thallis Coelho da Silva Gramelich

Publikováno v: Neurotoxicology and teratology. 71

Acute organophosphate (OP) poisoning induces well-known signs of toxicosis related to acetylcholinesterase (AChE) inhibition. However, the relationship between acute OP poisoning and the onset of psychiatric disorders remains unclear. Thus, we invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ceb3e2569848175d12859891cfa81ad
https://pubmed.ncbi.nlm.nih.gov/30458229