Gold nanorod-assisted theranostic solution for nonvisible residual disease in bladder cancer.

Autor: Armanetti P; National Council of Research-Institute of Clinical Physiology, Pisa 56124, Italy., Locatelli I; Division of Experimental Oncology, Urological Research Institute (URI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy.; Department of Urology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy., Venegoni C; Division of Experimental Oncology, Urological Research Institute (URI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy.; Department of Urology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy., Alchera E; Division of Experimental Oncology, Urological Research Institute (URI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy.; Department of Urology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy., Campanella B; National Research Council (CNR), Institute of Chemistry of Organometallic Compounds, Pisa 56124, Italy., Pederzoli F; Division of Experimental Oncology, Urological Research Institute (URI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy.; Department of Urology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.; Università Vita-Salute San Raffaele, Milan 20132, Italy., Maturi M; Department of Industrial Chemistry, Toso Montanari, University of Bologna, Bologna 40129, Italy., Locatelli E; Department of Industrial Chemistry, Toso Montanari, University of Bologna, Bologna 40129, Italy., Tortorella S; Department of Industrial Chemistry, Toso Montanari, University of Bologna, Bologna 40129, Italy., Curnis F; Division of Experimental Oncology, Tumor Biology and Vascular Targeting Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy., Corti A; Division of Experimental Oncology, Tumor Biology and Vascular Targeting Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy., Lucianò R; Department of Pathology, Pathology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy., Onor M; National Research Council (CNR), Institute of Chemistry of Organometallic Compounds, Pisa 56124, Italy., Salonia A; Division of Experimental Oncology, Urological Research Institute (URI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy.; Department of Urology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.; Università Vita-Salute San Raffaele, Milan 20132, Italy., Montorsi F; Division of Experimental Oncology, Urological Research Institute (URI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy.; Department of Urology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.; Università Vita-Salute San Raffaele, Milan 20132, Italy., Moschini M; Division of Experimental Oncology, Urological Research Institute (URI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy.; Department of Urology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy., Popov V; Ascend Technologies Ltd, Southampton SO15 2BG, Hampshire, United Kingdom., Jose J; FUJIFILM Visualsonics Inc., Amsterdam AB 1114, The Netherlands., Comes Franchini M; Department of Industrial Chemistry, Toso Montanari, University of Bologna, Bologna 40129, Italy., Ooi EH; Medical Engineering and Technology Hub, School of Engineering, Monash University Malaysia, Selangor 47500, Malaysia., Menichetti L; National Council of Research-Institute of Clinical Physiology, Pisa 56124, Italy., Alfano M; Division of Experimental Oncology, Urological Research Institute (URI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy.; Department of Urology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Sep 10; Vol. 121 (37), pp. e2411583121. Date of Electronic Publication: 2024 Sep 05.

Topographic modification of the extracellular matrix precedes the onset of bladder cancer.

Autor: Venegoni C; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy., Pederzoli F; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Locatelli I; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy., Alchera E; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy., Martinez-Vidal L; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Di Coste A; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy., Bandini M; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Necchi A; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Montorsi F; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Salonia A; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Moschini M; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Jose J; FUJIFILM Visualsonics Inc., Amsterdam, the Netherlands., Scarfò F; Pathology Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Lucianò R; Pathology Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Alfano M; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.

Publikováno v: Matrix biology plus [Matrix Biol Plus] 2024 Jun 02; Vol. 23, pp. 100154. Date of Electronic Publication: 2024 Jun 02 (Print Publication: 2024).

Micro-mechanical fingerprints of the rat bladder change in actinic cystitis and tumor presence

Autor: Martinez-Vidal, Laura, Chighizola, M., Berardi, M., Alchera, E., Locatelli, I., Pederzoli, F., Venegoni, C., Lucianò, R., Milani, P., Bielawski, K., Salonia, A., Podestà, A., Alfano, M.

