Zobrazeno 1 - 10 of 51 pro vyhledávání: '"Alcides J. M. da Silva"'
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Akademický článek
Second-generation pterocarpanquinones: synthesis and antileishmanial activity
Autor: Viviane dos Santos Faiões, Lívia C. R. M. da Frota, Edézio Ferreira Cunha-Junior, Julio C. F. Barcellos, Thayssa Da Silva, Chaquip Daher Netto, Silvia Amaral Gonçalves Da-Silva, Alcides J. M. da Silva, Paulo R. R. Costa, Eduardo Caio Torres-Santos
Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 1, Pp 1-11 (2018)
Abstract Background Despite the development of new therapies for leishmaniasis, among the 200 countries or territories reporting to the WHO, 87 were identified as endemic for Tegumentary Leishmaniasis and 75 as endemic for Visceral Leishmaniasis. The
Externí odkaz: https://doaj.org/article/c21f424e40fb4359a7e39bbe4c79cc09
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3
Akademický článek
Lapachol and synthetic derivatives: in vitro and in vivo activities against Bothrops snake venoms.
Autor: Marcelo A Strauch, Marcelo Amorim Tomaz, Marcos Monteiro-Machado, Bruno Lemos Cons, Fernando Chagas Patrão-Neto, Jhonatha da Mota Teixeira-Cruz, Matheus da Silva Tavares-Henriques, Pâmella Dourila Nogueira-Souza, Sara L S Gomes, Paulo R R Costa, Edgar Schaeffer, Alcides J M da Silva, Paulo A Melo
Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0211229 (2019)
BACKGROUND:It is known that local tissue injuries incurred by snakebites are quickly instilled causing extensive, irreversible, tissue destruction that may include loss of limb function or even amputation. Such injuries are not completely neutralized
Externí odkaz: https://doaj.org/article/8d51574523bd4b3e9782f51c7d9ece63
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6
Second-generation pterocarpanquinones: synthesis and antileishmanial activity
Autor: Chaquip D. Netto, Eduardo Caio Torres-Santos, Thayssa Da Silva, Edézio Ferreira Cunha-Júnior, Julio C. F. Barcellos, Alcides J. M. da Silva, Lívia C. R. M. da Frota, Viviane dos Santos Faiões, Silvia Amaral Gonçalves Da-Silva, Paulo R. R. Costa
Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 1, Pp 1-11 (2018)
Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 24, Article number: 35, Published: 17 DEC 2018
Journal of Venomous Animals and Toxins including Tropical Diseases v.24 2018
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
The Journal of Venomous Animals and Toxins Including Tropical Diseases
Background: Despite the development of new therapies for leishmaniasis, among the 200 countries or territories reporting to the WHO, 87 were identified as endemic for Tegumentary Leishmaniasis and 75 as endemic for Visceral Leishmaniasis. The identif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8881bcfc1acd6f84ab813978058ffe6
http://link.springer.com/article/10.1186/s40409-018-0174-7
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7
Lapachol and synthetic derivatives: in vitro and in vivo activities against Bothrops snake venoms
Autor: Edgar Schaeffer, Jhonatha Da Mota Teixeira-Cruz, Alcides J. M. da Silva, Marcos Monteiro-Machado, Bruno L. Cons, Paulo R. R. Costa, Pâmella Dourila Nogueira-Souza, Matheus Da Silva Tavares-Henriques, Marcelo A. Strauch, Marcelo A. Tomaz, Sara L. S. Gomes, Paulo A. Melo, Fernando Chagas Patrão-Neto
Publikováno v: PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0211229 (2019)
Background It is known that local tissue injuries incurred by snakebites are quickly instilled causing extensive, irreversible, tissue destruction that may include loss of limb function or even amputation. Such injuries are not completely neutralized
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f9d9624c1de8619bb08e63785fe4c62
https://pubmed.ncbi.nlm.nih.gov/30689661
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8
Chemoselective Ruthenium-Catalyzed C-O Bond Activation: Orthogonality of Nickel- and Palladium-Catalyzed Reactions for the Synthesis of Polyaryl Fluorenones
Autor: Alcides J. M. da Silva, Cédric Schneider, Lívia C. R. M. da Frota, Mauro Barbosa de Amorim, Victor Snieckus
Publikováno v: SYNLETT
SYNLETT, Georg Thieme Verlag, 2017, 28 (19), pp.2587-2593. ⟨10.1055/s-0036-1590985⟩
International audience; Ruthenium-catalyzed C–O bond activation/arylation of methoxy and O-carbamoyl-substituted fluorenones is reported. Established are new reactions of compound 1 (X = H) to aryl (2) and 1,8-diaryl (3) fluorenones. Orthogonal rut
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f4ea608f1357be78dac9916d151c7d
https://hal-normandie-univ.archives-ouvertes.fr/hal-02046273
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10
LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis
Autor: Elmo E. Almeida-Amaral, Grazielle Alves Ribeiro, Silvia Amaral Gonçalves Da-Silva, Rossana C. N. Melo, Paulo R. R. Costa, Alcides J. M. da Silva, Marilene M. Canto-Cavalheiro, Edézio Ferreira Cunha-Júnior, Chaquip D. Netto, Roberta Olmo Pinheiro, Eduardo Caio Torres-Santos
Publikováno v: Journal of Antimicrobial Chemotherapy. 68:789-799
Objectives: The pterocarpanquinone LQB-118, previously demonstrated to be effective in vivo via oral delivery, was investigated for its mechanism in selective parasite killing. Methods: Oxidative stress in Leishmania amazonensis was analysed by evalu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a949280191780f457b23d673b5dc0577
https://doi.org/10.1093/jac/dks498
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