Publikováno v: Communications biology, 6:217, 1-12. Nature Research
Martinez-Vidal, L, Chighizola, M, Berardi, M, Alchera, E, Locatelli, I, Pederzoli, F, Venegoni, C, Lucianò, R, Milani, P, Bielawski, K, Salonia, A, Podestà, A & Alfano, M 2023, ' Micro-mechanical fingerprints of the rat bladder change in actinic cystitis and tumor presence ', Communications biology, vol. 6, 217, pp. 1-12 . https://doi.org/10.1038/s42003-023-04572-0

Tissue mechanics determines tissue homeostasis, disease development and progression. Bladder strongly relies on its mechanical properties to perform its physiological function, but these are poorly unveiled under normal and pathological conditions. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7daee452e3ac37b37b01d96bce9b5c23
https://research.vu.nl/en/publications/0b5d7613-3821-4ce3-b059-1593fd1bf7f6

Progressive alteration of murine bladder elasticity in actinic cystitis detected by Brillouin microscopy.

Autor: Martinez-Vidal L; Division of Experimental Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, 20132, Milan, Italy. lamavy1@gmail.com.; Università Vita-Salute San Raffaele, Via Olgettina, 60, 20132, Milan, Italy. lamavy1@gmail.com., Testi C; Center for Life Nano- and Neuro-Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Roma, Italy. claudia.testi@iit.it., Pontecorvo E; Center for Life Nano- and Neuro-Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Roma, Italy.; CrestOptics S.p.A., Via Di Torre Rossa, 66, 00165, Roma, Italy., Pederzoli F; Division of Experimental Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, 20132, Milan, Italy.; Università Vita-Salute San Raffaele, Via Olgettina, 60, 20132, Milan, Italy., Alchera E; Division of Experimental Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, 20132, Milan, Italy., Locatelli I; Division of Experimental Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, 20132, Milan, Italy., Venegoni C; Division of Experimental Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, 20132, Milan, Italy., Spinelli A; Experimental Imaging Centre, San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy., Lucianò R; Pathology Unit, IRCCS Ospedale San Raffaele, 20132, Milan, Italy., Salonia A; Division of Experimental Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, 20132, Milan, Italy.; Università Vita-Salute San Raffaele, Via Olgettina, 60, 20132, Milan, Italy., Podestà A; Dipartimento Di Fisica 'Aldo Pontremoli' and CIMAINA, Università Degli Studi Di Milano, 20133, Milan, Italy., Ruocco G; Center for Life Nano- and Neuro-Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Roma, Italy.; Dipartimento Di Fisica, Universitá Di Roma 'La Sapienza', Piazzale Aldo Moro, 5, 00185, Roma, Italy., Alfano M; Division of Experimental Oncology/Unit of Urology, IRCCS Ospedale San Raffaele, 20132, Milan, Italy.

Publikováno v: Scientific reports [Sci Rep] 2024 Jan 04; Vol. 14 (1), pp. 484. Date of Electronic Publication: 2024 Jan 04.

Boosting intracellular sodium selectively kills hepatocarcinoma cells and induces hepatocellular carcinoma tumor shrinkage in mice.

Autor: Clemente N; Department of Health Science Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy., Baroni S; Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza, 52, 10126, Torino, Italy., Fiorilla S; Department of Health Science Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy., Tasso F; Department of Health Science Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy., Reano S; Department of Department of Translational Medicine, Unit of Muscle Biology, Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy., Borsotti C; Department of Health Science Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy., Ruggiero MR; Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza, 52, 10126, Torino, Italy., Alchera E; Division of Experimental Oncology/Unit of Urology, URI, IRCCS, Ospedale San Raffaele, Milan, Italy., Corrazzari M; Department of Health Science and Interdisciplinary Research Center of Autoimmune Disease (IRCAD), Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy., Walker G; Department of Health Science Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy., Follenzi A; Department of Health Science Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy., Crich SG; Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza, 52, 10126, Torino, Italy. simonetta.geninatti@unito.it., Carini R; Department of Health Science Università del Piemonte Orientale, Via Solaroli, 17, 28100, Novara, Italy. rita.carini@med.uniupo.it.

Publikováno v: Communications biology [Commun Biol] 2023 May 29; Vol. 6 (1), pp. 574. Date of Electronic Publication: 2023 May 29.